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structural biology PhD Projects, Programmes & Scholarships

We have 141 structural biology PhD Projects, Programmes & Scholarships

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We have 141 structural biology PhD Projects, Programmes & Scholarships

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Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Genome Diversification in Cancer and Adaptive Immunity

Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more

Combining Synthetic Biology and Modelling to Understand and Predict Evolution

Mutations, and their effects on organismal fitness, lie at the heart of understanding and predicting evolution. Because of its central role in determining evolutionary outcomes, much experimental and theoretical effort has been put into describing the fitness effects of mutations. Read more

Novel strategies for the diagnosis and treatment of snakebites

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

Obtaining an integrated understanding of oncogenic RAS signalling

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Modulation of Protein Function using Molecular Imprinting

Molecularly Imprinted Polymers (MIPs) are simple, elegant biomimetics that incorporate binding sites bearing steric and chemical functionality complementary to a given target. Read more
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Astrocytes as regulators of neuronal autophagy in ageing brain

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more

Enzyme dynamics, design and evolution

A PhD studentship are available to begin in 2022 as part of PREDACTED (. https://cordis.europa.eu/project/id/101021207. ), a European Research Council project based at University of Bristol. Read more

Method development and applications of Electron Paramagnetic Resonance (EPR)

Electron Paramagnetic Resonance (EPR) is a spectroscopic tool used to study systems containing unpaired electrons. EPR has wide ranging applications from materials science and quantum computing to structural biology and (bio)catalysis. Read more

The mechanism of regulation of protein synthesis via eIF2 molecular complexes

Control of protein synthesis is critical for normal metabolism, development and responses to stress. One major pathway is called the integrated stress response (ISR) and centres on translational control of the general protein synthesis factor eIF2B via the phosphorylation of eIF2 [1,2]. Read more

Understanding the structural consequences of ribosome specialisation

Protein synthesis by ribosomes (translation) and its regulation is essential to life. While it has been traditionally thought that ribosomes were not involved in the regulation of translation, it is now becoming clear that they do contribute. Read more

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