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We have 100 stem cell PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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stem cell PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 100 stem cell PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Haematopoietic stem cell dysfunction in ageing and disease

Adult organs are maintained by specialised stem cells that persist throughout life thanks to their ability to make exact copies of themselves, all the time retaining the ability to on demand produce the differentiated component cells of the tissue of which they are a part. Read more

Stem Cells: Developing pluripotent stem cell models of inherited retinal diseases

Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide. Read more

Harnessing cell competition to boost tissue repopulation in stem cell therapies

Cell competition is a fundamental biological process akin to natural selection at the cellular level. Through this selection process, cells that are relatively less fit, mis-specified or that harbour some oncogenic mutations are eliminated, and hence called losers, when in proximity of fitter cells, termed winners. Read more

Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more

Studying protein homeostasis in healthy and malignant stem cell development

The Grey lab studies the role of protein homeostasis in healthy and malignant haematopoietic (blood) stem cell development. We focus on the proteome of healthy stem cells as they mature in vivo, expand in vitro and their therapeutic use for bone marrow transplantation. Read more

Accelerated tissue regeneration through direct stem cell re-programming

Project ID. SST9. This project hypothesises that the genetic reprogramming of human mesenchymal stromal cells will lead to enhanced tissue regeneration through the increased production of growth factors, potentially aiding the development of personalised cell therapies. Read more

Identifying novel therapeutic targets in CMML

Chronic myelomonocytic leukaemia (CMML) is a clonal stem cell neoplasm defined by abnormal monocytosis and dysplasia. A quarter of CMML patients progress to acute myeloid leukaemia and these patients have dismal prognosis. Read more

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