Imperial College London Featured PhD Programmes
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protein crystallography PhD Projects, Programs & Scholarships

We have 44 protein crystallography PhD Projects, Programs & Scholarships

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  Structural and biochemical analysis of inositol pyrophosphate signaling pathways
  Prof M Hothorn
Applications accepted all year round
Applications are invited for a PhD position, starting any time in 2019, in the group Prof. Michael Hothorn at University of Geneva (http://structplantbio.org).
  MRC DiMeN DTP: Dissecting INPP5K function: cell biology, structural determination by X-ray crystallography and enzymology of a key protein implicated in muscular dystrophy, insulin signalling, spastic paraplegias and Parkinsonism
  Dr L Swan, Dr S Antonyuk, Dr M Stagi
Application Deadline: 21 January 2019
The Swan laboratory (https://www.researchgate.net/profile/Laura_Swan), specialists in phosphoinositide lipid biology and the cell biology of membrane trafficking, in collaboration with international teams of clinicians and scientists, have recently discovered that mutations in a specific phosphatase cause a congenital muscular dystrophy with short stature, brain and eye manifestations (papers.
  Molecular basis of pathogenesis: Structure based design of novel therapeutics for the treatment of infectious diseases
  Prof R L Brady
Applications accepted all year round
Through the study of protein structure, primarily using protein crystallography but also electron microscopy and small-angle X-ray scattering, we aim to probe crucial biomolecular interactions central to a variety of diseases.
  Mechanism of transmembrane receptor activation
  Dr M Hyvonen
Applications accepted all year round
Applications are invited for a PhD position, starting in October 2019, in the group Dr Marko Hyvonen at University of Cambridge (http://hyvonen.bioc.cam.ac.uk/) to study the mechanism of transmembrane signalling by TGFbeta family growth factors.
  (BBSRC DTP) Characterization of P450 peroxygenases and their applications in alkene/biofuel production
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2019
The project involves characterization of P450 peroxygenase enzymes, a class of the P450 enzymes which naturally use hydrogen peroxide rather than redox partner systems to drive catalysis.
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 26 July 2019
It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Conformational dependence of glycan geometry in protein glycosylation: applications for macromolecular refinement in atomic structure determination by X-ray crystallography and electron cryo-microscopy
  Dr J Agirre, Dr K D Cowtan
Applications accepted all year round
Proteins are composed of 20 individual building blocks, the L-amino acids, linked together by a largely inflexible amide bond.
  (BBSRC DTP CASE) Driving enzymatic carboxylation using supercritical CO2
  Prof D Leys, Dr S Hay, Prof I Larrosa
Application Deadline: 31 January 2019
The use of CO2 as a chemical feedstock is attractive for various reasons, not least as a means to address the desirable reduction of global CO2 levels.
  Mitochondrial protein quality control and ageing - Interaction of prohibitins with m-AAA proteases at the inner mitochondrial membrane
  Dr A Winter
Application Deadline: 31 January 2019
Mitochondrial protein quality control and ageing - Interaction of prohibitins with m-AAA proteases at the inner mitochondrial membrane.
  Structural biology of membrane-bound glycosyltransferases
  Dr T Allison
Applications accepted all year round
A PhD scholarship (fees and stipend) is available in the Allison Lab at the University of Canterbury in Christchurch, New Zealand.
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