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t cell PhD Projects, Programmes & Scholarships

We have 132 t cell PhD Projects, Programmes & Scholarships

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We have 132 t cell PhD Projects, Programmes & Scholarships

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Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

The effect of hypoxia on T cell membranes

Cell membranes can be thought of as a composite material comprising proteins and lipids. Many different lipids form the mammalian cell plasma membrane and the overall composition (the lipidome) of the membrane dictates its biophysical properties such as fluidity, rigidity and viscosity. Read more

MSc by Research: Regulation of T cell function by SIK3 in viral infection

T cells play critical roles in the host response to viral infection. Activated cytotoxic CD8 T cells are able to kill virally infected cells while CD4 helper cells produce cytokines to maintain the CD8 response and promote antibody production by B cells. Read more

MRC Precision Medicine: Boosting innate T cell responses in colon cancer

  Research Group: Institute of Cancer Sciences
Project summary. The importance of T cells is well established in colorectal cancer, as their abundance in tumours predicts a good outcome in cancer patients. Read more
Last chance to apply

Promoting cancer cell’s antigen presentation for serving as better targets for T cell immunotherapy

Commercial partner: . Oxford Vacmedix UK Ltd (OVM). , Oxford. Cytotoxic T cells (CTLs), which kill tumour cells upon recognition of antigenic peptides presented by the major histocompatibility complex (MHC) on the cell surface, are the goal of precision medicine including immunotherapies. Read more
Last chance to apply

Immune modulation by checkpoint receptor targeting

Commercial partner: . MiroBio Ltd / Gilead Sciences. , Oxford. Signalling by inhibitory co-receptors, also termed immune checkpoint receptors, such as PD-1, reduces T cell function and promotes T cell exhaustion, compromising the immune response to pathogens and cancer cells. Read more
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Mapping of antigens targeted by the SARS-CoV-2 T-cell response to inform future vaccine design

SARS-CoV-2 is the virus that causes COVID-19. It's emergence resulted in a pandemic which has caused significant mortality (1). Multiple vaccines, primarily targeting the SARS-CoV-2 Spike protein, have been developed which protect against severe disease. Read more

4 Year PhD Prize Studentships at the Kennedy Institute

The Kennedy Institute of Rheumatology (www.kennedy.ox.ac.uk) is a world-renowned research institute housed in a state-of-the-art purpose-built research facility. Read more

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