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receptor regulation PhD Projects, Programs & Scholarships

We have 28 receptor regulation PhD Projects, Programs & Scholarships

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  Understanding the role of the novel apelin receptor ligand apela in the regulation of neuroendocrine function.
  Dr A O'Carroll
Applications accepted all year round
The apelin receptor APJ (1) was first identified as an orphan GPCR, with closest identity to the angiotensin II receptor, type AT1a.
  Functional Selectivity and the Regulation of Receptor-Activated Signaling Pathways
  Dr G Cottrell, Dr D Widera, Dr S Amadesi, Dr A McNeish
Applications accepted all year round
The molecular mechanisms that regulate receptors and receptor-activated signaling pathways in the cardiovascular and nervous systems are complex.
  MRC Precision Medicine DTP: Genome-wide, gene-specific patterns of glucocorticoid-receptor co-regulators critical for growth and skeletal development
  Research Group: The Roslin Institute
  Prof C Farquharson, Prof T Freeman, Prof S Faisal Ahmed, Prof L Savendahl
Application Deadline: 8 April 2019
Background. Glucocorticoids (GCs) are a class of steroid hormones that bind and activate the intra-cellular GC receptor (GR), and regulate transcription of many genes that govern the effects of GCs.
  Circadian control of energy metabolism and inflammation: Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology
  Prof D Ray
Application Deadline: 26 July 2019
Employing a range of approaches to address the physiological importance of the circadian:nuclear receptor system, ranging from population genetics, experimental medicine studies, CRISPR engineered mice, and cell biology.
  Targeting the P2X7 purinergic receptor in melanoma (STOKESLU19SF)
  Dr L Stokes, Dr C Morris
Application Deadline: 31 May 2019
There is much research into trying to regain control of cell proliferation or cell death (apoptosis) in cancer. Different strategies exist to do this and a multitude of individual receptor targets are being identified in tumour cell lines and primary cells.
  Understanding mechanisms of Notch regulation and misregulation in endocytic pathway
  Research Group: Division of Molecular & Cellular Function
  Dr M Baron, Dr R Clarke
Applications accepted all year round
Notch is a developmental signalling receptor with widespread and important roles in metazoan development and also in adult stem cell regulation.
  Targeting the Role of Myeloid Steroid Metabolism in Chronic Inflammation
  Dr R Hardy, Dr P Foster
Applications accepted all year round
Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.
  Analysis of intracellular sCTLA-4 and its contribution to intrinsic cell regulation
  Dr F J Ward, Dr R Abu Eid
Application Deadline: 29 March 2019
Cancer immunotherapy is among the most important recent developments in cancer treatment. Despite its impressive successes, however, the response in some patients is often limited and short lived.
  TREM2 regulation of microglial dynamics
  Prof J Kittler
Application Deadline: 8 April 2019
This studentship is focused on understanding the cellular basis of microglial function through the study of TREM2, with the aim of opening up new avenues for intervention in disease.
  Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam
  Dr M Soller
Applications accepted all year round
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response.
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