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We have 164 protein structure PhD Projects, Programmes & Scholarships
protein structure PhD Projects, Programmes & Scholarships
We have 164 protein structure PhD Projects, Programmes & Scholarships
BARIToNE: Identification of key gene for better barley using AI protein structure modelling (Project code 25E)
Supervisors. Lead supervisor - Dr Runxuan Zhang, James Hutton Institute. Second supervisor - Dr Piers Hemsley, University of Dundee. Read more
Exploiting Deep Learning-based protein structure prediction for function annotation and structural biology
Applications will be reviewed until a suitable candidate is appointed. Protein structural information is crucial for an understanding of protein function and evolution. Read more
Automated Protein Structure Annotation with Advanced Language Models.
This project does not require any previous knowledge of Biology. Proteins are the building blocks of all living organisms’ cells. Read more
Combining ultrafast spectroscopy with nanotechnology to develop new protein analysis tools
Background. Gaining rapid access to information on protein structure in the solution phase is essential to applications ranging from pharmaceutical design and manufacture to the early diagnosis of diseases such as cancer and Alzheimer’s disease using patient blood samples. Read more
Precision Medicine DTP - Improving the prediction and treatment of human genetic disease by exploring the proteome-level impacts of dominant-negative mutations
Research Group:
Institute of Quantitative Biology, Biochemistry and Biotechnology
Background. Most known disease-causing mutations occur in coding regions and affect the ways in which proteins are made. Read more
Protein specific mineralisation and exceptional fossils
Exceptionally preserved fossil assemblages that preserve not only the biomineralised tissues of organisms but also their soft parts, including internal organs, are critical for interpreting the history of life on our planet. Read more
Thylakoid membrane generation in cyanobacteria
Primary Supervisor: Prof Conrad Mullineaux. Co-Supervisor(s): Dr Vidya Darbari. Funding: China Scholarship Council (CSC). Read more
Beyond normal - Proteins in Alien Environments (Ref: AACME-24-050)
What would happen if the liquid enabling life were not water, but a class of molecules with a similar melting range known as 'ionic liquids'? Ionic liquids are, simply, liquids made of ions usually defined as having melting temperatures below 100C, for which there are millions of possible options. Read more
(Bicentenary) Elucidating mechanisms of transient interactions within complex molecular machinery using integrated structural and AI data analyses
Understanding the complex transient interactions between components of molecular machines is critical for our understanding of biological processes and underpins the rationale for this project which seeks to use state-of-the-art laboratory techniques combined with AI methods to unravel complex interactions driving a specific biological process. Read more
Application of Deep Learning (AI) to the refinement of XH-π interactions in protein atomic structure determination
Background. XH-π interactions are an unconventional hydrogen bond involving a polarised HX atom fragment (X being C, N, O or S) and a π-cloud as provided by aromatic residues in proteins. Read more
Determining how phosphorylation drives functional protein interactions
Phosphorylation is one of the most highly studied posttranslational modifications, due to its fundamental importance in regulating protein function, interactions, subcellular localisation, and turnover. Read more
Discovering and characterising new protein antimicrobials
Antibiotic resistant infections are spreading globally and becoming a leading cause of death worldwide, already surpassing malaria and HIV. Read more
Cleave to Modify: A new biological mechanism for protein regulation
Variations in protein structure at the level of amino acid sequence and modifications allow for the biological complexity observed in living organisms; a complexity that far exceeds that of the approximately 20,000 genes in the human genome that encode for proteins. Read more
EASTBIO: Role of protein S-nitrosylation in endothelial cells in hypoxia
Background. Neovascularisation is essential for heart repair and regeneration following myocardial infarction (MI). Nonetheless, present therapies are insufficient to restore cardiac function. Read more
Illuminating Membrane Protein Interactions with Advanced Mass Spectrometry
Description. Membrane proteins perform critical roles in cellular communication and transport, yet studying their interactions remains challenging due to their inherent instability outside lipid-rich environments. Read more