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rheumatoid arthritis PhD Projects, Programs & Scholarships

We have 19 rheumatoid arthritis PhD Projects, Programs & Scholarships

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  Using statistical and functional analysis to investigate the contrasting disease specific roles of IL6R and the chr17q12 locus in the development of rheumatoid arthritis and asthma
  Dr J Curtin, Prof A Simpson
Applications accepted all year round
The Arthritis Research UK and Respiratory Centres at the University of Manchester have extensive research programmes investigating the genetic components of rheumatoid arthritis (RA) and asthma.
  Molecular analysis of neutrophil extracellular traps (NETs) in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots
Applications accepted all year round
Neutrophil extracellular traps (NETs) kill pathogens via the release of chromatin and anti-microbial granule enzymes in an extracellular mesh or “net”.
  The role of CD4+ T-cells specific for GRP78 in the pathogenesis of rheumatoid arthritis (RA)
  Dr S Viatte, Prof A Barton, Mr P Martin
Application Deadline: 31 March 2019
Background. Rheumatoid arthritis (RA) is a complex autoimmune disease of unknown aetiology. Our understanding of mechanisms underlying the cause of the disease is still very limited, which prevents the development of efficient treatment strategies.
  Functional investigation of genetic variants associated with rheumatoid arthritis using CRISPR-Cas9
  Dr G Orozco, Dr S Eyre
Application Deadline: 31 March 2019
The aim of this PhD project is to characterise gene regulatory elements (enhancers) harbouring rheumatoid arthritis (RA) associated variants, in order to determine the genes, biological pathways and mechanisms by which these variants act in specific cell subtypes to increase the risk of disease.
  Identification of genetic and genomic factors underpinning excess risk of rheumatoid arthritis in females
  Dr D Plant, Prof A Barton
Application Deadline: 31 March 2019
Affecting over 400,000 adults in the UK, rheumatoid arthritis (RA) is a common disease that causes pain, swelling and damage in the joints.
  Functional and –omics investigation of neutrophil activation in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots, Dr M Phelan
Applications accepted all year round
Neutrophils are key effector cells in the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus and vasculitis.
  Psoriatric arthritis (PsA)
  Dr G Jones, Dr R Hollick
Application Deadline: 22 March 2019
Psoriatic arthritis (PsA) affects around 120,000 people in the UK. In addition to psoriasis (skin disease) patients can have inflamed, stiff and painful joints which, in severe cases, can become permanently deformed or damaged, and may require surgery.
  Cardiovascular health in patients with inflammatory joint diseases: a genetic approach to understanding excess mortality
  Dr J Bowes, Prof A Barton, Dr S Verstappen
Application Deadline: 31 March 2019
Patients with chronic inflammatory joint diseases, such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA), have increased mortality compared to the general population.
  Investigating the role of connexins in the gingival response to the oral microbiota
  Dr J Butcher, Dr C Wright
Application Deadline: 14 April 2019
Project Description Background. Periodontal disease (PD) is a chronic inflammatory and bone destructive disease that imposes a substantial social and economic burden, and has been linked to the initiation and progression of cardiovascular disease, diabetes, rheumatoid arthritis, and Alzheimer’s disease.
  The role of cells in the persistence of inflammation
  Prof C Buckley
Applications accepted all year round
A characteristic feature of chronic inflammatory reactions is their persistence and predilection for certain sites. Our group investigates the role that tissue resident stromal cells (fibroblasts) play in determining both the switch to persistence as well as the site at which inflammation occurs.
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