Medicines Development and Pharmaceutical Sciences
Dr X Liu, Prof D J Tobin
Applications accepted all year round
The transdermal route has many advantages over other routes for the delivery of drugs with systemic activity. These include the ease of use (and withdrawal in the occurrence of side-effects), avoidance of first-pass metabolism, and improved patient compliance.
The epidermis of the skin provides an essential barrier between our bodies and the external environment through the formation of a dense cornified layer of cross-linked proteins and lipids at the surface of the skin.
Skin morphogenesis occurs under stringent control of epithelial-mesenchymal interactions and result in a formation of the epidermis and a number of different skin appendages (including, the hair follicle, HF).
A fully funded PhD studentship in the area of skin care design, with opportunity to work with researchers from 6 leading European universities, 2 global industrial companies and 8 associated industrial partners.
The epidermis of skin is the primary interface between the body and the outside world. As such, the epidermis is constantly under threat of dehydration as there is a permanent driving force for water to leave the skin to the external dry environment.
Our main source of vitamin D is through skin exposure to ultraviolet radiation (UVR) in sunlight. Vitamin D is essential for healthy bones and is associated with reduced incidence of several cancers and immune-mediated disorders.