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stress PhD Projects, Programmes & Scholarships
We have 143 stress PhD Projects, Programmes & Scholarships
Enabling continuous, personalised stress quantification and management with a wearable system
Project Description. Nine in ten adults in the UK suffer from high or extreme stress in 2023. Stress-related disorders and burnout cost the UK economy more than £28 billion, 23 million sick days, and 165,000 bed days for the National Health Service (NHS) per year [1]. Read more
Hair cortisol, triggers and moderators, and its impact on hair and skin structure and function
Stress is a ubiquitous, pervasive and increasing part of modern life. The impact of chronic stress is far-reaching, and understanding the physiological manifestations of psychological stress is crucial for the development of effective interventions, improving health outcomes, and enhancing overall well-being. Read more
Understanding developmental trajectories underlying the effects of early life stress on neurodevelopment and function
Early Life Stress (ELS) profoundly affects the brain and is a risk factor for the development of psychiatric disorders, which often develop in later life. Read more
Chaperones and the response to protein misfolding stress
Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more
The effect of stress on head and neck cancer patients: laboratory and clinical aspects.
The aim of the lab part of this project is to further investigate. Read more
Unravelling the mechanisms behind plant stress sensing
Agricultural production and food security are severely threatened by the loss of arable land and climate change, with increasingly harsher droughts, floods, and heat waves reducing crop productivity by more than 50%. Read more
Identification of phosphatases that inactivate the endoplasmic reticulum stress sensor Ire1
A self-funded PhD studentship is available in the group of Dr. Martin Schröder in the Department of Biosciences at Durham University to study stress signalling mechanisms originating from the endoplasmic reticulum. Read more
The cellular response to stress: roles in disease and ageing
All living organisms need to adapt to their environment in order to survive and reproduce. They must respond to many stresses including altered oxygen levels, heat or cold, irradiation, infection and injury. Read more
Targeting acute inflammation to reduce coronary artery vein graft failure using bioengineering
The long saphenous vein (LSV) is the most commonly used conduit in cardiac surgery to treat patients with coronary artery disease; however, its use is complicated by high failure rates due to the development of vascular inflammation, intimal hyperplasia (IH) and accelerated atherosclerosis. Read more
Unravelling the Intricacies of Stress Hormone Regulation
Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more
Cellular actions of neurosteroids: implications for post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is a highly debilitating psychiatric disorder that can arise following exposure to at least one traumatic event. Read more
Understanding the stress biology underlying human haematopoietic stem cell adaptation to clinically-relevant ex vivo culture
Project Overview. Haematopoietic Stem Cell (HSC) Gene Therapy (GT) is the only curative option for many monogenic inherited disorders. Read more
Stress grading with novel 2D materials in cable systems rated at transmission voltages
A key pre-breakdown phenomenon in polymer is electrical treeing, which are microscale tree-like hollow channels growing within the solid insulating material. Read more
Self-funded MSc R- Understanding the consequences of unpredictable cold stress events on a beneficial insect and the implications for natural pest control in agricultural landscapes
The earth is currently experiencing rapid changes in climate. As ectotherms, insects are highly susceptible to temperature change, with temperature impacting all aspects of their fitness. Read more
Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia
This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more