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rheumatoid PhD Projects, Programs & Scholarships

We have 11 rheumatoid PhD Projects, Programs & Scholarships

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  Using statistical and functional analysis to investigate the contrasting disease specific roles of IL6R and the chr17q12 locus in the development of rheumatoid arthritis and asthma
  Dr J Curtin, Prof A Simpson
Applications accepted all year round

Funding Type

PhD Type

The Arthritis Research UK and Respiratory Centres at the University of Manchester have extensive research programmes investigating the genetic components of rheumatoid arthritis (RA) and asthma.
  Functional and –omics investigation of neutrophil activation in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots, Dr M Phelan
Applications accepted all year round

Funding Type

PhD Type

Neutrophils are key effector cells in the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus and vasculitis.
  Molecular analysis of neutrophil extracellular traps (NETs) in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots
Applications accepted all year round

Funding Type

PhD Type

Neutrophil extracellular traps (NETs) kill pathogens via the release of chromatin and anti-microbial granule enzymes in an extracellular mesh or “net”.
  Investigating the role of connexins in the gingival response to the oral microbiota
  Dr J Butcher, Dr C Wright, Dr P Martin
Applications accepted all year round

Funding Type

PhD Type

Project reference number. SHLS19005. Periodontal disease (PD) is a chronic inflammatory and bone destructive disease that imposes a substantial social and economic burden, and has been linked to the initiation and progression of cardiovascular disease, diabetes, rheumatoid arthritis, and Alzheimer’s disease.
  Exploring the influence of treatment on CD4+ T-cell sub-populations in patients receiving biologic drugs for their inflammatory arthritis
  Prof A Barton, Dr D Plant, Dr S Viatte
Applications accepted all year round

Funding Type

PhD Type

Background. Tumour necrosis factor inhibitor (TNFi) therapy is ineffective for approximately 20% of rheumatoid arthritis (RA) patients and there is currently no way to predict which patients will not benefit.
  Transferability of genetic risk scores for complex human diseases across diverse population groups
  Dr AM Morris, Dr J Bowes
Applications accepted all year round

Funding Type

PhD Type

Genome-wide association studies (GWAS) have been extremely successful in identifying DNA variants that are associated with a wide range of complex human traits and common diseases.
  A potential role for Epithelial Mesenchymal Trans differentiation (EMT) in the Pathogenesis of Periodontal Disease
  Prof PR Cooper, Dr M Milward
Applications accepted all year round

Funding Type

PhD Type

Periodontitis is a ubiquitous chronic inflammatory disease that destroys the supporting structures of teeth; the most common form is chronic periodontitis which if untreated results in the breakdown of soft tissues and bone, ultimately leading to tooth loss.
  Developing a three-dimensional research model of neutrophil-mediated tissue destruction during inflammation
  Dr J Hirschfeld, Prof I L C Chapple, Dr M Grant
Applications accepted all year round

Funding Type

PhD Type

Background. The proposed research has the goal to develop a novel 3D model to measure and visualise tissue destruction mediated by migrating neutrophils in vitro.
  Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways.
  Prof N J Gay
Applications accepted all year round

Funding Type

PhD Type

This group participates in the Wellcome Trust 4 year PhD programme in Developmental biology., MRC and BBSRC Doctoral Training Programmes.
  Exploring aberrant inflammasome activation in chronic granulomatous disease
  Dr S Webster, Prof C E Bryant
Applications accepted all year round

Funding Type

PhD Type

This project will test the hypothesis. Aberrant inflammasome activation can be caused by mitochondrial ROS mediated NLRP3 inflammasome activation.
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