This project is one of a number that are in competition for funding from the GW4 BioMed2 MRC Doctoral Training Partnership which is offering up to 21 studentships for entry in September 2025. Read more
Autism spectrum disorders (ASDs) are increasingly common developmental disabilities, but they are not well understood. We therefore study the most common monogenetic disorder Neurofibromatosis type 1 (NF1) which affects 1/2600. Read more
Abnormal filamentous inclusions of the proteins amyloid-beta, tau and alpha-synuclein characterise multiple human neurodegenerative diseases, which are called beta-amyloidoses, tauopathies and synucleinopathies, respectively. Read more
The long-established RHUL ATLAS group is renowned for its expertise in physics (Higgs, top quark and exotic signatures involving electrons), statistical methods as well as trigger and data acquisition systems. Read more
Alzheimer's disease (AD) is characterised by chronic progressive loss of neurons and microglial activation, leading to severe functional impairment. Read more
Commercial partner: CFDX Ltd . Neurodegenerative diseases are the 7th leading cause of death globally, and the number one cause of mortality in the UK. Read more
Neurodegenerative diseases are one of the greatest health challenges facing our society. This large group of diseases is characterised by the pathological assembly of specific proteins into filaments in the central nervous system. Read more
TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more
Neuroinflammation is an important driving mechanism in all diseases caused by frontotemporal lobar degeneration, and predicts clinical progression. Read more
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