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receptor PhD Projects, Programmes & Scholarships

We have 97 receptor PhD Projects, Programmes & Scholarships

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We have 97 receptor PhD Projects, Programmes & Scholarships

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Therapeutic targeting of chemokines in inflammation

Protein interactions underlie most biological processes but are challenging to target using small molecule drugs. Many protein interactions are mediated by short-linear-interacting motifs (SLiMs) that range from 3-12 amino acid residues (1, 2). Read more

Molecular Modelling of P2X receptor function

P2X receptors (P2XR) are a family of ligand-gated ion channels. P2XRs are activated upon binding of extracellular ATP and allow the influx of small cations after channel opening. Read more

Involvement of P2X7 receptors in cancer

The P2X receptors are a family of ligand-gated receptor channels activated by ATP and other extracellular nucleotides. A member of this family, the P2X7 purinergic receptor has been shown to play a crucial role in various physiological and pathophysiological processes. Read more
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Identifying NMDA receptor complex interactomes of epilepsy associated genetic variants using BioID( Ref: WD_2022_21_WSCH)

Post Summary. Applications are invited from suitably qualified candidates interested in pursuing a PhD in the area of molecular biology on a recently funded research project within the PMBRC at WIT. Read more

Allosteric targeting of the prostaglandin receptor EP2 to promote neuroprotection against excitoxicity

  Research Group: Wellcome-Wolfson Institute for Experimental Medicine
Excitotoxicity occurs upon brain injury or neurodegenerative diseases and exacerbates associated neuronal damages. The prostaglandin E2 receptor (EP2) has neuroprotective properties against excitotoxicity and novel molecules increasing EP2 activity have been recently discovered. Read more

Allosteric targeting of the prostaglandin receptor EP2 to promote neuroprotection against excitoxicity

Excitotoxicity occurs upon brain injury or neurodegenerative diseases and exacerbates associated neuronal damages. The prostaglandin E2 receptor (EP2) has neuroprotective properties against excitotoxicity and novel molecules increasing EP2 activity have been recently discovered. Read more

Probing Viral Receptor-Glycan Interactions using Polyvalent Multifunctional Glycan-Nanoparticle

  Research Group: School of Chemistry
Multivalent viral receptor-glycan interactions are central to viral infection and immune response regulation. However, the underpinning structural mechanisms are often poorly understood, due to a lack of effective probes for such complex, multimeric and flexible proteins. Read more

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