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schizophrenia PhD Projects, Programmes & Scholarships

We have 23 schizophrenia PhD Projects, Programmes & Scholarships

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We have 23 schizophrenia PhD Projects, Programmes & Scholarships

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Dissecting the interplay between the kynurenine pathway and extracellular vesicle signalling in schizophrenia

Increased levels of the kynurenine pathway (KP) metabolites L-kynurenine (KYN) and kynurenic acid (KYNA) have been found in the brains of patients with schizophrenia, and have been linked to cognitive impairment in these individuals. Read more

Biological rhythms and the dopamine system in cognitive dysfunction

  Research Group: Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

Paranoia and trust - examining the role of automatic, implicit processes in mistrust and paranoid thinking

Abstract. Paranoid delusions are the most common symptom of psychosis but less severe forms of paranoid ideation and mistrust are common in everyday life and lie on a continuum with the rarer clinical forms (Elahi, Perez Algorta, Varese, McIntyre, & Bentall, 2017). Read more

3D-Printing of implantable devices for the treatment of chronic conditions

Non-adherence to treatment costs the NHS more than £500M each year. Adherence is especially important when treating patients with chronic conditions that require lifetime pharmacological treatment, such as schizophrenia, Parkinson’s disease, HIV and Alzheimer’s disease. Read more
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(BBSRC DTP) Epigenetic mechanisms linking maternal immune activation-induced transcriptional changes to adult behavioural impairment in a neurodevelopmental rat model

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Physical activity, its maintenance and promotion in people with severe mental illness

  Research Group: Nursing and Health
Background. People with severe mental health problems, like schizophrenia or bipolar disorder, can have higher risk of some health conditions like heart disease and diabetes. Read more

Understanding the human thalamus

While the majority of human neuroscience focusses on the cerebral cortex, the macroscopic organisation of mammalian brains is extremely consistent, suggesting the existence of preserved organisational principles which confer an advantage to overall brain function and behaviour. Read more

MRC Precision Medicine: Does severe mental illness predispose to cardiovascular and metabolic disease via an unfavourable adipose storage profile?

  Research Group: Institute of Cardiovascular and Medical Sciences
Project summary. People suffering from severe mental illnesses (such as depression, schizophrenia and bipolar disorder) have a substantially risk of obesity, diabetes and cardiovascular disease. Read more
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EASTBIO: Cellular resolution molecular organisation of brain circuits for episodic memory

  Research Group: Centre for Discovery Brain Sciences
Deanery of Biomedical Sciences. Episodic memories rely on communication within complex neural circuits. The organisation of these circuits is an essential determinant of how they function. Read more

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