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retinal PhD Projects, Programs & Scholarships

We have 32 retinal PhD Projects, Programs & Scholarships

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We have 32 retinal PhD Projects, Programs & Scholarships

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Characterisation and treatment of patient iPSC-derived retinal organoids as an in vitro model of inherited retinal disease

Commercial partner: . Newcells Biotech. , Newcastle upon Tyne . Induced pluripotent stem cell (iPSC) derived 3D retinal organoids (ROs) mimic the architecture of the mammalian retina and can therefore be used as a physiologically relevant in vitro model. Read more

Stem Cells: Developing pluripotent stem cell models of inherited retinal diseases

Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide. Read more

CRISPR manipulation of gene expression in retinal organoids to model and rescue human disease

Human pluripotent stem cells can be used in the lab to grow 3D retinal structures called retinal organoids. This allows us to investigate both the early and later events of human eye development and disease. Read more

Improving Automated Retinal Image Analysis Using Deep Learning

Diabetic retinopathy is a major complication affecting people with diabetes and can be detected by retinal scans. NHS Grampian uses a software (DRIA-2) to automatically such images and thus reduce the workload on practitioners. Read more

Developing optogenetic therapies for retinal degeneration

Retinal degeneration is the leading cause of blindness in developed countries. The new exciting biological approach of optogenetic therapy in which ectopic expression of photosensitive proteins (photopigments) is used to restore photosensitivity, offers a potential breakthrough for treating these conditions. Read more

Towards understanding age-related macular degeneration: dysregulation of oxidative stress response and protein homeostasis in the retinal pigment epithelium

Background. Age-related macular degeneration (AMD) is the leading cause of impaired vision, and often blindness in adults. Although a multitude of genetical and environmental factors contribute to its development, ageing represents the highest risk factor. Read more

CRISPR-activation to prevent genetic eye disease

Mutations causing a lack of sufficient protein activity resulting from haploinsufficiency or hypomorphic alleles are the cause of most inherited retinal dystrophies (IRDs). Read more

MRC Enterprise Studentship Programme 2022 (industrial CASE awards)

Eight industrial CASE (iCASE) studentships are available for doctoral study at Oxford, to start in October 2022. Each iCASE studentship is fully-funded for four years with a stipend of the UKRI stipend level + £2,500 p.a., all course fees paid, plus a research training support grant. Read more

MRC Enterprise Studentship Programme 2022 (industrial CASE awards)

Eight industrial CASE (iCASE) studentships are available for doctoral study at Oxford, to start in October 2022. Each iCASE studentship is fully-funded for four years with a stipend of the UKRI stipend level + £2,500 p.a., all course fees paid, plus a research training support grant. Read more

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