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telomeres PhD Projects, Programs & Scholarships

We have 8 telomeres PhD Projects, Programs & Scholarships

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  Understanding and targetting telomere maintenance in cancer
  Dr D Clynes, Dr A Blackford, Dr R Gibbons
Application Deadline: 26 July 2019
Cancer occurs through the uncontrolled growth and division of cells, which eventually leads to the development of a tumour. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes.
  Role of telomere attrition in pancreatic beta cell dysfunction
  Dr J Buxton, Dr N Hill
Applications accepted all year round
Type 2 diabetes (T2D) is a complex condition caused by a myriad of interacting genetic and lifestyle factors. The risk of developing T2D is also strongly influenced by increasing age.
  PhD in Cancer Research - Investigating the roles of PARP and ligase inhibitors in preventing escape from telomere crisis.
  Prof D Baird
Application Deadline: 28 February 2019
Telomere crisis (TC) is a natural defence mechanism against cancer. TC happens when the ends of human chromosomes, called telomeres, start to abnormally join with each other, causing cells to die.
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 26 July 2019
It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Linking Personality to Ageing in a wild bird.
  Dr P Bize, Dr J Martin
Applications accepted all year round
Understanding the causes of individual variation in the rate of ageing is a major topic in gerontology and evolutionary biology with clear application to human health.
  Testing the trade-off between somatic maintenance and reproductive investment as driver of ageing with long-lived predator owls facing variable environmental conditions.
  Prof X Lambin
Applications accepted all year round
How many offspring to produce, how often to reproduce and over how many years are key life history traits that describe the rate of living of organisms [1].
  Investigating the effect of telomere length on endothelial cell function
  Dr V Codd, Prof NJ Samani
Application Deadline: 27 January 2019
Telomeres are protein bound DNA repeat structures at the ends of eukaryotic chromosomes, Telomere length (TL) has been proposed as a marker of biological ageing and shorter TL associates with several age related diseases, including coronary artery disease (CAD).
  The genetic contribution of biological age differences in disease risk
  Dr C Nelson, Prof F Dudbridge, Dr V Codd
Application Deadline: 27 January 2019
Telomere length (TL) is reflective of cellular age, shortens over time and is proposed as a marker of biological age. Here in Leicester we are measuring mean Leucocyte Telomere Length (LTL) in all 500,000 individuals participating in UK Biobank, these exciting data will be used for this project.
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