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We have 212 signalling PhD Projects, Programmes & Scholarships

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signalling PhD Projects, Programmes & Scholarships

We have 212 signalling PhD Projects, Programmes & Scholarships

Re-purposing established drugs for the resolution of pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Targeting the sweet tooth to curb population-wide sugar intake

Excess intake of dietary sugars are a major contributor to obesity, and type 2 diabetes and 82% of people state that taste is the major determinant of what they buy and eat. Read more

Disease mechanisms in the heart

We are seeking talented, motivated students with a passion for research in inherited cardiac conditions (cardiomyopathies) and biomechanical stress signalling led by Dr Katja Gehmlich (https://www.birmingham.ac.uk/staff/profiles/cardiovascular-sciences/gehmlich-katja.aspx). Read more

The Rhonski project: Examining Rho and Notch signalling in skin development and disease

The skin provides a crucial protective layer between the human body and the outside world. Whilst the epidermis forms a barrier against infection, the inner dermis houses the blood vessels required to sustain the hair follicles and cells contained within both the epidermal and dermal layers. Read more

Uncovering the mechanochemical signalling inputs that drive gastruloid axial patterning

How the early mammalian embryo converts a mass of identical cells in an organism with multiple axes of symmetry (anteroposterior, dorsoventral, mediolateral) is a critical question in developmental biology. Read more

ERK5 MAPK signalling in Alzheimer’s disease

  Research Group: Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more

Exploring the role of tryptophan metabolism in schizophrenia pathogenesis

L-kynurenine (KYN) and kynurenic acid (KYNA) are metabolites of the kynurenine pathway (KP) of tryptophan degradation and have been found to be increased in the brains of patients with schizophrenia. Read more

Manipulation of neuroimmune responses and behaviour by infectious agents

This project is available exclusively to self-funded students who wish to commence study for a PhD in the academic year 2023/24. The project focuses on how infectious agents modify the individuals that they infect and how neuroimmune responses to infection moderate behaviour changes in warm-blooded animals and humans. Read more

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