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t PhD Projects, Programs & Scholarships

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  PhD In Infection & Immunity - Profiling superantigen-induced immunosupression of unconventional T cells during severe sepsis
Cardiff University Cardiff School of Medicine
  Dr J McLaren, Prof M Eberl, Prof D Price
Application Deadline: 27 February 2019
Sepsis is a life-threatening illness that is triggered by an exaggerated immune response to severe infection. This unbalanced reaction induces hyperinflammation, shock and organ dysfunction that forms the primary cause of death in hospitalised patients.
Details
Type/Funding
  MRC DiMeN Doctoral Training Partnership: Harnessing T cells to target brain metastases
University of Leeds MRC DiMeN Doctoral Training Partnership
  Dr M Lorger, Dr R Salmond, Prof J Newton-Bishop
Application Deadline: 21 January 2019
An MRC-funded PhD student position is available to explore how T cells can be harnessed to enhance the efficacy of immune checkpoint inhibitors in melanoma brain metastases.
Details
Type/Funding
  Understanding how tetraspanins and the ‘molecular scissor’ ADAM10 promote blood cancer
University of Birmingham School of Biosciences
  Dr M Tomlinson, Dr F L Khanim
Application Deadline: 20 January 2019
Steve Briddon (University of Nottingham) 3rd supervisor. Nick Holliday (University of Nottingham) 4th supervisor. Introduction. T-cell acute lymphoblastic leukaemia (T-ALL) is an aggressive blood cancer that is in urgent need of more effective therapies.
Details
Type/Funding
  Targeting The Thymus To Improve Immune Recovery Following Stem Cell Transplantation For Cancer Treatment
University of Birmingham Institute of Immunology and Immunotherapy
  Prof G Anderson, Dr W Jenkinson
Applications accepted all year round
Background. The treatment of cancer frequently requires the transplantation of bone marrow to regenerate the immune system that is damaged following ablative therapy.
Details
Type/Funding
  Exploring the influence of treatment on CD4+ T-cell sub-populations in patients receiving biologic drugs for their inflammatory arthritis
University of Manchester Faculty of Biology, Medicine and Health
  Prof A Barton, Dr D Plant, Dr S Viatte
Applications accepted all year round
Background. Tumour necrosis factor inhibitor (TNFi) therapy is ineffective for approximately 20% of rheumatoid arthritis (RA) patients and there is currently no way to predict which patients will not benefit.
Details
Type/Funding
  Machine Learning and Integrative Approaches in Immunology: Developing machine-learning and mathematical models to understand heterogeneity of response to personalised cancer immunotherapy
University of Oxford Radcliffe Department of Medicine
  Dr H Koohy, Prof V Cerundolo, Prof T Dong, Prof A Simmons
Application Deadline: 26 July 2019
Cancer immunology is an area of cancer research that is gaining tremendous momentum. However, responses to immunotherapy are heterogeneous and patient care could be substantially improved by better understanding of how and why responses to immunotherapeutic approaches vary in different patients.
Details
Type/Funding
  Harvard T.H. Chan School of Public Health Doctoral Programs
Harvard University
Harvard T.H. Chan School of Public Health brings together dedicated experts from every discipline to educate new generations of global health leaders and produce powerful ideas that can transform the lives of people everywhere.
Details
Type/Funding
  Novel drug target validation for treating Diabetes Mellitus (ref: SF18/APP/Soundararajan)
Northumbria University Faculty of Health and Life Sciences
  Dr M Soundararajan
Applications accepted all year round
The important cellular entities responsible for fighting against infections in our body are the T cells. T cells are however also shown to play a central role in the development of autoimmune diseases (AIDs) as “T cell activation hijacking” is the major autoimmune reaction causing mechanism observed in several AIDs.
Details
Type/Funding
  Laser-free high-resolution localisation and dynamics microscopy in controlled complex cellular environments
University of Oxford BBSRC Interdisciplinary Bioscience DTP
  Dr J Bernadino de la Serna, Prof M Booth
Application Deadline: 25 January 2019
Keywords. Superresolution microscopy, live-cell single molecule imaging, cell sensing and remodelling dynamics, T cell Biology, Immunophysics and Immunoengineering.
Details
Type/Funding
  How is fate determined during T cell development, leukemogenesis and responses?
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Dr S. Russell
Applications accepted all year round
Understanding how cell fate programming works will lead to improved diagnostic and therapeutic opportunities for leukemia, and to improved immunotherapies for cancer and infectious disease.
Details
Type/Funding
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