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  Exploiting Nanopore sequencing for genome sequencing
  Dr M Loose
Applications accepted all year round
We are exploiting the latest generation Nanopore sequencing approaches to sequence large genomes. Nanopore sequencing is low cost, easy to use and can generate read lengths limited only by the ability to generate suitable input material.
  Development of a single NGS pipeline using a novel universal virus enrichment panel for the detection and typing of viral pathogens.
  Dr L Scobbie, Dr R Gunson
Application Deadline: 14 April 2019
Background. Current routine virology diagnostics rely upon serological methods and novel molecular methods such as real time PCR.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round
Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  Using massively-paralleled sequencing to find the cause of inherited conditions that affect the front of the eye
  Dr M Ali, Prof C Inglehearn
Applications accepted all year round
Eye diseases are a common cause of human disability and many of them are inherited. These include congenital as well as adult-onset conditions and diseases of ageing, and may involve abnormalities at the back of the eye or the anterior eye structures.
  Using next-generation sequencing and CRISPR-Cas9 gene editing to investigate penetrance and phenotypic variation in inherited eye disease
  Dr C Toomes
Applications accepted all year round
Human inherited retinal diseases (IRDs) result from mutations in over 250 different genes, many of them implicated by the Leeds Vision Research Group (eg Panagiotou et al 2017, AJHG 100:960-968; El-Asrag et al 2015, 96:948-54).
  Supporting Behaviour Change: understanding the links between vision and action in controlling and sequencing multiple movement responses and how this degenerates with age.
  Dr E McSorley
Applications accepted all year round
"Active Vision means that in order to fully understand how we see we
must consider vision in terms of the things we do, the actions we take.
We do not passively process our environment in order to then act upon
it rather we actively interact with our visual environment and interrogate
it by moving our eyes to explore it.
  Determining the link between gut microbiome and blood pressure
  Dr F Marques
Applications accepted all year round
Fully funded PhD scholarships are available for both Australian and international students through the School of Biological Sciences and Monash University.
  Analytic methods for detecting and making sense of somatic genomic rearrangements
  Prof A Papenfuss
Applications accepted all year round
Bioinformatics is the application of mathematics, statistics and computational methods to the analysis of molecular biology data.
  Statistical methods for integrating multi-omics sequence data and unveiling molecular underpinnings of non-small cell lung cancer
  Prof Z Luo, Dr L Leach
Applications accepted all year round
The past decade has witnessed tremendous advancements in sequencing technologies, enabling collection of highly accurate and high resolution data on the structure and function of the genome.
  Clinical Genetics: Building the skull – normal and abnormal development
  Prof A Wilkie, Dr S Twigg
Application Deadline: 26 July 2019
Working closely with the craniofacial teams based in Oxford and other UK units, we specialise in the application of whole exome and genome sequencing to children born with a serious malformation of the skull termed craniosynostosis.
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