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scaffold PhD Projects, Programmes & Scholarships
We have 14 scaffold PhD Projects, Programmes & Scholarships
Sustainable electroactive 3D-neural scaffold technology to advance neurological disease research
Background. Neurological diseases are currently the 2nd leading cause of death, and the leading cause of disability adjusted life years (DALY) worldwide1. Read more
Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer
Research Group:
Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more
Systematic Exploration of 3D Pharmaceutical Space using 3D Bifunctional Building Blocks
There is much interest in 3D heterocyclic scaffolds for medicinal chemistry. Within fragment-based drug discovery, we are developing a synthetic platform to enable the elaboration of 2D fragments into 3D lead compounds, addressing limitations highlighted by industry. Read more
Tissue engineering of cardiovascular implants
The Project. Our lab is working on tissue engineered heart valves (TEHVs). We think that the best way to create a TEHV is by using natural materials. Read more
Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies
Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more
Chemistry PhD: Heteroborolediides: A New Class of Donor-Acceptor Ligand.
Research Group:
Chemistry
Cyclopentadienyl ligands and their derivatives are ubiquitous to modern organometallic and coordination chemistry, their ease of derivatisation offering… Read more
PhD in Chemistry: New antibiotics to kill 'Superbugs' by stopping them dividing
While antibiotics have revolutionised the landscape of medicine saving millions of lives, their misuse has also resulted in the rise of “Superbugs”, which are bacteria resistant to most of the standard antibiotics. Read more
Optical Tissue Stimulation for In vitro Vascularization
At the Programmable Biomaterials Lab (PBL), our goal is to solve some of the major challenges facing large-scale and high-throughput bioproduction via innovative 3D light-assisted programming of matter. Read more
Investigating the Phase separation underlying the transcriptional regulation and 3D chromatin organisation in acute myeloid leukaemia (AML) pathogenesis.
Stipend. Standard Research Council London Rate + Tuition Fees (Home rate) for 3 years. A consumables budget is also provided. Applications are invited for a 3-year PhD studentship based in the Centre for Haematology, Department of Immunology & Inflammation at Imperial College London. Read more
Synthesis of Microcarriers for Focal Drug Delivery to the Brain
For neurodegenerative diseases, where a specific cell type is lost, it is possible to consider replacing these cells to restore the lost function. Read more
Study on Treatment of onychomycosis with soluble microneedles loaded with Terbinafine nanogels
Onychomycosis is difficult to treat, which is one of the difficulties and hotspots in dermatology. Read more
PhD Position in Fundamental and Applied Chemistry of PN Cages
Background. Our group explores geometrically interesting molecules for fundamental and functional chemistry. One area of focus is the development of scaffolds from which substituents can be reliably extended with well-defined bond angles and lengths. Read more
3D-printed drug-eluting auxetic meshes for preventing biofilm formation and capsular contracture associated with breast implants
This is an exemplar PhD project co-supervised by Dr. Zafer Kazanci (School of Mechanical and Aerospace Engineering) and Prof. Karl Malcolm (School or Pharmacy). Read more
Design and 3D-Printing of Biomaterials for Cardiovascular Applications
There is huge scope to replicate the complex nature of tissue, through the design and additive manufacturing (3D printing, 3DP) of biomaterials. Read more
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