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We have 5 telomere PhD Projects, Programmes & Scholarships

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telomere PhD Projects, Programmes & Scholarships

We have 5 telomere PhD Projects, Programmes & Scholarships

Untangling how Shelterin safeguards telomere structure and stability - one molecule at a time

Background. Telomeres solve two problems with linear chromosomes. the end-replication problem, DNA loss from the end of chromosomes every replication cycle; and the end-protection problem, protection of the chromosome ends to prevent chromosome fusions. Read more

Nuclear and transcriptional dysregulations during cellular senescence

Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more
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