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rheumatoid PhD Projects, Programmes & Scholarships
We have 12 rheumatoid PhD Projects, Programmes & Scholarships
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Metabolomics approaches to understanding the excess risk of cardiovascular disease in rheumatoid arthritis
Cardiovascular disease (CVD) is a major comorbidity and leading cause of death in patients with rheumatoid arthritis (RA) (1). Traditional CVD risk factors (e.g. Read more
Co-designing a peer-led digital resource to support people living with Rheumatoid Arthritis to improve adherence with medication.
Project Overview. Rheumatoid Arthritis is a chronic autoimmune inflammatory disease. Poor adherence to treatment may result in poor health outcomes; enhancing adherence can therefore improve overall effectiveness of treatment. Read more
Immune phenotyping of refractory rheumatoid arthritis disease
Treatment of rheumatoid arthritis (RA) has been transformed with the introduction of targeted therapies twenty years ago (comprising biologic disease modifying anti-rheumatic drugs, bDMARDS; and the more recent small molecule JAK inhibitors). Read more
Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect. Read more
How extracellular matrix components and chemokines are co-ordinated to control immune cell recruitment
Recruitment of immune cells is a critical component of our ability to fight infection from invasive pathogens. However, this process is also central to inflammatory based diseases such as rheumatoid arthritis as well as in a range of cancer pathologies. Read more
De novo synthekines for treatment of autoimmune diseases
De novo synthekines for treatment of autoimmune diseases. Inflammation is essential for responding to infection and tissue damage. Read more
GW4 BioMed2 MRC DTP PhD project: Targeting adipose-derived adipsin for the treatment of arthritis
This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 20 studentships for entry in October 2023. Read more
Helminth products as macrophage “trainers”: a novel therapeutic tool for the treatment of immune mediated diseases
The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more
Common Peripheral Inflammatory Diseases: An Underestimated Stroke Risk Factor
A potential trigger for cryptogenic strokes in young adults is the long-lived hyper-inflammation associated with chronic peripheral inflammatory diseases including inflammatory bowel disease (IBD) and rheumatoid arthritis (RA). Read more
Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c
The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more
Using genetics to uncover clusters of commonly occurring comorbidities in patients with chronic inflammatory diseases
It is well established that people with chronic inflammatory diseases suffer from an increased risk of developing additional chronic diseases (comorbidity) which leads to a lower quality of life and early mortality. Read more
Circadian regulation of chronic inflammatory disease
The circadian clock is a biological timer which allows organisms to align their physiology with the 24h environment generated by Earth rotating on its axis. … Read more
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