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We have 225 resistance PhD Projects, Programmes & Scholarships

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resistance PhD Projects, Programmes & Scholarships

We have 225 resistance PhD Projects, Programmes & Scholarships

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

  Research Group: Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more

How do interactions in the microbiome shape the evolution of antibiotic resistance in bacterial pathogens?

Antibiotic resistance in pathogenic bacteria poses a fundamental threat to human health. It is estimated that antibiotic resistant infections are already directly responsible for at least one million deaths per annum and this number is predicted to rise dramatically by 2050. Read more

Decoding the epigenetic mechanisms of drug resistance in aggressive breast cancers

Breast cancers pose a major health burden to modern world as being the most common cancer in women. Estrogen receptor (ER), the classical marker of 70% these cancers, is the nuclear receptor important for cancer progression. Read more

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