Optimisation of gene expression routes for heterologous protein expression in CHO cells
Dr P Mitchell
Applications accepted all year round
CHO cells are commonly used as a vehicle for the production of heterologous proteins in the biopharmaceutical industry. We are currently using gene knock down and knock in approaches to increase the expression level of target recombinant proteins for potential use in industrial scale applications.
Investigating the effect of telomere length on endothelial cell function
Dr V Codd, Prof NJ Samani
27 January 2019
Telomeres are protein bound DNA repeat structures at the ends of eukaryotic chromosomes, Telomere length (TL) has been proposed as a marker of biological ageing and shorter TL associates with several age related diseases, including coronary artery disease (CAD).