The cellular quality-control process of mitophagy, entailing selective degradation of defective mitochondria (following damage to their DNA) by the process of autophagy, has attracted considerable research interest. Read more
Heart failure is the most common cause of mortality in diabetes patients, but current diabetes therapies have a limited impact on the incidence of heart failure in diabetic populations. Read more
Development of systems for the generation of red blood cells (RBCs) from stem cell sources (adult peripheral blood, cord blood and induced pluripotent stem… Read more
Mitochondrial optic neuropathies result in blindness and are currently untreatable. They arise as a consequence of genetic mutations in either mitochondrial or nuclear DNA and share the common characteristic of primarily affecting retinal ganglion cell (RGC) survival. Read more
At least 40 human disorders, including Huntington disease and myotonic dystrophy, are caused by the expansion of a simple sequence repeat [1]. Read more
Project outline: . The renin angiotensin system (RAS) is a hormonal cascade mediating cardiovascular function. The RAS is key to the development of cardiovascular diseases, including cardiac remodelling in hypertension and heart failure and atherosclerosis. Read more
Chronic myelomonocytic leukaemia (CMML) is a clonal stem cell neoplasm defined by abnormal monocytosis and dysplasia. A quarter of CMML patients progress to acute myeloid leukaemia and these patients have dismal prognosis. Read more
TO APPLY CLICK 'INSTITUTION WEBSITE' . Colorectal cancer (CRC) remains the 2nd most common cancer and 3rd most common cause of cancer-related death globally. Read more
Applications will be reviewed until a suitable candidate is appointed. Galectins are a family of carbohydrate-binding proteins that are commonly over-expressed by many types of cancers such as colorectal, lung, breast, prostate cancer and melanoma. Read more
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