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proteomics PhD Projects, Programs & Scholarships

We have 138 proteomics PhD Projects, Programs & Scholarships

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  Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease
  Prof M Lowe, Prof V Allan
Applications accepted all year round

Funding Type

PhD Type

Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway.
  New methods for ultra-high throughput proteomics for biomarker discovery
  Dr R Unwin, Prof A D Whetton
Applications accepted all year round

Funding Type

PhD Type

The ability to reliably measure protein concentrations in blood samples is critical for the identification of disease biomarkers to allow patients’ stratification and improve patient care.
  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  Breast Cancer Omics and Modelling
  Dr C Francavilla, Prof R Breitling
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Breast cancer is the major cause of death among women and 90% of deaths are caused by incurable metastasis.
  Proteomic and mass spectrometric analysis of disease progression in Acute Myeloid Leukaemia
  Prof A D Whetton, Dr Andrew Pierce
Applications accepted all year round

Funding Type

PhD Type

Acute myeloid leukaemia is a disease where unfortunately outcomes have improved little in the recent past and new approaches are required in treatment of the disease.
  Mapping the circadian clock-dependent regulation of the secretory pathway
  Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round

Funding Type

PhD Type

The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
  Proteomic approach to understand mitochondrial quality control under normal and stress conditions
  Dr H Lu, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Defects in protein quality control lead to the accumulation of misfolded and damaged proteins, which play an important role in many diseases (e.g.
  MSc by Research Programme: Bringing proteins together with small molecules
  Prof A Ciulli
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  MSc by Research Programme: Deciphering the ubiquitin codes that regulate protein degradation
  Dr Y Kulathu
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Chloroplast immunity – a novel and key process attacked by pathogens
  Prof M Grant, Dr A Jones
Application Deadline: 7 June 2020

Funding Type

PhD Type

Crop losses due to biotic stress contribute disproportionately to yield losses, generally accounting for ~25% of the crop. Thus, developing novel approaches to restricting pathogen infections of crops and consequently yields must be a key futurey objective.
  Characterising human metalloproteome to disrupt metal toxicity induced neurodegeneration (Ref: SF20/APP/SOUNDARARAJAN)
  Dr M Soundararajan
Applications accepted all year round

Funding Type

PhD Type

Metal accumulation and biometal dyshomeostasis in the nervous system leads to loss of neuronal function.
  Molecular and cell-biological mechanisms mediating establishment of neuron polarity during development
  Dr R Das, Dr C Francavilla
Applications accepted all year round

Funding Type

PhD Type

Background. Cells undergoing neuronal differentiation in the embryonic spinal cord delaminate from the neuroepithelium, resulting in loss of apical cell polarity.
  Partitioning primary and secondary changes of gene expression caused by gene mutations
  Dr D Talavera, Prof G D Pavitt, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Control of gene expression is a complex cell process, which involves balancing both the synthesis and the degradation of RNA and protein so as to establish optimal levels of each protein.
  Understanding cellulose synthesis in plants
  Prof S Turner, Prof S High
Applications accepted all year round

Funding Type

PhD Type

It is clear that there is now enormous pressure to develop much better replacements for plastics derived from fossil fuels. One possibility is to develop novel plastics based on polymers from plants.
  Understanding regulation of gene expression during development via an integrated computational analysis of ‘omics data
  Prof S Hubbard, Prof S Griffiths-Jones, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Embryonic development requires exquisite control of the expression of large numbers of genes, integrating components from the genome, transcriptome and proteome.
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