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stem cell PhD Projects, Programmes & Scholarships
We have 132 stem cell PhD Projects, Programmes & Scholarships
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Integrating mechanical and chemical cues in stem cell migration and division
Adult stem cells are found in most tissues, and the interaction between stem cells and their niche tightly controls their self-renewal and differentiation state. Read more
PhD Student Position – Gene Regulation in Stem Cell Biology and Brain Development
A PhD student position is available for highly motivated individuals with an interest in studying stem cell biology and brain development using a combination of molecular, cellular, genetic, and bioinformatics approaches. Read more
Impact of dietary components on the intestinal stem cell homeostasis and cancer risk
Bowel cancer is the 4th most common and second biggest cause of cancer mortality. Of the ~14,000 new cases of bowel cancer each year in the UK it is estimated 50% could have been prevented through healthy lifestyle changes. For example, there is strong evidence for a high fibre diet preventing bowel cancer. Read more
Mechanistic understanding of cancer drug induced cardiotoxicity using patient derived induced pluripotent stem cell (iPSC) derived cardiomyocytes
Background. Cardiovascular disease is the number one non-cancer cause of death in cancer survivors, attributable to side-effects of cancer medications routinely given to patients. Read more
Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease
Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more
Elucidating the role of disease modifying gene variants in inherited cardiomyopathies using induced pluripotent stem cell derived cardiomyocytes and CRISPR/Cas-9.
Our group is interested in uncovering and understanding key mechanisms of disease that affect cardiac muscle function. We have a particular interest in understanding how regulation of cardiac muscle contraction is altered in common acquired and inherited cardiovascular diseases. Read more
Regulation of asymmetric cell division in brain cancer stem cells
Glioblastoma is the most lethal brain cancer in adults. Its poor prognosis is a result of aggressive tumour growth, therapeutic resistance, and tumour heterogeneity at the cellular and genetic level. Read more
The generation of RBCs in vitro from stem cell sources and the molecular regulation of erythropoiesis in health and disease: towards new therapeutic approaches
Development of systems for the generation of red blood cells (RBCs) from stem cell sources (adult peripheral blood, cord blood and induced pluripotent stem… Read more
Stem Cell Exosomes - Important communicators with therapeutic potential on the dental pulp
The regenerative potential of mesenchymal stem cells has recently been attributed to exosomes, defined as extracellular vesicles of endocytic origin. Read more
4-year PhD Studentship: Apolipoprotein E-targeted stem cell gene therapy for people with Alzheimer’s disease
Alzheimer’s disease (AD) is a devastating progressive neurological disease, and a major increasing global health challenge. Read more
Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more
A10 dopamine neurons: the missing link in cell therapeutics for Parkinson's disease?
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease and degeneration of the nigral dopamine neurons is a key pathological feature of the condition. Read more
Apolipoprotein E-targeted stem cell gene therapy for people with Alzheimer’s disease
Perros Trust-supported 1 Year Full MSc R Scholarship for students of Black or Mixed Black Heritage backgrounds. Project Description. Read more
Control of skeletal muscle regeneration and aging by cell signalling
The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells. Read more
Self funded BMS Project: Therapeutic potential of extracellular vesicles from different mesenchymal stem cell subtypes.
Human mesenchymal stem/stromal cells (MSCs) are found in adult tissues such as bone marrow and are able to differentiate into bone, cartilage and fat tissues. Read more