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telomeres PhD Projects, Programs & Scholarships

We have 11 telomeres PhD Projects, Programs & Scholarships

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  Characterising mechanisms that control Marek's Disease Virus genome release from telomeres during reactivation from latency
  Dr N J Royle, Dr R Badge
Application Deadline: 6 January 2019
Infection by Marek’s Disease Virus (MDV) is followed by latency, T-cell lymphomas and reactivation. It has significant deleterious effects on chicken health and welfare, with an annual estimated loss close to $2 billion to the global poultry meat and egg production industries.
  Understanding the function of ATRX in the alternative lengthening of telomeres (ALT) pathway
  Research Group: Biomedical Sciences Research Centre
  Dr H Ferreira
Application Deadline: 7 January 2019
Part of what makes cancer cells so dangerous is their ability to divide, uncontrolled, forever. This requires them to prevent their telomeres (chromosome ends) from becoming too short, which would result in cell death.
  Understanding and targetting telomere maintenance in cancer
  Dr D Clynes, Dr A Blackford, Dr R Gibbons
Application Deadline: 11 January 2019
Cancer occurs through the uncontrolled growth and division of cells, which eventually leads to the development of a tumour. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes.
  Trans-generational effects of age
  Dr J Schroeder
Application Deadline: 31 December 2018
Inheritance can occur via non-genetic, yet heritable, mechanisms. The resulting trans-generational effects can influence how selection acts and traits evolve.
  Role of telomere attrition in pancreatic beta cell dysfunction
  Dr J Buxton, Dr N Hill
Applications accepted all year round
Type 2 diabetes (T2D) is a complex condition caused by a myriad of interacting genetic and lifestyle factors. The risk of developing T2D is also strongly influenced by increasing age.
  Targeting telomere maintenance pathways in cancer
  Dr D Clynes, Dr A Blackford
Application Deadline: 11 January 2019
Cancer occurs through the uncontrolled division of cells. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes called telomeres.
  PhD in Cancer Research - Investigating the roles of PARP and ligase inhibitors in preventing escape from telomere crisis.
  Prof D Baird
Application Deadline: 28 February 2019
Telomere crisis (TC) is a natural defence mechanism against cancer. TC happens when the ends of human chromosomes, called telomeres, start to abnormally join with each other, causing cells to die.
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 11 January 2019
It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Telomere dynamics, stress and aging in an extremophile fish.
  Dr K Dasmahapatra, Dr M E Pownall
Application Deadline: 7 January 2019
Stress may affect the health and lifespan of individuals by shortening telomeres,. which in turn induces chromosomal instability.
  Linking Personality to Ageing in a wild bird.
  Dr P Bize, Dr J Martin
Applications accepted all year round
Understanding the causes of individual variation in the rate of ageing is a major topic in gerontology and evolutionary biology with clear application to human health.
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