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t cell PhD Projects, Programs & Scholarships

We have 142 t cell PhD Projects, Programs & Scholarships

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  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  Using T cells to eradicate cancer
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in immuno-oncology and the development of novel immunotherapeutic approaches for the treatment of cancer.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Developing better biopharmaceuticals using biomolecular simulation and design
  Dr M van der Kamp, Dr C R Pudney, Dr D Cole
Application Deadline: 2 December 2019

Funding Type

PhD Type

This is a CASE studentship, in collaboration with Immunocore (www.immunocore.com), which will include a placement at the company (in Abingdon).
  Dynamics of ribosome synthesis during T-cell activation
  Research Group: Institute of Cell Biology
  Prof D Tollervey, Prof R Zamoyska
Application Deadline: 5 January 2020

Funding Type

PhD Type

Ribosome synthesis plays a major role in cellular metabolism, consuming some ~80% of total transcription. Probably because of these high metabolic demands, ribosome synthesis is tightly linked to cell growth and division and numerous human diseases have been linked to defects in ribosome synthesis.
  Cross presentation of antigens of recombinant overlapping peptides to optimise vaccines against tumour and infectious diseases
  Dr S Jiang, Dr N Burgess-Brown
Application Deadline: 4 December 2019

Funding Type

PhD Type

THE PROJECT. We have developed a technology to producing overlapping peptides - bacterial expression of an amino acid sequence corresponding to overlapping peptide sequences spanning the length of a protein of interest interspersed with enzymatic cleavage sites.
  New approaches to glycan-based viral vaccine design
  Prof Q Sattentau
Application Deadline: 10 January 2020

Funding Type

PhD Type

Glycosylation is one of the most common post-translational protein modifications, and has been harnessed by many pathogens to evade the adaptive immune response.
  (MCRC Non-Clinical) Exploiting ERK5-signalling to modify T-cell behaviour during tumour progression and radiotherapy response: a new immunotherapy approach?
  Dr K Finegan, Dr J Honeychurch, Prof K Williams, Prof T Illidge
Application Deadline: 1 December 2019

Funding Type

PhD Type

Project summary. ERK5 is a signalling protein that enables cells to transduce extracellular signals into responses. It is expressed in all tissues and is up-regulated in tumours.
  Exploiting tumour-promoting paracrine signals in solid cancers to turbocharge genetically redirected T cells
  Dr A Hurlstone, Prof R Edmondson
Applications accepted all year round

Funding Type

PhD Type

Adoptive cell therapy (ACT) using tumour infiltrating lymphocytes (TILs) or genetically redirected T cells are some of the most promising approaches to emerge recently for the treatment of metastatic disease.
  EASTBIO Antimicrobial peptide signalling to CD8+ T cells
  Dr E Gwyer Findlay, Dr M Swamy
Application Deadline: 5 January 2020

Funding Type

PhD Type

CD8+ T cells are essential for robust immune responses to pathogens, particularly in the intestine. We are interested in how antimicrobial peptides – released from neutrophils and mucosal epithelial cells – affect the differentiation of, and cytokine production by, CD8+ T cells.
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