Psoriatric arthritis (PsA)
Dr G Jones, Dr R Hollick
22 March 2019
Psoriatic arthritis (PsA) affects around 120,000 people in the UK. In addition to psoriasis (skin disease) patients can have inflamed, stiff and painful joints which, in severe cases, can become permanently deformed or damaged, and may require surgery.
Investigating the role of connexins in the gingival response to the oral microbiota
Dr J Butcher, Dr C Wright
14 April 2019
Project Description Background. Periodontal disease (PD) is a chronic inflammatory and bone destructive disease that imposes a substantial social and economic burden, and has been linked to the initiation and progression of cardiovascular disease, diabetes, rheumatoid arthritis, and Alzheimer’s disease.
The role of cells in the persistence of inflammation
Prof C Buckley
Applications accepted all year round
A characteristic feature of chronic inflammatory reactions is their persistence and predilection for certain sites. Our group investigates the role that tissue resident stromal cells (fibroblasts) play in determining both the switch to persistence as well as the site at which inflammation occurs.