Experimental Evolution of Endosymbiosis
Dr H Hendrickson, Dr E Ostrowski
Applications accepted all year round
Complex eukaryotic life began when one free-living cell gave up independence and partnered with another. A major question in evolution concerns how such partnerships are able to form and stabilise.
Targeting stress activated MAPK pathways in eukaryotic pathogens
Prof J Quinn
11 January 2019
Candida albicans is a major fungal pathogen of humans causing over 400,000 deaths per annum. Systemic Candida infections are difficult to treat as current anti-fungal drugs are limited and cause undesirable side-effects.
An ‘Evolve and Resequencing’ based dissection of developmental competence in African trypanosomes
Institute of Immunology & Infection Research
Prof K Matthews
13 December 2018
African trypanosomes are parasites that cause human sleeping sickness and the livestock disease, ‘nagana’ in sub Saharan Africa. These protozoan parasites use ‘quorum sensing’ in their host bloodstream to control the production of an arrested developmental form needed for transmission to their vector, the tsetse fly.