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t cells PhD Projects, Programmes & Scholarships

We have 59 t cells PhD Projects, Programmes & Scholarships

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We have 59 t cells PhD Projects, Programmes & Scholarships

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Understanding the pro- and anti-tumour functions of IFNγ-producing γδ T cells

TO APPLY CLICK 'INSTITUTION WEBSITE' . γδ T cells are a rare population of T cell receptor-expressing cells that function like innate immune cells.γδ T cells consist of several different subtypes that can promote or prevent cancer progression, depending on the cytokines and cytotoxic molecules they express. Read more

Role of tumour directed T cells in smouldering myeloma

The UCL Myeloma and Tumour Immunology groups are seeking a talented and enthusiastic PhD candidate to lead a project to identify and characterise tumour directed T cells in the bone marrow environment of patients with smouldering myeloma. Smouldering myeloma is a pre-cancerous condition that carries a 50% risk (over 5 years) of developing into the bone marrow cancer called multiple myeloma. Read more

Gene correlation network showing differences in gene expression of effector T cells derived from the bone marrow or peripheral tissues affected by GVHD.

Our group is interested in developing novel immunotherapeutic approaches for leukaemia. Clinical approaches currently used include allogeneic haematopoietic stem cell transplantation, chimeric antigen receptor T cell therapy and immune checkpoint inhibitors. Read more

Gene correlation network showing differences in gene expression of effector T cells derived from the bone marrow or peripheral tissues affected by GVHD.

Our group is interested in developing novel immunotherapeutic approaches for leukaemia. Clinical approaches currently used include allogeneic haematopoietic stem cell transplantation, chimeric antigen receptor T cell therapy and immune checkpoint inhibitors. Read more
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Investigation of an uncharacterised, embryonically lethal gene in immune cell development

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more

How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state. Read more

Single-Cell Lineage Mapping of Elite CAR-NK Cells

The advance of chimeric antigen receptor (CAR) technology has been a breakthrough in cancer immunotherapy. However, it is not clear in which subpopulation of immune cells the endowment of CAR will be most effective in treating cancer. Read more

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