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protein folding PhD Projects, Programs & Scholarships

We have 25 protein folding PhD Projects, Programs & Scholarships

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  Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
  Dr H Lu, Dr A Day
Applications accepted all year round

Funding Type

PhD Type

Oxidative protein folding is an important process for the function of many proteins, which includes both folding and formation of native disulphide bonds.
  Mitochondrial protein folding and diseases
  Prof L-Y Lian, Dr D Criddle
Applications accepted all year round

Funding Type

PhD Type

Many diseases, including cancer and neurological disease, stem from mitochondrial dysfunctions often triggered by sudden elevation of agents such as calcium and reactive oxygen species.
  Simulation of the HP-model of protein folding
  Research Group: Dynamical Systems and Statistical Physics
  Dr T Prellberg
Applications accepted all year round

Funding Type

PhD Type

The School of Mathematical Sciences of Queen Mary University of London invite applications for a PhD project commencing in September 2020 for self-funded students.
  Conformational dynamics and protein folding/misfolding of alpha1-antitrypsin studied by state-of-the-art tandem ion mobility mass spectrometry
  Prof K Thalassinos, Prof D Lomas
Application Deadline: 26 June 2020

Funding Type

PhD Type

The protein A1AT is the most abundant circulating protease inhibitor. It is synthesised in the hepatocyte ER and its key target is the enzyme neutrophil elastase.
  Discerning the mechanisms of cell membrane budding by coronavirus non structured proteins nsp3, nsp4 and nsp6
  Dr D Köster, Dr A Dixon
Application Deadline: 7 June 2020

Funding Type

PhD Type

Coronaviruses are positive strand- non-segmented RNA viruses, infect a wide range of hosts including mammalian species and have recently caused the severe acute respiratory syndrome (SARS), the Middle-East respiratory syndrome (MERS) and the current SARS CoV-2 (Covid-19) pandemic.
  A bioinformatics approach to understanding protein solubility tags
  Dr J Warwicker, Dr R Curtis
Applications accepted all year round

Funding Type

PhD Type

The crowded environment of a cell cytoplasm reveals that proteins and other biological molecules co-exist at high macromolecular concentrations.
  Targeting the Arms Factory: The emerging role of the endoplasmic reticulum in plant immunity
  Prof L Frigerio, Dr E Breeze, Prof M Grant
Application Deadline: 7 June 2020

Funding Type

PhD Type

As the protein factory of the cell, the endoplasmic reticulum (ER) underpins the production, folding and quality control of proteins, as well as lipid biosynthesis.
  Mapping the circadian clock-dependent regulation of the secretory pathway
  Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round

Funding Type

PhD Type

The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
  Do Novel Post-Translationally modified peptides Exacerbate COPD?
  Dr EP Reeves, Dr G McElvaney
Applications accepted all year round

Funding Type

PhD Type

Chronic obstructive pulmonary disease (COPD), which includes emphysema and chronic bronchitis, is a leading cause of disability and mortality.
  Structure and function of protein complexes of the eukaryotic glycoprotein folding quality control (ERQC) checkpoint enzyme, UGGT
  Dr P Roversi, Dr C Savva
Application Deadline: 7 June 2020

Funding Type

PhD Type

A wonderfully efficient quality control enzyme in the eukaryotic cell detects and stops glycoproteins that are on the way to be secreted but need time to form properly.
  Modular design of custom protein structures
  Dr F Parmeggiani
Applications accepted all year round

Funding Type

PhD Type

Proteins perform most of the functions in biological systems, from structural support, to movement, communication and catalysis. Our goal is to use modular building blocks to quickly and precisely design novel protein nanomaterials and nanoparticles to control cell behaviour.
  Dynamic cell fate decisions: linking mechanical signals and protein expression dynamics in the developing eye to understand human developmental disorders
  Dr Cerys Manning, Prof N Papalopulu
Applications accepted all year round

Funding Type

PhD Type

Inherited developmental disorders account for much of childhood visual impairment. Development of the eye requires cell fate decisions that balance stem cell proliferation and differentiation.
  The bacterial protein translocation machinery: a target for new strategies against antimicrobial resistance
  Prof I Collinson
Applications accepted all year round

Funding Type

PhD Type

Bacterial resistance to antibiotics is a major problem affecting millions of people across the world. This severely affects treatment of bacterial infections as strains are emerging that are totally resistant to all clinically used antibiotics.
  Understanding the Maturation and Localisation Pathways within the Bacterial Cell Envelope
  Dr P Stansfeld, Prof D Roper
Application Deadline: 7 June 2020

Funding Type

PhD Type

One of the fundamental challenges in biological sciences is to visualise the dynamics of biomolecular machines in high-resolution detail.
  (Photo)Synthetic Biology - Engineering Biohybrid Photosystems For Enhanced Solar Energy Conversion in Devices
  Dr M R Jones
Applications accepted all year round

Funding Type

PhD Type

There is growing interest in the use of photosynthetic proteins in devices for solar energy conversion, biosensing, photosensing, photocatalysis, touch sensing, molecular electronics and biodegradable solar cells.
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