EPSRC Centre for Doctoral Training in Chemical Synthesis
EPSRC - Engineering and Physical Sciences Research Council EPSRC Centre for Doctoral Training in Chemical Synthesis View All CDTs The EPSRC CDT in Chemical Synthesis is a well-established research centre based in the School of Chemistry, University of Bristol.
Synthesis of ribonucleosides using biocatalytic cascades
Prof N Turner, Prof S Flitsch
Applications accepted all year round
Background – Current state of the art for the synthesis of Anti-Sense Oligonucleotides employs solid phase synthesis. The ASOs are assembled from individual ribonucleotides which themselves are often requiring complicated multistep routes to prepare.