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We have 5 sumo PhD Projects, Programmes & Scholarships

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sumo PhD Projects, Programmes & Scholarships

We have 5 sumo PhD Projects, Programmes & Scholarships

MSc by Research: How are SUMO substrates selected for modification ?

SUMO has diverse roles in cellular physiology that in most cases are mediated by its ability to interact non-covalently with hydrophobic patches of low sequence complexity known as SUMO Interaction Motifs (SIMs). Read more

Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

Investigating the role of SUMOylation in meiotic recombination and chromosome segregation in Arabidopsis

Post-translational modifications of proteins such as phosphorylation, methylation and acetylation have been extensively studied in eukaryotes and now the Small Ubiquitin modifier (SUMO) is gaining attention for its importance in fundamental biological roles. Read more
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