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signalling PhD Projects, Programs & Scholarships

We have 320 signalling PhD Projects, Programs & Scholarships

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  The effects of stress on serotonergic signalling and brain development
  Dr W NORTON, Dr V Straub
Applications accepted all year round
Pre- and early postnatal stress has been shown to affect brain development and adult behaviour, and is a known risk factor for the onset of anxiety and depression in later life.
  Heme regulation of signalling at potassium channels in the cardiovascular system
  Dr N Storey, Dr N W Davies
Application Deadline: 6 January 2019
Ion channels in the smooth muscle of the cardiovascular system control blood pressure and cardiac contractility through changes in their membrane potential.
  Defining the interplay between polycystin 1/2 signalling and cAMP signalling in different subcellular domains
  Prof M Zaccolo
Application Deadline: 25 January 2019
Primary cilia are ubiquitous organelles fundamental for vision, hearing, smell perception, breathing, excretion, reproduction and development and their disruption or loss leads to several diseases (ciliopathies).
  MRC DiMeN Doctoral Training Partnership: Breaking up the fight: Defining the spatial requirements for therapeutic modulation of signalling through FcγRIIa
  Dr j Robinson, Prof A Morgan, Prof A Goldman, Dr M E Webb
Application Deadline: 21 January 2019
Autoantibody-mediated inflammatory diseases are characterised by a proinflammatory feedback loop which leads to the destruction of tissues, prolonged pain, fatigue and subsequent reduction in life quality.
  Non-canonical signalling mechanisms in phagosome maturation
  Prof C E Eyers
Application Deadline: 11 January 2019
Phagosomes are intracellular vesicles that are formed by phagocytosing particles such as bacteria or apoptotic cells by specialised immune cells.
  Analysing the role of FGF signalling in pluripotency and skeletalmuscle development.
  Dr H V Isaacs, Dr M E Pownall
Application Deadline: 7 January 2019
During development, totipotent stem cells give rise to a host of. specialised, differentiated cell types. This process involves the.
  Define the molecular mechanisms by which PAWS1 controls Wnt signalling
  Dr G Sapkota
Application Deadline: 31 December 2018
Wnt signalling plays a fundamental role during development and in adult tissue homeostasis. Aberrant functions of many Wnt components are associated with many human diseases, including cancer and skin disorders.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round
Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  G protein-coupled receptor (GPCR) signalling in the mouse and human gastrointestinal (GI) tract.
  Prof H Cox
Application Deadline: 11 January 2019
To establish the mechanisms of GPR35 signalling in the mouse and human GI tract. GPR35 is an orphan receptor that lacks an endogenous ligand but is highly expressed in mammalian GI tract, particularly in the colon and is implicated in the onset of inflammatory bowel disease (IBD).
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