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recombinant PhD Projects, Programs & Scholarships

We have 46 recombinant PhD Projects, Programs & Scholarships

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  The effect of differential glycosylation on human recombinant protein secretion, function and clearance
University of Manchester School of Chemistry
  Dr A Almond, Prof A J Dickson, Dr J Warwicker
Applications accepted all year round
This project aims to investigate the effect of glycosylation on the secretion, physical properties, and functional biological and physiological properties of human recombinant proteins.
Details
Type/Funding
  (A*STAR) Bacterial glycosyltransferases for bioengineering of biologics
University of Manchester School of Chemistry
  Prof S Flitsch, Prof P Barran
Application Deadline: 31 January 2019
Within industry, biologics are usually produced in large bioreactors which are subject to slight manufacturing changes in production and purification which induce variations in glycosylation.
Details
Type/Funding
  Enhancing MHC Presentation of Antigenic Peptides for Cancer Gene Therapy
University of Sheffield Department of Chemical & Biological Engineering
  Dr A Brown
Application Deadline: 25 February 2019
A fully funded PhD studentship, in collaboration with MedImmune, is available in the Department of Chemical and Biological Engineering at the University of Sheffield, starting in October 2019.
Details
Type/Funding
  A pilot study of oral immunotherapy as a treatment to desensitise horses with insect bite hypersensitivity to Culicoides spp
University of Bristol Bristol Veterinary School
  Dr AD Wilson
Applications accepted all year round
The project. Equine Insect Bite Hypersensitivity (IBH) is a Type I IgE-mediated allergy of horses to salivary proteins of Culicoides spp.
Details
Type/Funding
  Bacteriophages of Gram positive bacteria: gateways to infection control
University of Manchester Faculty of Biology, Medicine and Health
  Dr G Xia, Prof J P Derrick
Applications accepted all year round
The rise in antibiotic resistance has prompted a renewed interest in bacteriophage research. A study of the molecular basis for recognition of the bacterial host has applications in detection, vaccine design and control of bacterial infections.
Details
Type/Funding
  Understanding microbial lignin degradation in soil
University of Warwick School of Life Sciences
  Research Group: CENTA - Central England NERC Training Alliance
  Prof T Bugg, Prof E M H Wellington
Application Deadline: 21 January 2019
Project Highlights. Understand microbiology of lignin degradation in soil. Identify novel lignin-degrading bacteria and enzymes. Application to resource recovery from landfill waste.
Details
Type/Funding
  Mitochondrial protein quality control and ageing - Interaction of prohibitins with m-AAA proteases at the inner mitochondrial membrane
Keele University Faculty of Natural Sciences
  Dr A Winter
Application Deadline: 31 January 2019
Mitochondrial protein quality control and ageing - Interaction of prohibitins with m-AAA proteases at the inner mitochondrial membrane.
Details
Type/Funding
  Investigating the Drosophila DF31 protein to gain insight into the mechanisms and chromatin maintenance in animal cells
St George’s, University of London Molecular and Clinical Sciences Research Institute
  Dr S Cotterill, Dr A Nohturfft
Applications accepted all year round
The Drosophila DF31 protein is an abundant ribonucleoprotein that localises to euchromatic regions and is involved in maintaining chromosome structure.
Details
Type/Funding
  The genetic basis of adaptive evolution
University of Birmingham NERC Doctoral Training Centre Studentships with CENTA
  Dr L Leach, Prof J B Brown, Prof J Colbourne, Dr L Orsini
Application Deadline: 21 January 2019
A unique study system (the micro-crustacean Daphnia) is used to identify the mechanisms of adaptation to environmental change. These include epigenetics enabling phenotypic plasticity that may precede and inform the genetic fixation of adaptive traits.
Details
Type/Funding
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
University of Birmingham School of Biosciences
  Dr M Soller, Dr T Knowles
Applications accepted all year round
Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
Details
Type/Funding
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