receptor PhD Projects, Programs & Scholarships

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Alzheimer’s disease (AD) is the commonest form of dementia for which currently there is no means of stopping or even slowing the disease.

Identification of mlm receptor antagonists for treatment of cancer

University of Leeds
School of Chemistry

Dr R Foster

Applications accepted all year round

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

Recent high impact publications have identified antagonism of the mlm receptor as a possible target for treatment of cancer. The native ligand of the receptor has been linked to cell proliferation which has been proven to be as a result of increased nitric oxide (NO) concentration.

Interleukin-36 and Its Receptor

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Dr M Nicklin

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

I am exploring how the pro-inflammatory cytokine interleukin-36 can become activated and the structural features of the receptor and the cytokine that allow activation to be recognised in vivo.

Glutamatergic pharmacology and receptor modifications underlying cognitive function in a rodent model of schizophrenia

University of Bradford
Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Dr K Pors, Dr S McLean, Dr S Kantamneni

Applications accepted all year round

Funding Type

PhD Type

Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.

Cognitive deficits are recognised as being a core symptom of psychiatric disorders including schizophrenia.

Structural insights into ligand binding and channel gating in ATP-gated P2X7 receptor

University of Leeds
Faculty of Biological Sciences

Research Group: School of Biomedical Sciences

Dr L H Jiang, Dr S Muench

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

P2X7 receptor, belonging to the ATP-gated ion channel P2X receptor family, exhibits distinct functional and pharmacological properties that are crucial for its role in innate immunity and inflammatory diseases and cancers (Jiang et al., 2013; Caseley et al., 2014; Roger et al., 2014; Wei et al., 2018).

Identification of the Trypanosoma brucei transferrin receptor-recognition site of transferrin (SteverdingDU19SF)

University of East Anglia
Faculty of Medicine and Health Science

Dr D Steverding

Application Deadline: 31 May 2020

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

The transferrin receptor of the protozoan parasite Trypanosoma brucei (TbTfR) is a heterodimeric protein complex encoded by two expression site associated genes, ESAG6 and ESAG7, which shows no homology to the homodimeric human transferrin receptor (hTfR).

Molecular Modelling of P2X receptor agonism and antagonism

University of Leicester
Molecular and Cell Biology

Dr R Schmid

Application Deadline: 7 June 2020

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

P2X receptors (P2XRs) form a family of ligand-gated ion channels activated upon binding of extracellular ATP (for review see [1]).

Novel G Protein-Coupled Receptor interactions with RAMP accessory proteins

University of Sheffield
Department of Oncology and Metabolism

Dr G Richards, Prof T Skerry

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Cell signalling is critical to multicellular organisms and underlies physiology and diseases. Understanding of the ways cells sense and respond to hormones and growth factors is a constantly-evolving field.

Involvement of P2X7 receptors in cancer

Kingston University
Faculty of Science, Engineering and Computing

Dr E Polycarpou

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

The P2X receptors are a family of ligand-gated receptor channels activated by ATP and other extracellular nucleotides. A member of this family, the P2X7 purinergic receptor has been shown to play a crucial role in various physiological and pathophysiological processes.

Ca2+ signalling in neurodegeneration and Alzheimer’s disease

University of Leeds
Faculty of Biological Sciences

Research Group: School of Biology

Prof I A Hope

Applications accepted all year round

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

Human variants of the ryanodine receptor, the main intracellular calcium ion channel, could be responsible for Alzheimer’s disease.

Understanding how the bitter taste receptor, T2R38, regulates the intestinal epithelium - a study from microbiota to the intestinal epithelium

Anglia Ruskin University ARU
School of Life Sciences

Research Group: Biomedical Research Group

Dr H Chichger

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.

Post-transcriptional regulation of transferrin receptor expression in Trypanosoma brucei

Imperial College London
Department of Life Sciences

Dr C Tiengwe

Applications accepted all year round

Funding Type

PhD Type

Funded PhD Project (Students Worldwide)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

The goal of this project is to understand how. Trypanosoma brucei. controls expression of iron regulatory proteins in response to changes in intracellular iron.

Targeting the Gas6-TAM receptor signalling pathway in cancer

University of Portsmouth
School of Pharmacy and Biomedical Sciences

Dr S Hafizi

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Applications are invited for a self-funded 3 year full-time PhD project, to commence in October 2019 or February 2020. The PhD will be based in the School of Pharmacy and Biomedical Sciences and will be supervised by Dr Sassan Hafizi.

Myocardial biology with a specific focus on the mechanisms underlying cardiac fibrosis and atrial fibrillation

University of Oxford
Radcliffe Department of Medicine

Dr S Reilly, Prof C Redwood, Assoc Prof M Lei

Application Deadline: 24 July 2020

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Cardiac fibrosis is a hallmark histological feature of structural changes in the myocardium associated with virtually all cardiac diseases (e.g., heart failure, hypertension, atrial fibrillation and myocarditis).

Accurate energy evaluation of receptor-ligand interaction

The University of Manchester
Department of Chemistry

Prof P Popelier, Dr S De Visser

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Drug design routinely uses existing computational methods to evaluate the interaction energy between receptor (protein) and ligand (drug) in molecular docking.