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We have 142 sequencing PhD Projects, Programmes & Scholarships

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sequencing PhD Projects, Programmes & Scholarships

We have 142 sequencing PhD Projects, Programmes & Scholarships

Application and development of bioinformatics and network theory methods in cardiovascular disease research and pharmacovigilance

To be able to discover novel drug targets we aim to develop software based on network theoretic approaches that are capable to identify mediators and pathways involved in the pathomechanism of various cardiovascular diseases by the analysis of datasets assessed with high throughput molecular biological techniques (e.g. Read more

On-therapy monitoring of oesophageal cancer and recurrence detection: the Blood-based Liquid Sequencing Study (BLISS)

Oesophageal cancer is undergoing a therapeutic revolution, with first-generation immunotherapy trial results reading out in the next 12 months, and second-generation bispecific agents beginning evaluation alongside new targeted agents for Claudin 18.2, Her2, and FGFR. Read more

Developing a clinical pathway to support nurse led whole genome sequencing for neurological diseases

In this project we will develop pathways to enable specialist nurses to request whole genome sequencing (WGS) for adult neurology patients throughout the NHS; improving the efficiency of the process, freeing consultant neurologist time and improving equity of access. Read more

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

Genetics: Genetic studies of developmental eye disorders to investigate genotype-phenotype correlations

Developmental eye defects that affect the front of the eye give rise to a spectrum of congenital ocular phenotypes that affect the cornea, lens, iris, trabecular meshwork or the globe itself. Read more

Decoding the epigenetic mechanisms of drug resistance in aggressive breast cancers

Breast cancers pose a major health burden to modern world as being the most common cancer in women. Estrogen receptor (ER), the classical marker of 70% these cancers, is the nuclear receptor important for cancer progression. Read more

Optimising dynamic scheduling in smart manufacturing through reinforcement learning PhD

This PhD aims to develop an adaptive self-organising solution for dynamic scheduling in job-shop manufacturing. The research will introduce an innovative approach that integrates deep reinforcement learning and multi-agent systems to rapidly respond to emergencies and disruptions. Read more

Finding the cause of familial facial (Bell’s) palsy

The facial (VII) cranial nerve controls the muscles of facial expression, supplies taste sensation to parts of the tongue and controls a small muscle connected to the ear drum. Bell’s palsy is the clinical condition in which there is impaired function of the facial nerve, associated with facial muscle weakness. Read more

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Fully Funded PhD Scholarship in Soil Molecular Microbial Ecology

Application(s) are invited from suitably qualified candidates for full-time fully funded PhD scholarship starting in September 2024 affiliated to the College of Science and Engineering, School of Biological and Chemical Sciences, Ryan Institute at the University of Galway. Read more
Last chance to apply

EPSRC DTP - 3D bioprinted light responsive hydrogel materials for cartilage tissue analogues

Articular cartilage defects are a significant and health problem for millions worldwide, especially in an aging population. Effective cartilage regeneration remains elusive. Read more

Deciphering the mechanistic drivers of plant-microbe feedback

The soil microbial pool is an untapped reservoir of genetic diversity. In soil, plants form relationships with microbial consortia that aid in nutrient acquisition, plant defence, and general healthy functioning of the plant. Read more

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