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We have 9 ribosome PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
ribosome PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 9 ribosome PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Identification of the role of small nucleolar RNAs in cartilage ageing
University of Liverpool
Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
To reduce health inequities and improve the lives of older people we need to understand the ageing process at the molecular level. Read more
Regulatory roles for ribosome-associated proteins in protein synthesis
Protein synthesis is a highly-conserved, dynamic and tightly controlled process that is central to the activity of all cells. All phases of translation can be controlled. Read more
Understanding the structural consequences of ribosome specialisation
Protein synthesis by ribosomes (translation) and its regulation is essential to life. While it has been traditionally thought that ribosomes were not involved in the regulation of translation, it is now becoming clear that they do contribute. Read more
SnoRNA dysregulation is a driver of chondrocyte ageing and contributes to osteoarthritis
University of Liverpool
Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Background. Osteoarthritis is a leading cause of disability especially in our ageing society affecting 10% men and 18% women over 60 years old becoming one of the major health problems in the western world. Read more
Protein Quality Control pathways at the endoplasmic reticulum
Around 30% of the proteome, including secretory proteins, plasma membrane proteins, and proteins targeted to organelles require the endoplasmic reticulum (ER) for their biosynthesis. Read more
Specialised ribosomes in cancer: structural, biochemical and functional characterisation
he concept of specialised ribosomes with distinct protein and RNA composition and functional diversity has been recently proposed. Rapid proliferating… Read more
The development of new antiviral agents targeting HIV-1
Even before the current global COVID-19 pandemic, the threat posed to human health by viruses was extensive and although significant progress in targeting some viruses (e.g., HIV-1 and hepatitis C) has been made, challenges remain. Read more
MSc by Research: Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus
Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more
How GABA neurones in the DVC control glucose metabolism
The Dorsal Vagal Complex (DVC) of the brain is an important regulator of glucose metabolism and food intake. The Nucleus of the Solitary Tract (NTS) in the DVC senses insulin and triggers a neuronal relay to decrease hepatic glucose production (HPG) in rodents. Read more
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