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telomere PhD Projects, Programs & Scholarships

We have 16 telomere PhD Projects, Programs & Scholarships

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  Characterising mechanisms that control Marek's Disease Virus genome release from telomeres during reactivation from latency
  Dr N J Royle, Dr R Badge
Application Deadline: 6 January 2019
Infection by Marek’s Disease Virus (MDV) is followed by latency, T-cell lymphomas and reactivation. It has significant deleterious effects on chicken health and welfare, with an annual estimated loss close to $2 billion to the global poultry meat and egg production industries.
  Telomere dynamics, stress and aging in an extremophile fish.
  Dr K Dasmahapatra, Dr M E Pownall
Application Deadline: 7 January 2019
Stress may affect the health and lifespan of individuals by shortening telomeres,. which in turn induces chromosomal instability.
  Role of telomere attrition in pancreatic beta cell dysfunction
  Dr J Buxton, Dr N Hill
Applications accepted all year round
Type 2 diabetes (T2D) is a complex condition caused by a myriad of interacting genetic and lifestyle factors. The risk of developing T2D is also strongly influenced by increasing age.
  Understanding and targetting telomere maintenance in cancer
  Dr D Clynes, Dr A Blackford, Dr R Gibbons
Application Deadline: 11 January 2019
Cancer occurs through the uncontrolled growth and division of cells, which eventually leads to the development of a tumour. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes.
  Testing the trade-off between somatic maintenance and reproductive investment as driver of ageing with long-lived predator owls facing variable environmental conditions.
  Prof X Lambin
Applications accepted all year round
How many offspring to produce, how often to reproduce and over how many years are key life history traits that describe the rate of living of organisms [1].
  Targeting telomere maintenance pathways in cancer
  Dr D Clynes, Dr A Blackford
Application Deadline: 11 January 2019
Cancer occurs through the uncontrolled division of cells. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes called telomeres.
  PhD in Cancer Research - Investigating the roles of PARP and ligase inhibitors in preventing escape from telomere crisis.
  Prof D Baird
Application Deadline: 28 February 2019
Telomere crisis (TC) is a natural defence mechanism against cancer. TC happens when the ends of human chromosomes, called telomeres, start to abnormally join with each other, causing cells to die.
  Trans-generational effects of age
  Dr J Schroeder
Application Deadline: 31 December 2018
Inheritance can occur via non-genetic, yet heritable, mechanisms. The resulting trans-generational effects can influence how selection acts and traits evolve.
  Investigating the modulation of cellular responses as a consequence of long term Poly ADP Ribose Polymerase (PARP) inhibition therapy
  Dr T Gaymes
Applications accepted all year round
Approximately 30 years ago, Poly ADP Ribose Polymerase (PARP) activity was shown to play a critical role in the processes of DNA repair in nucleated cells.
  The Role of E3 Ligases on the Modulation of Recombination in Cereals
  Dr I Colas, Dr L Ramsay, Prof R Waugh
Application Deadline: 5 January 2019
Summary. In barley and wheat substantial proportions of the chromosomes are inherited together as a large linkage block, preventing the generation of novel gene combinations and useful variation that could be exploited in breeding programs.
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