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proteomics PhD Projects, Programmes & Scholarships
We have 101 proteomics PhD Projects, Programmes & Scholarships
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Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease
Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway. Read more
New methods for ultra-high throughput proteomics for biomarker discovery
The ability to reliably measure protein concentrations in blood samples is critical for the identification of disease biomarkers to allow patients’ stratification and improve patient care. Read more
Genomic and Proteomics-Based Characterisation of Microalgal Cell Factories
Microalgae have generated increasing interest as microbial cell factories to produce proteins, pigments, therapeutics, and nutraceuticals. Read more
Breast Cancer Omics and Modelling
Background and goals. Breast cancer is the major cause of death among women and 90% of deaths are caused by incurable metastasis. Read more
Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact
Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more
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Identifying NMDA receptor complex interactomes of epilepsy associated genetic variants using BioID( Ref: WD_2022_21_WSCH)
Post Summary. Applications are invited from suitably qualified candidates interested in pursuing a PhD in the area of molecular biology on a recently funded research project within the PMBRC at WIT. Read more
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The role of dynamic changes in proteome in pancreatic cancer initiation
Introduction. Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate under 7%. Better understanding of PDAC formation will help improve this. Read more
Mapping ancient biomolecule degradation through omics methods
The University of Manchester faculty of Biology, Medicine and Health (. https://www.bmh.manchester.ac.uk/. ) is offering a unique self-funded PhD studentship in mapping ancient biomolecule degradation using omics techniques. The KNH Centre of Biomedical Egyptology at the University of Manchester (. Read more
A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g. Read more
Do redox regulated post translational modifications lead to catalase moonlighting?
Reactive oxygen species (ROS) and ROS processing enzymes and proteins have been co-opted during evolution into the regulation of plant growth, development and defence. Read more
Identification and characterisation of novel flavivirus protease cleavages sites in mammalian and insect cells using N-terminomics
Positive sense single stranded RNA viruses translate their large open reading frames as a polyprotein that is cleaved by viral and/or host proteases to release mature viral proteins. Read more
TRANSCRIPTOMIC, PROTEOMIC AND BIOINFORMATICS ANALYSES OF CELL-BASED THERAPIES FOR CARTILAGE INJURIES IN HUMANS
Background. Versus Arthritis studentships are prestigious awards within the field of musculoskeletal research. This studentship gives the opportunity to join our Regenerative Medicine team at the RJAH orthopaedic hospital and Keele University. Read more
Ubiquitin-like modifications underlying Cell Differentiation and Biology in Trypanosomes
Post-translational protein modifications are major regulators of eukaryotic cell functions and include modifications by attachment of polypeptides such as ubiquitin and ubiquitin-like proteins (UBLs). Read more
Diversifying the histone code: defining the role of non-canonical phosphorylation in chromatin structure
This opportunity will remain open until the position has been filled. Post-translational modifications (PTMs) of histones are known to direct chromatin structure and thus gene transcription. Read more
Mechanistic understanding of cancer drug induced cardiotoxicity using patient derived induced pluripotent stem cell (iPSC) derived cardiomyocytes
Background. Cardiovascular disease is the number one non-cancer cause of death in cancer survivors, attributable to side-effects of cancer medications routinely given to patients. Read more