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regulation of gene expression PhD Projects, Programs & Scholarships

We have 64 regulation of gene expression PhD Projects, Programs & Scholarships

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  Understanding regulation of gene expression during development via an integrated computational analysis of ‘omics data
  Prof S Hubbard, Prof S Griffiths-Jones, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Embryonic development requires exquisite control of the expression of large numbers of genes, integrating components from the genome, transcriptome and proteome.
  Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression
  Dr D Blažek, Assoc Prof Z Zdráhal, Dr P Alexiou
Application Deadline: 31 October 2019

Funding Type

PhD Type

CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development.
  Evolution of gene regulatory networks after gene duplication
  Research Group: Lymphocyte Development
  Prof M Merkenschlager, Dr P Sarkies
Application Deadline: 1 December 2019

Funding Type

PhD Type

Throughout evolution multicellular organisms have experienced large-scale structural alterations, in which regions of the genome or even the entire genome have been duplicated (1-7).
  Partitioning primary and secondary changes of gene expression caused by gene mutations
  Dr D Talavera, Prof G D Pavitt, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Control of gene expression is a complex cell process, which involves balancing both the synthesis and the degradation of RNA and protein so as to establish optimal levels of each protein.
  Methionine adenosyltransferases in disease and regulation of gene expression
  Dr S Antonyuk, Prof S Hasnain
Applications accepted all year round

Funding Type

PhD Type

Transmethylation, the transfer of a methyl group from one molecule to another, is a fundamental chemical reaction that plays a central role in important biological processes such as gene expression, cell growth and apoptosis.
  Regulation of gene expression in Drosophila ovarian germline stem cells
  Prof H Ashe, Prof M Ashe
Applications accepted all year round

Funding Type

PhD Type

Drosophila germline stem cells (GSCs) are a premier model for understanding stem cell regulation. Upon division, one GSC daughter remains a stem cell, whereas the other differentiates into a cystoblast (CB).
  Interdisciplinary dissection of rules for gene regulation during neural development
  Dr N Luscombe, Dr J Briscoe
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year joint Crick PhD studentship is offered in the labs of Dr Nicholas Luscombe & and Dr James Briscoe’s Group based at the Francis Crick Institute (the Crick).
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

MMP13 (collagenase 3) plays a vital role in the pathogenesis of osteoarthritis (OA) because MMP13 preferentially cleaves type II collagen, the main component of cartilage, and both MMP13 levels and enzymatic activity are enhanced in OA.
  Molecular Mechanisms for the Regulation of IL-10 Production in T Cells
  Dr A O’Garra.
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Anne O’Garra’s Group based at the Francis Crick Institute (the Crick). Interleukin (IL)-10 is critical for limiting the immune response to pathogens, therefore preventing immunopathology [1].
  How does a mammalian cell physically organise the complex processes of gene expression and regulation?
  Research Group: Biomedical Sciences Research Centre
  Dr J Sleeman
Application Deadline: 1 December 2019

Funding Type

PhD Type

Accurate gene expression and regulation in mammalian cells is a hugely complex process, essential for cellular and organismal homeostasis.
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