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rnai PhD Projects, Programmes & Scholarships
We have 12 rnai PhD Projects, Programmes & Scholarships
MScR - In vivo characterisation of novel risk genes for Alzheimers disease identified by Genome Wide Association Studies
Genome Wide Association Studies (GWAS) for Alzheimer’s disease (AD) have identified a number of genes that are significantly associated with the disease (van der Kant et al., 2019). Read more
MSc by Research: Deciphering the role(s) of Cdk1 during oocyte meiosis
Meiosis is a specialised type of cell division that produces haploid daughter cells known as gametes that are important for sexual reproduction. Read more
MSc by Research: Genetic interactions and novel genes that regulate lignin biosynthesis and straw quality in barley
Lignin is a major component of plant cell walls, and has a significant influence on the digestibility and uses of plant biomass. The lignin biosynthesis pathway has been one of the most intensively studied. Read more
Early life environment changes how organisms age.
This project will help understand why organisms age differently by establishing the effect of early life environments on epigenetic ageing in the model insect, Nasonia vitripennis. Read more
A novel role in mitochondrial homeostasis for the anti-ageing factor RBBP5
The mitochondrion has evolved from the endosymbiotic interaction of an alpha-proteobacterium and an archaeon. One major event during this evolution was the transferring of genes from the symbiont to the host. Read more
The cellular response to stress: roles in disease and ageing
All living organisms need to adapt to their environment in order to survive and reproduce. They must respond to many stresses including altered oxygen levels, heat or cold, irradiation, infection and injury. Read more
Next Generation Oligonucleotide Drugs for Gene Therapy
Synthetic oligonucleotides are short strands of DNA that can be used to treat or manage a wide range of diseases, for example by silencing malfunctioning genes. Read more
Bidirectional mobile sRNA signalling in pea-downy mildew interactions
Plants are constantly being challenged by microbial pathogens and they have evolved the capacity to detect and defend against these incoming microbes. Read more
Musculoskeletal Ageing and Inflammation Research
We are seeking talented, motivated students with a passion for research in musculoskeletal ageing and chronic inflammatory diseases (e.g., osteoarthritis and sarcopenia) to join the Musculoskeletal Ageing and Inflammation team led by Prof Simon Jones https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/jones-simon.aspx. Read more
Ion channel signalling in cancer cells
Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more
Molecular characterisation of scavenger receptor ligand binding.
Scavenger receptors have been identified as being important in Human disease and normal physiological responses. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously. Read more
The regulation of scavenger receptors in cancer
The expression of some scavenger receptors has been identified as being poor for cancer prognosis. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously in the Human body. Read more
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