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protein purification PhD Projects, Programs & Scholarships

We have 50 protein purification PhD Projects, Programs & Scholarships

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  Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
  Dr H Lu, Dr A Day
Applications accepted all year round

Funding Type

PhD Type

Oxidative protein folding is an important process for the function of many proteins, which includes both folding and formation of native disulphide bonds.
  Discerning the mechanisms of cell membrane budding by coronavirus non structured proteins nsp3, nsp4 and nsp6
  Dr D Köster, Dr A Dixon
Application Deadline: 7 June 2020

Funding Type

PhD Type

Coronaviruses are positive strand- non-segmented RNA viruses, infect a wide range of hosts including mammalian species and have recently caused the severe acute respiratory syndrome (SARS), the Middle-East respiratory syndrome (MERS) and the current SARS CoV-2 (Covid-19) pandemic.
  Curly, a novel IQGAP protein domain that bends actin filaments: characterisation and novel applications
  Dr D Köster, Prof M Balasubramanian
Application Deadline: 7 June 2020

Funding Type

PhD Type

Actin filaments are central to a large number of biological processes in all domains of life. Dirven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries.
  Unravelling the dynamics of lipid bilayers and membrane proteins and their reaction to toxins and viral infection on the single molecule level using label-free microscopy.
  Prof W W Langbein, Prof P Borri, Dr MY Young, Dr O Castell
Application Deadline: 5 June 2020

Funding Type

PhD Type

Approximately 30% of the proteins in a cell are membrane proteins, which represent more than 60% of all known drug targets and play a critical role in both infection and immunity.
  Determining brain glycosylation in ageing and Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr C Sutton
Applications accepted all year round

Funding Type

PhD Type

Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism.
  Identification and characterisation of bacteriocins from environmental samples active against strains of Clostridium difficile
  Dr C Penfold, Dr K Winzer, Dr Ruth Griffin
Applications accepted all year round

Funding Type

PhD Type

Clostridium difficile is a cause of neonatal enteritis in livestock such as pigs, cattle and horses. Affected animals develop respiratory problems, abdominal distention and bloody diarrhoea leading to weight loss and in extreme cases mortality.
  Myocardial biology with a specific focus on the mechanisms underlying cardiac fibrosis and atrial fibrillation
  Dr S Reilly, Prof C Redwood, Assoc Prof M Lei
Application Deadline: 24 July 2020

Funding Type

PhD Type

Cardiac fibrosis is a hallmark histological feature of structural changes in the myocardium associated with virtually all cardiac diseases (e.g., heart failure, hypertension, atrial fibrillation and myocarditis).
  Functional analysis of novel genes important in the physiology and pathogenesis of the human pathogen Campylobacter jejuni
  Prof D J Kelly
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni and E. coli are the commonest cause of human bacterial gastroenteritis worldwide. Although pathogenic in humans, C.
  PhD in Chemical Biology -- Neuropeptide Research -- University of Vienna
  Prof M Muttenthaler
Applications accepted all year round

Funding Type

PhD Type

Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Bactofilins and the bacterial cytoskeleton
  Dr E Hoiczyk
Applications accepted all year round

Funding Type

PhD Type

Newly developed light and electron microscopy methods are revolutionising our understanding of bacterial cells. Once thought to be simple, bacteria have now been recognised at highly organised cells using many elements previously only known from eukaryotes.
  Bacterial ABC transporters involved in antibiotic resistance and sensing
  Dr A Crow, Prof D Roper, Dr S Gebhard
Application Deadline: 7 June 2020

Funding Type

PhD Type

Type VII ABC transporters are a superfamily of ATP-powered membrane proteins that function in bacterial antibiotic resistance, toxin secretion, cell division and membrane biogenesis [1,2,3].
  Identifying glucose-dependent mechanisms underlying risk factors for Alzheimer’s disease
  Research Group: Pharmacology and Experimental Therapeutics
  Dr R Williamson, Dr S McLean
Applications accepted all year round

Funding Type

PhD Type

Several risk factors for Alzheimer’s disease including diabetes and midlife obesity are age-dependent and have an obvious metabolic component resulting in impaired glucose metabolism.
  Developing novel drugs targeting gut microbiota-accelerated heart diseases
  Dr Y Chen, Prof T Bugg, Dr A Cameron
Application Deadline: 7 June 2020

Funding Type

PhD Type

It is increasing evident that human is a “super-organism”. We co-exist with trillions of microorganisms in our body (collectively named as microbiota), and our health can largely depend on the interrelationship between ourselves and associated microbiome.
  Is epigenetic information is exchanged between sister chromatids to restore chromatin structure and maintain epigenetic information after DNA replication?
  Dr N Francis
Applications accepted all year round

Funding Type

PhD Type

DNA in eukaryotic cells is organized into chromatin. Far from being an inert packing material, chromatin is a rich source of information for gene regulation.
  The role of phase separation in epigenetic inheritance by Polycomb Group proteins.
  Dr N Francis
Applications accepted all year round

Funding Type

PhD Type

In recent years, the role of phase separation in organizing macromolecules in cells is increasingly appreciated. This includes the organization of chromatin into physical and functional domains.
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