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recombinant PhD Projects, Programs & Scholarships

We have 74 recombinant PhD Projects, Programs & Scholarships

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  Precision Medicine DTP - Connecting Molecular Profiles to Phenotype: A Proteomic Resource for Assigning Cell Cycle and Senescent States
  Research Group: Institute of Cell Biology
  Dr T Ly, Dr A Lindqvist
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. A hallmark of cancer is aberrant cell cycle control leading to pathological cell proliferation. Cell cycle progression is controlled by key kinases, such as cyclin-dependent kinases (CDKs) and polo-like kinases (PLKs).
  EastBio Understanding the Structural Basis of Encapsulin Assembly for Efficient Engineering of Encapsulated Enzymes
  Dr D Clarke
Application Deadline: 5 January 2020

Funding Type

PhD Type

Co-Supervisors. Dr Stephen Wallace, School of Biological Sciences, University of Edinburgh. Dr. Louise Horsfall, School of Biological Sciences, University of Edinburgh.
  Dissecting the tubulin diversity: understanding how tubulin isotypes regulate microtubule networks
  Dr J Ti
Applications accepted all year round

Funding Type

PhD Type

α/β-tubulin heterodimers form dynamic polymers, microtubules, that are central to cellular processes, such as cell division, cell migration, and organelle transportation.
  Next-generation protein engineering: integration of ab-initio modelling, high-throughput screening and structural fingerprinting by mass spectrometry.
  Research Group: BBSRC White Rose DTP
  Dr E Paci, Dr D Tomlinson, Prof F. Sobott
Application Deadline: 6 January 2020

Funding Type

PhD Type

Recombinant proteins are playing an ever-increasing role as therapeutics and reagents in biotechnology. Rationally engineering proteins requires understanding of the principles behind protein interactions.
  Understanding drug-resistance in myeloid cancer
  Dr P Laslo
Applications accepted all year round

Funding Type

PhD Type

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
  MRC DiMeN Doctoral Training Partnership: Characterisation of OX40L reverse signalling and its role in the pathogenesis of fibrosis
  Dr N.A. Riobo-Del Galdo, Dr F Del Galdo
Application Deadline: 6 January 2020

Funding Type

PhD Type

Scleroderma (SSc) is a prototypic fibrotic disease, in which an autoimmune mediated injury leads to loss of tissue function through accumulation of extracellular matrix in the skin and internal organs.
  MRC DiMeN Doctoral Training Partnership: Nanoinjection: a novel single molecule technique to study alpha-synuclein amyloid toxicity inside neurons
  Dr E W Hewitt, Dr P Actis, Prof S E Radford
Application Deadline: 6 January 2020

Funding Type

PhD Type

Project Aims. The aim of this project is to use nanoinjection to perform the quantitative delivery of alpha-synuclein fibrils or oligomers into the cytoplasm of neurons and then determine how many of each is required to induce cellular stress and death.
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  Evolutionary insights for engineering improved globin oxygen carriers
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round

Funding Type

PhD Type

Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
  MRC DiMeN Doctoral Training Partnership: Elucidating Disease Mechanisms using New Approaches to Capture Transient Protein Complexes in the Mitochondria
  Prof L-Y Lian, Prof A J Wilson
Application Deadline: 6 January 2020

Funding Type

PhD Type

The mitochondria is the powerhouse of the cell. Its malfunction is the cause of many diseases, ranging from cancer to heart and neurological diseases, which become more prevalent with age.
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