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rnai PhD Projects, Programs & Scholarships

We have 28 rnai PhD Projects, Programs & Scholarships

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  An in vivo genetic screen of lung function candidate genes using tissue specific RNAi in Drosophila melanogaster
  Dr M Georgiou, Dr I Sayers
Application Deadline: 28 February 2019
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of worldwide mortality and morbidity. Current strategies in management depend on accurate diagnosis, followed by appropriate treatment.
  Mechanisms of epigenetic genome regulation
  Research Group: Institute of Cell Biology
  Dr E Bayne
Application Deadline: 13 December 2018
Regulation of eukaryotic genomes occurs in part at the level of epigenetics, whereby heritable changes in gene expression are signalled independently of the underlying DNA sequence.
  Physiological and molecular characterisation of altered root hydraulic properties in rice due to allelic variation or genetic manipulation of plasma membrane intrinsic proteins (PIPs, a class of aquaporins)
  Prof A Price
Applications accepted all year round
A cluster of three PIPs on chromosome 7 of rice are all candidate genes for a drought avoidance locus. These genes are highly expressed in roots and thought to have a major role in root hydraulic conductance.
  Stress mechanisms as modulators of behavioural plasticity in locust swarming behaviour
  Dr S Ott, Dr T Matheson
Application Deadline: 6 January 2019
All animals can tailor their morphology, physiology and behaviour (their 'phenotype') to changing environmental conditions. This phenotypic plasticity entails a reinterpretation of an animal's genetic information.
  Identifying new drugs to combat the virulence mechanisms underlying multidrug-resistant typhoid.
  Dr D Humphreys
Application Deadline: 23 January 2019
Multidrug-resistant typhoid. --------------------------------------------. The world is facing an epidemic of multidrug-resistant (MDR) typhoid fever.
  Transcription control and immune evasion in African trypanosomes
  Research Group: Division of Cell & Molecular Biology
  Prof G Rudenko
Applications accepted all year round
Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round
Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  MRC DiMeN Doctoral Training Partnership: Elucidating new redox-signalling mechanisms that act to maintain healthy tissues during ageing
  Prof E Veal, Prof M Jackson, Dr N Conlon
Application Deadline: 21 January 2019
Project Summary. This iCASE MRC studentship provides an exciting opportunity to use a diverse range of cutting-edge techniques, and exploit the advantages of different model systems, to identify new molecular mechanisms, that protect against ageing/age-associated diseases.
  Building a nervous system: Analysis of transport and assembly mechanisms in synapse formation
  Dr M Kittelmann, Prof I Bermudez, Prof A McGregor
Application Deadline: 3 January 2019
In order for animals to react to an internal or external stimulus with the appropriate behaviour, the input signals need to be received, processes and transmitted correctly to the effector cells, e.g.
  Host proteins targeted by the CSEP family 21 effectors from the biotrophic pathogenic fungus Blumeria graminis causing powdery mildew in barley
  Dr L Bindschedler, Dr T Bozkurt
Application Deadline: 15 January 2019
Fungi are major actors in spoiling crops and reducing food yield. Among them, powdery mildews are a class of obligate fungal pathogens affecting major agricultural and horticultural crops such as cereals, grape, zucchini or strawberry, thus having a major impact on food production, in the UK and globally.
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