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regulatory PhD Projects, Programs & Scholarships

We have 127 regulatory PhD Projects, Programs & Scholarships

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  Gene Regulatory Networks in Development and Disease
  Dr T Sauka-Spengler
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory focuses on deciphering gene regulatory networks that govern complex programmes during early vertebrate development.
  Gene Regulatory Networks in Development and Disease
  Dr T Sauka-Spengler
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory focuses on deciphering gene regulatory networks that govern complex programmes during early vertebrate development.
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
  How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function
  Dr K Couper, Prof R K Grencis
Applications accepted all year round

Funding Type

PhD Type

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state.
  Control of antibiotic production through synthetic biology of bacterial hormone signalling
  Prof E Takano, Prof R Breitling
Applications accepted all year round

Funding Type

PhD Type

There is an urgent need for new antibiotics due to an increase in antibiotic resistance. To produce these essential drugs efficiently in biotechnological systems, we need to have a better understanding of the regulatory mechanisms of antibiotic production.
  Combining Synthetic Biology and Modelling to Understand and Predict Evolution
  Dr M Lagator, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Mutations, and their effects on organismal fitness, lie at the heart of understanding and predicting evolution. Because of its central role in determining evolutionary outcomes, much experimental and theoretical effort has been put into describing the fitness effects of mutations.
  Integrative statistical inference methods for eukaryotic gene regulation with applications to embryonic stem cell differentiation
  Dr I Iqbal, Prof M Rattray, Prof A Sharrocks
Applications accepted all year round

Funding Type

PhD Type

Embryonic stem cells (ESCs) can differentiate into different cell types through intermediary cell states and deeper understanding of the regulatory control underlying these differentiation stages is a very important topic in the study of mammalian development (Yang et al., 2014 & 2019).
  The evolution of the neurogenic gene regulatory networks in Bilateria
  Dr R FEUDA, Dr E Rosato
Application Deadline: 7 June 2020

Funding Type

PhD Type

The evolution of the nervous system is one of the most important innovations in the evolutionary history of animals. Because neurons are present in deuterostome (e.g.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Laboratory of Gene Regulation
  Prof D Higgs, Prof J Hughes, Dr R Gibbons, Dr V Buckle
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation.
  Targeted engineering of quantitative traits in plants
  Dr J Gutierrez-Marcos, Dr G Barker
Application Deadline: 7 June 2020

Funding Type

PhD Type

Our ability to develop novel beneficial crop traits has significantly improved over the last century, although the ability to maintain this trajectory is limited by allelic diversity.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy
  Prof K Gaston, Dr P-S Jayaraman
Applications accepted all year round

Funding Type

PhD Type

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies.
  Post-transcriptional regulation of transferrin receptor expression in Trypanosoma brucei
  Dr C Tiengwe
Applications accepted all year round

Funding Type

PhD Type

The goal of this project is to understand how. Trypanosoma brucei. controls expression of iron regulatory proteins in response to changes in intracellular iron.
  Regulatory roles for ribosome-associated proteins in protein synthesis
  Prof G D Pavitt, Dr M Pool
Applications accepted all year round

Funding Type

PhD Type

Protein synthesis is a highly-conserved, dynamic and tightly controlled process that is central to the activity of all cells. All phases of translation can be controlled.
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