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telomere PhD Projects, Programs & Scholarships

We have 11 telomere PhD Projects, Programs & Scholarships

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  The genetic contribution of biological age differences in disease risk
  Dr C Nelson, Prof F Dudbridge, Dr V Codd
Application Deadline: 27 January 2019
Telomere length (TL) is reflective of cellular age, shortens over time and is proposed as a marker of biological age. Here in Leicester we are measuring mean Leucocyte Telomere Length (LTL) in all 500,000 individuals participating in UK Biobank, these exciting data will be used for this project.
  Investigating the effect of telomere length on endothelial cell function
  Dr V Codd, Prof NJ Samani
Application Deadline: 27 January 2019
Telomeres are protein bound DNA repeat structures at the ends of eukaryotic chromosomes, Telomere length (TL) has been proposed as a marker of biological ageing and shorter TL associates with several age related diseases, including coronary artery disease (CAD).
  Role of telomere attrition in pancreatic beta cell dysfunction
  Dr J Buxton, Dr N Hill
Applications accepted all year round
Type 2 diabetes (T2D) is a complex condition caused by a myriad of interacting genetic and lifestyle factors. The risk of developing T2D is also strongly influenced by increasing age.
  Understanding and targetting telomere maintenance in cancer
  Dr D Clynes, Dr A Blackford, Dr R Gibbons
Application Deadline: 26 July 2019
Cancer occurs through the uncontrolled growth and division of cells, which eventually leads to the development of a tumour. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes.
  Testing the trade-off between somatic maintenance and reproductive investment as driver of ageing with long-lived predator owls facing variable environmental conditions.
  Prof X Lambin
Applications accepted all year round
How many offspring to produce, how often to reproduce and over how many years are key life history traits that describe the rate of living of organisms [1].
  PhD in Cancer Research - Investigating the roles of PARP and ligase inhibitors in preventing escape from telomere crisis.
  Prof D Baird
Application Deadline: 28 February 2019
Telomere crisis (TC) is a natural defence mechanism against cancer. TC happens when the ends of human chromosomes, called telomeres, start to abnormally join with each other, causing cells to die.
  Studentships in Precision Medicine
The University of Leicester College of Life Sciences offers six PhD studentships in collaboration with the Leicester Precision Medicine Institute (LPMI), Leicester Biomedical Research Centre (LBRC), Leicester Diabetes Centre (LDC) and the Department of Cardiovascular Sciences (CVS).
  MRC DiMeN Doctoral Training Partnership: Understanding the genetics of melanoma by studying heritable risk factors
  Dr MM Iles, Prof T Bishop
Application Deadline: 21 January 2019
Background. Melanoma is the fifth most common cancer in the UK and its incidence has risen faster than any other common cancer - a five-fold increase since 1975.
  Linking Personality to Ageing in a wild bird.
  Dr P Bize, Dr J Martin
Applications accepted all year round
Understanding the causes of individual variation in the rate of ageing is a major topic in gerontology and evolutionary biology with clear application to human health.
  MYBL2 in blood cancer development and breast cancer
  Dr P Garcia
Applications accepted all year round
Our research interest is to understand the molecular mechanisms that maintain genome integrity in stem cells (both adult and embryonic stem cells) and how loss of genome stability leads to development of cancer specifically blood cancers and breast cancer.
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