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We have 45 survival analysis PhD Projects, Programmes & Scholarships
survival analysis PhD Projects, Programmes & Scholarships
We have 45 survival analysis PhD Projects, Programmes & Scholarships
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Utilizing Data Augmentation Techniques for Applying Machine Learning Techniques in Survival Analysis with Limited Data Availability
Introduction. Survival analysis is a subfield of statistics that deals with predicting the duration of time until a specific event occurs, such as the failure of a machine, occurrence of a disease, or death of a patient. Read more
Unlocking Insights from Real-World Evidence: Exploring the Safety of Drug Combinations (NDORMS 2024/2)
Adverse drug reactions (ADRs) are unintended, harmful events attributed to the use of medicines. In modern healthcare, ADRs pose a significant challenge due to the complexity of therapeutics, an aging population, and rising multimorbidity. Read more
Using routine programmatic data to estimate trends in HIV incidence and evaluate the impact of interventions for achieving HIV elimination among people who inject drugs
International efforts to eliminate HIV/AIDS by 2030 are failing high-risk populations, particularly people who inject drugs (PWID), who frequently have high HIV prevalence[1]. Read more
Investigation into inflammatory drivers in congenital heart disease
Background. Birth defects are complex developmental phenotypes affecting ~6% of births worldwide. Congenital heart disease (CHD), accounting for 1/6th of these defects is still not fully understood, with the role of inflammation and the contribution of inflammatory cells in disease progression still to be elucidated. Read more
Investigating cause-specific hospitalisations among people living with HIV on antiretroviral therapy
This project aims to investigate rates of hospitalisations due to different causes among people with HIV on antiretroviral therapy, and how they differ by subgroups, for example, by gender or age. Read more
Imaging-based analysis of signalling pathways triggered by immune checkpoint receptors
Commercial partner: Gilead Sciences (Oxford). Read more
How does SUMOylation regulate cell survival and death in Heat Shock Response?
Heat shock response (HSR) is a universally existing essential phenomenon for all living organisms to survive sudden increases in environmental temperature that have pronounced damaging effects on important cellular structures and functions (1). Read more
Epigenetic control of transcription factor regulation of adult neurogenesis in the dentate gyrus
In the adult brain, new neurons are continuously generated in the hippocampal dentate gyrus (DG). This neurogenesis process is highly regulated and consists of cell proliferation, neuronal differentiation, neuronal maturation and survival. Read more
Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier.
Background. Pancreatic cancer is the deadliest of the common cancers. Five-year survival remains low at 10%. Sadly for 80% of patients, by the time their cancer is diagnosed it has spread to distant organs making them ineligible for potentially curative surgery. Read more
Integrative data analysis: from novel biomarker-drug response associations to predicting effective drug combinations
Research Group:
Translational Tumour Biology
More than 140 children with cancer die in Australia each year due to the occurrence of resistance to traditional chemotherapy. To improve overall survival rates for high-risk paediatric cancer patients, the Children’s Cancer Institute initiated the Zero Childhood Cancer national personalised medicine trial (PRISM). Read more
A systems biology analysis of thioredoxin reductase inhibition to support discovery of a novel antifungal treatment
Fungal diseases affect approximately 1.2 billion individuals worldwide with at least 1.5 million deaths each year. The emergence of resistant strains made clinical treatment failures more frequent. Read more
Bio-photonics analysis of biological tissues for in-vivo robot assisted gastric cancer diagnosis
Gastric Cancer is the fifth most common malignancy in the world and third leading cause of death. It has claimed 865,000 lives worldwide in 2017, 12 lives/day in the UK (2016-2018). Read more
Utilising administrative data to inform FIT-guided suspected colorectal cancer referrals of symptomatic patients
Commercial partner: Alpha Laboratories Ltd. Colorectal cancer (CRC) is the third leading cause of cancer death worldwide. In the UK, around 43,000 new CRC cases are recorded annually, and its comparatively high incidence and mortality represent a considerable public health burden. Read more
Developing a pre-clinical human pancreatic cancer model to test novel immunotherapies.
Background. Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers in humans. There is a high unmet medical need to develop new therapies for the treatment of this disease. Read more
Modulation of the Hippo signalling pathway to enhance cardiac regenerative capacity
Common heart diseases such as heart failure (HF) and coronary heart disease (CHD) are characterized by cardiomyocyte loss due to necrosis and apoptosis. Read more
