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recombinant PhD Projects, Programs & Scholarships

We have 22 recombinant PhD Projects, Programs & Scholarships

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Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
The University of Manchester Faculty of Biology, Medicine and Health
Oxidative protein folding is an important process for the function of many proteins, which includes both folding and formation of native disulphide bonds. Read more
 Supervisors: Dr H Lu, Dr A Day
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing a virus-like particle (VLP) Polio vaccine
University of Reading School of Biological Sciences
Rationale. Poliovirus is a non-enveloped RNA virus, spread via the faecal-oral route, that causes the infectious disease Poliomyelitis (Polio). Read more
 Supervisor: Dr G Mulley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Rheological and mechanical behaviour of fibre composite with nanobiocomposites matrix for aerospace applications
Kingston University Faculty of Science, Engineering and Computing
The applications of nanocomposite materials derived from natural biopolymer components gaining more attraction because of their renewability, biodegradability, flexibility, and their capability of novel functionalities. Read more
 Supervisor: Dr S Vahid
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
The University of Manchester Faculty of Biology, Medicine and Health
Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy. Read more
 Supervisors: Dr J Bruce, Prof K Williams, Dr A P Gilmore
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Protease-resistant antimicrobial peptides to target bacterial and fungal pathogens
The University of Manchester Faculty of Biology, Medicine and Health
Antimicrobial resistance is quickly becoming a serious global health problem. The emergence of multidrug-resistant microbial strains combined with the drying up of the antibiotic pipeline in the pharmaceutical industry has significantly worsened the situation in recent years. Read more
 Supervisors: Dr J Bella, Dr L Tabernero
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Tackling antibiotic resistance: developing a vaccine against gonorrhoea
The University of Manchester Faculty of Biology, Medicine and Health
Gonorrhoea is caused by the Gram-negative bacterium Neisseria gonorrhoeae and is a serious public health problem in developing and developed countries. Read more
 Supervisors: Prof J P Derrick, Dr F Hayes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
The University of Manchester Faculty of Biology, Medicine and Health
Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity. Read more
 Supervisors: Prof A Sharrocks, Prof M Rattray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
University of Cambridge Department of Biochemistry
The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells. Read more
 Supervisor: Prof E D Laue
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Two pore channel segment 2: a new partner in crime for the AMPK-mTORC1 signalling pathway
University of Edinburgh College of Medicine and Veterinary Medicine
We were the first to demonstrate that two pore segment channels (TPC1-3) represent a family of calcium release channels that are preferentially targeted to endolysosomes. Read more
 Supervisor: Prof A M Evans
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Dissecting the tubulin diversity: understanding how tubulin isotypes regulate microtubule networks
University of Hong Kong School of Biomedical Sciences
α/β-tubulin heterodimers form dynamic polymers, microtubules, that are central to cellular processes, such as cell division, cell migration, and organelle transportation. Read more
 Supervisor: Dr J Ti
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Oncogenic reprogramming of immune cells, a novel mechanism of drug-resistance.
University of Leeds Leeds CRUK Cancer Centre
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more
 Supervisor: Dr P Laslo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural and functional analysis of the meiotic synaptonemal complex
University of Leicester Department of Genetics and Genome Biology
  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Meiotic recombination generates novel allelic combinations and is required for normal fertility in sexually reproducing organisms. Read more
 Supervisors: Dr J Higgins, Prof E Louis
 7 June 2020  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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Structural, kinetic and functional characterisation of ion channel function in the gal-3-fibrosome
University of Leicester Department of Respiratory Sciences
4 Year PhD Studentship available to start September 2020. Fibrosis is a common ageing-associated process that affects all organs. Read more
 Supervisors: Prof B Gooptu, Prof G Vuister
 7 June 2020  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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Obtaining mechanistic insights into interplay of multiple effectors of oncogenic RAS molecules
University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. Importantly, about 20% of all human cancers harbour mutations in RAS genes (COSMIC). Read more
 Supervisors: Dr K Tanaka, Dr A Revyakin
 7 June 2020  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
University of Liverpool Institute of Integrative Biology
Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive. Read more
 Supervisors: Prof D G Fernig, Prof C E Eyers
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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