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signalling PhD Projects, Programs & Scholarships

We have 201 signalling PhD Projects, Programs & Scholarships

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  Heme regulation of signalling at potassium channels in the cardiovascular system
  Dr N Storey, Dr N W Davies
Application Deadline: 5 May 2019
Ion channels in the smooth muscle of the cardiovascular system control blood pressure and cardiac contractility through changes in their membrane potential.
  Regulation of cancer growth by Rho GTPase and cytoskeletal signalling
  Dr A Elbediwy, Mr P Waller, Dr H Ashrafi
Applications accepted all year round
What is the reason why cells can suddenly switch to uncontrolled cellular growth? What causes the normal formation of cellular contacts and organs to stop growing when reaching their normal size to ignore normal signals and multiply uncontrollably?.
  Define the molecular mechanisms by which PAWS1 controls Wnt signalling
  Dr G Sapkota
Application Deadline: 31 March 2019
University of Dundee, MRC Protein Phosphorylation and Ubiquitylation Unit, Dundee, United Kingdom. Dr. Gopal Sapkota. Wnt signalling plays a fundamental role during development and in adult tissue homeostasis.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round
Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  Molecular dissection of activity-dependent neuronal signalling pathways using quantitative proteomics
  Dr M Collins
Applications accepted all year round
Recent proteomic investigations have identified several thousand proteins in biochemically purified synapses and have uncovered multiprotein complexes essential for synapse function.
  Structure and Function of Innate Immune Signalling in Mosquito Vectors
  Research Group: Dr M Gangloff
  Dr M Gangloff
Applications accepted all year round
Over the course of a long evolutionary history vector-borne pathogens have developed mechanisms to successfully disrupt natural defences in both their mammalian hosts and insect vectors in order to survive and establish infection.
  Proteomic analyses of adhesion signalling in cancer
  Prof M J Humphries, Dr C Jorgensen
Applications accepted all year round
Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation, and they underpin a metazoan (multicellular) existence.
  Systems level analysis of platelet signalling
  Dr M J Fry, Prof J M Gibbins
Applications accepted all year round
We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation.
  Using vaccinia virus to understand Rho GTPase regulation and crosstalk
  Dr M Way
Application Deadline: 18 May 2019
This 4-year PhD studentship is offered in Dr Michael Way’s Group based at the Francis Crick Institute (the Crick). Viruses are obligate intracellular parasites that critically depend on their hosts to generate new progeny.
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