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signalling PhD Projects, Programmes & Scholarships
We have 204 signalling PhD Projects, Programmes & Scholarships
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Imaging-based analysis of signalling pathways triggered by immune checkpoint receptors
Commercial partner: Gilead Sciences (Oxford). Read more
Cell communication in gastric cancer. MRC GW4 BioMed DTP PhD studentship 2024/25 Entry, PhD in Biosciences
About the GW4 BioMed2 Doctoral Training Partnership. The partnership brings together the Universities of Bath, Bristol, Cardiff (lead) and Exeter to develop the next generation of biomedical researchers. Read more
Biomechanical signalling in human heart disease
About the Project. The human heart undergoes more than 2 billion beats throughout an individual's lifetime, with its rhythm precisely regulated by signalling events that continuously adapt to the biomechanical stress exerted on the ventricular walls. Read more
Biological role of neuropeptides and their receptors
Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more
How do Dysregulated Signalling Pathways cause Intellectual Disability?
The goal of our lab is to understand how signal transduction is disrupted to cause intellectual disability, which is a major healthcare challenge world-wide. Read more
Hypoxia and HIF signalling in TME as regulators of pro- and anti- tumour-associated immune cell functions (ref: SF22/HLS/APP/GIELING)
Hypoxia (low oxygen tension) and hypoxia-inducible factor (HIF)-1 and HIF-2 signalling are environmental cues on the immune system in both acute and chronic human diseases. Read more
Targeting lipid signalling pathways to restore the differentiation capacity of aged satellite stem cells
This project investigates the impact of druggable phosphoinositide signalling pathways on the epigenetic status and transcriptional output of muscle satellite stem cells which controls their differentiation. Read more
Ion channel signalling in cancer cells
Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more
Systems level analysis of platelet signalling
We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation. Read more
Heat shapes plant growth - unravelling crosstalk between temperature and hormone signalling pathways in the control of leaf development
Ambient temperature has profound effects on almost all aspects of plant development, from the onset of seed germination and seedling establishment to flower and fruit production, and thereby also impacts crop quality and yield. Read more
Disrupted SUMO signalling in epithelial cancers, implications for genome stability and response to therapy.
The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2023/24. Read more
Modulation of the Hippo signalling pathway to enhance cardiac regenerative capacity
Common heart diseases such as heart failure (HF) and coronary heart disease (CHD) are characterized by cardiomyocyte loss due to necrosis and apoptosis. Read more
Investigating Platelet and Megakaryocyte Signalling Using Advanced Microscopy Techniques
Investigating Platelet and Megakaryocyte Signalling Using Advanced Microscopy Techniques. Read more
Proteomic analyses of adhesion signalling in cancer
Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation. Read more
MSc by Research: Probing the interplay between IL-33 and GPCR signalling
The immune system plays important roles in both the response to infection and in tissue repair and homeostasis. It is a complex system made up of multiple specialised cell types, each of which must communicate with each other to coordinate an effective response. Read more