t PhD Projects, Programs & Scholarships

Control of mucosal immunity and barrier function by human gamma/delta T cells

Cardiff University Cardiff School of Medicine

Summary. γδ T cells are ’unconventional’ lymphocytes that regulate immune responses to infection and promote mucosal protection. Read more

Supervisor: Prof M Eberl

23 November 2020 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Understanding how oxygen controls the fate and function of T cells

Babraham Institute (Cambridge) The Babraham Graduate Programme

(Please contact the Group Leader proposing this project directly BEFORE submitting your application to the University of Cambridge Graduate Portal to discuss possible funding options). Read more

Supervisor: Dr S Ross

3 December 2020 PhD Research Project Funded PhD Project (European/UK Students Only)

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Asymmetric fates: can autophagy rejuvenate memory by regulating T cell diversity? (KTPS-NC-12)

University of Oxford Kennedy Institute of Rheumatology

Research Group: Kennedy Trust Non-Clinical Studentships

Efficient T cell responses rely on diversity, characterized by the rise of effector and memory cells1. During ageing, the immune system gradually loses its capacity to generate heterogeneity. Read more

Supervisors: Prof K Simon, Dr A Gérard

8 January 2021 PhD Research Project Funded PhD Project (Students Worldwide)

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Identification of key determinants affecting the quality of human Cancer specific cytotoxic T cells

University of Oxford Radcliffe Department of Medicine

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting Cytotoxic T cells in controlling cancer development. Read more

Supervisor: Prof T Dong

8 January 2021 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Identification of key determinants affecting the quality of human Cancer specific cytotoxic T cells

University of Oxford Weatherall Institute of Molecular Medicine

The main objective of my group’s research is to focus on the functional aspects of the antigen specific T cells and study the factors affecting Cytotoxic T cells in controlling cancer development. Read more

Supervisor: Prof T Dong

8 January 2021 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Discovering the function of protein isoforms in the immune response by exon editing

Babraham Institute (Cambridge) The Babraham Graduate Programme

CD8 T-lymphocytes provide protection against infection by viruses and bacteria as well as killing malignant cells, but can contribute to inflammation and tissue destruction. Read more

Supervisor: Dr M Turner

3 December 2020 PhD Research Project Funded PhD Project (European/UK Students Only)

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How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function

The University of Manchester Faculty of Biology, Medicine and Health

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state. Read more

Supervisors: Dr K Couper, Prof R K Grencis

Year round applications PhD Research Project Self-Funded PhD Students Only

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GW4 BioMed MRC DTP PhD studentship - Automated T-cell expansion in an integrated bioelectronics microfluidic chip: paving the way for personalised T-cell therapies for blood cancer

University of Bath Department of Chemical Engineering

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 17 studentships for entry in October 2021. Read more

Supervisor: Dr M Di Lorenzo

23 November 2020 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Hedgehog signalling in unconventional T cells

University of Cambridge Cancer Research UK Cambridge Institute

The Cancer Research UK Cambridge Institute (CRUK CI) is a joint venture between the Charity, Cancer Research UK, and the University of Cambridge. Read more

Supervisor: Dr M de la Roche

15 November 2020 PhD Research Project Funded PhD Project (Students Worldwide)

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Gene correlation network showing differences in gene expression of effector T cells derived from the bone marrow or peripheral tissues affected by GVHD.

University of Oxford Radcliffe Department of Medicine

Our group is interested in developing novel immunotherapeutic approaches for leukaemia. Clinical approaches currently used include allogeneic haematopoietic stem cell transplantation, chimeric antigen receptor T cell therapy and immune checkpoint inhibitors. Read more

Supervisor: Prof R Chakraverty

8 January 2021 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Gene correlation network showing differences in gene expression of effector T cells derived from the bone marrow or peripheral tissues affected by GVHD.

University of Oxford Weatherall Institute of Molecular Medicine

Our group is interested in developing novel immunotherapeutic approaches for leukaemia. Clinical approaches currently used include allogeneic haematopoietic stem cell transplantation, chimeric antigen receptor T cell therapy and immune checkpoint inhibitors. Read more

Supervisor: Prof R Chakraverty

8 January 2021 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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What is the role of endoplasmic reticulum (ER) stress in the function of innate-like lymphocytes?

University of Oxford Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences

Liye Chen. https://www.ndorms.ox.ac.uk/team/liye-chen. Paul Bowness. https://www.ndorms.ox.ac.uk/team/paul-bowness. Cellular stress has been implicated in many inflammatory processes including the pathogenesis of Ankylosing Spondylitis and related Spondyloarthritides. Read more

Supervisors: Dr L Chen, Prof P Bowness

8 January 2021 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Extremal Combinatorics on Permutations

Queen Mary University of London School of Mathematical Sciences

Research Group: Combinatorics

The School of Mathematical Sciences of Queen Mary University of London invite applications for a PhD project commencing in September 2020 for self-funded students. Read more

Supervisor: Dr JR Johnson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Suppression of T cell immunity and antibody production during virus infection and sepsis

Cardiff University Cardiff School of Medicine

Summary. The generation of protective antibodies against virus infections is critically dependent on help from CD4+ T follicular helper (TFH) cells which are elicited in response to viruses, such as influenza and SARS CoV-2. Read more

Supervisors: Dr J McLaren, Prof M Eberl

23 November 2020 PhD Research Project Competition Funded PhD Project (UK Students Only)

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T-cell Biology

University of Oxford Radcliffe Department of Medicine

Our focus has been on the cell biology of the T-cell surface. Read more

Supervisor: Prof S Davis

8 January 2021 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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