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proteins PhD Projects, Programs & Scholarships

We have 280 proteins PhD Projects, Programs & Scholarships

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  Structure, regulation and dynamics of small G proteins and their interactions with membranes and effector proteins
  Dr H Mott
Applications accepted all year round

Funding Type

PhD Type

Our lab are interested in cell signalling via small G proteins of the Ras superfamily. We use a range of biochemical, biophysical and structural approaches to understand these fascinating proteins, which are involved in multiple cellular processes and are often deregulated in diseases such as cancer.
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  Functional analysis of fungal effector proteins in the barley/wheat powdery mildew plant-pathogen interactions.
  Dr L Bindschedler, Prof A Devoto
Applications accepted all year round

Funding Type

PhD Type

Pathogens secrete small proteins called effectors or virulence factors which are important for the successful invasion of the host.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  The role of matrix interactions in regulating the SPARC family of matricellular proteins.
  Dr N Hill, Dr A Munasinghe
Applications accepted all year round

Funding Type

PhD Type

The SPARC family of matricellular proteins determine the way in which cells respond to their extracellular environment. SPARC family proteins interact with a range of binding partners, including matrix proteins (1).
  Regulatory roles for ribosome-associated proteins in protein synthesis
  Prof G D Pavitt, Dr M Pool
Applications accepted all year round

Funding Type

PhD Type

Protein synthesis is a highly-conserved, dynamic and tightly controlled process that is central to the activity of all cells. All phases of translation can be controlled.
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
  Dr H Lu, Dr A Day
Applications accepted all year round

Funding Type

PhD Type

Oxidative protein folding is an important process for the function of many proteins, which includes both folding and formation of native disulphide bonds.
  Mapping the circadian clock-dependent regulation of the secretory pathway
  Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round

Funding Type

PhD Type

The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
  Development of Novel Crystallization Methods for Integral Membrane Proteins
  Dr G Patchornik
Applications accepted all year round

Funding Type

PhD Type

Our research is focused on one of the major barriers in Structural biology. growing high quality three dimensional (3D) crystals of integral membrane proteins for structural analysis.
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