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proteins PhD Projects, Programs & Scholarships

We have 558 proteins PhD Projects, Programs & Scholarships

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  Structure, regulation and dynamics of small G proteins and their interactions with membranes and effector proteins
  Dr H Mott
Applications accepted all year round
Our lab are interested in cell signalling via small G proteins of the Ras superfamily. We use a range of biochemical, biophysical and structural approaches to understand these fascinating proteins, which are involved in multiple cellular processes and are often deregulated in diseases such as cancer.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Application Deadline: 6 January 2019
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  Structure and function of key ABC Transporters in health and disease
  Prof L Carpenter, Dr H de Wet
Application Deadline: 25 January 2019
Human ABC transporters are a family 52 integral membrane proteins that transport diverse molecules across cell membranes. Mutations in ABC transporters causes a range of diseases, including diabetes (ABCC8 and ABCC9), cystic fibrosis (ABCC7, CFTR) and blindness (ABCA4).
  ChromDesign-ITN: Analysis of PCL family of proteins during differentiation (subproject ESR1); Hosting institution: Centre for Genomic Regulation - CRG, Barcelona, Spain
  Dr Luciano DiCroce, Prof G Cavalli
Application Deadline: 21 December 2018
"ChromDesign” is a European innovative and interdisciplinary Research and Training network, which aims to characterize the impact of the 3D chromatin organization on gene regulation during cellular differentiation and in several human disorders, and to train junior researchers in the biomedical field, either in academia or in the private sector.
  The role of matrix interactions in regulating the SPARC family of matricellular proteins.
  Dr N Hill, Dr A Munasinghe
Applications accepted all year round
The SPARC family of matricellular proteins determine the way in which cells respond to their extracellular environment. SPARC family proteins interact with a range of binding partners, including matrix proteins (1).
  The importance of metal binding for the function of rice proteins that interact with pathogen effectors
  Prof C Dennison
Application Deadline: 11 January 2019
Global demand for food is rising and plant pathogens are one of a number of major threats to crop harvests. Plant pathogens produce effector proteins that remodel host cell processes for the benefit of the pathogen, resulting in disease.
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round
Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  Protein quality control and neurodegenerative disease - to test the hypothesis that BAG6 contributes to the quality control of a range of disease-linked proteins in the cytosol
  Dr L Swanton, Prof S High
Applications accepted all year round
Misfolded proteins represent a continuous threat to cell viability, which if allowed to accumulate can disrupt cellular function and induce cell death [1].
  Regulatory roles for ribosome-associated proteins in protein synthesis
  Prof G D Pavitt, Dr M Pool
Applications accepted all year round
Protein synthesis is a highly-conserved, dynamic and tightly controlled process that is central to the activity of all cells. All phases of translation can be controlled.
  (BBSRC DTP)Understanding structure and function of the mechanosensors talin and vinculin
  Dr C Ballestrem, Prof C Baldock, Dr A Roseman
Application Deadline: 31 January 2019
Any aberration in the cells’ ability to sense their environment leads to severe health deficiencies including cancer, deficiencies in wound-healing and inflammation.
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