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therapeutic PhD Projects, Programs & Scholarships

We have 237 therapeutic PhD Projects, Programs & Scholarships

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Validation of microRNAs as novel diagnostic and therapeutic targets in ischaemic brain injury
Royal College of Surgeons in Ireland RCSI StAR International PhD Programme Research Projects
Ischaemic stroke is a leading cause of death and most common cause of acquired major disability resulting from death of brain tissue and focal neurological deficits; however, despite decades of research, treatment options remain limited and the lack of therapeutic treatment strategies is a critical clinical problem. Read more
 Supervisor: Dr S Pfeiffer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing dual-mode therapeutic systems to attack cancer tumours
University of York Department of Chemistry
Cancer is a challenging disease target, requiring wide-ranging strategies for intervention. Given the difficulties in treating recalcitrant tumours, multi-mode therapies are of significant potential value. Read more
 Supervisor: Prof D K Smith
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing new models of lung cancer spread to bone to test therapeutic combinations
University of Sheffield Department of Oncology and Metabolism
This project aims to generate novel models that can be used to study how lung cancer spreads to the skeleton and how this can be modified by therapies. Read more
 Supervisors: Prof I Holen, Dr P Ottewell, Dr S Danson, Dr R Young
 1 December 2020  PhD Research Project  Self-Funded PhD Students Only
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Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
The University of Manchester Faculty of Biology, Medicine and Health
Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy. Read more
 Supervisors: Dr J Bruce, Prof K Williams, Dr A P Gilmore
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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USP17 as a cancer therapeutic target
Queen’s University Belfast School of Pharmacy
USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types. Read more
 Supervisor: Dr J Burrows
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Endothelial glycocalyx as a novel therapeutic target in myocardial and renal ischemia reperfusion injuries
University of Bristol Bristol Medical School
Rationale. All the endothelial cells in our body possess a surface glycocalyx (e-GLX)1 which plays a key role in maintaining vascular homeostasis. Read more
 Supervisors: Dr S Satchell, Prof S Suleiman, Dr R Ramnath
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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In vitro assessment of drug sequestration into lysosomes and in silico prediction of implications for drug disposition and therapeutic efficacy
The University of Manchester Faculty of Biology, Medicine and Health
Intracellular concentration of a drug is an important determinant of its efficacy, toxicity, and potential drug-drug interactions [1]. Read more
 Supervisors: Dr A Galetin, Dr D Hallifax
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Small G proteins and their effectors as therapeutic targets in cancer
University of Cambridge Department of Biochemistry
For the majority of cancers the acquisition of invasive and metastatic characteristics leads to incurable disease in the host. Read more
 Supervisor: Dr D Owen
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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High-throughput discovery of combination therapies and engineering of CRISPR/therapeutic proteins
University of Hong Kong School of Biomedical Sciences
Our lab is interested in developing and applying state-of-the-art combinatorial genetics technologies to decipher the mechanisms behind complex diseases, including cancers and neurodegenerative disorders, and discover novel combination therapies. Read more
 Supervisor: Dr A Wong
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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When more yields less: Understanding therapeutic gains according to lesion profile in chronic stroke aphasia.
The University of Manchester Faculty of Biology, Medicine and Health
Aphasia is a common consequence of stoke ultimately affecting one in five cases, with the most common residual difficulty being word finding difficulties, or anomia. Read more
 Supervisors: Dr A Woollams, Dr L Cloutman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding how p18/LAMTOR1 maintains the pulmonary endothelium – a potential therapeutic target for chronic respiratory diseases
Anglia Ruskin University ARU School of Life Sciences
  Research Group: Biomedical Research Group
Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical. Read more
 Supervisor: Dr H Chichger
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating Therapeutic Effect of Different Antioxidants in Friedreich’s Ataxia (FRDA)
Brunel University London Biosciences
Friedreich’s ataxia (FRDA) is an inherited neurodegenerative disorder caused by epigenetic silencing of the frataxin gene. It is the most common inherited ataxia, affecting 1:50,000 Caucasians, and is characterised by neurodegeneration, cardiomyopathy, diabetes mellitus and skeletal deformities. Read more
 Supervisor: Dr S Anjomani-Virmouni
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A key role for FKBPL in the regulation of cancer stem cell signalling and the microenvironment; therapeutic implications for tumour growth and metastasis
Royal College of Surgeons in Ireland RCSI StAR International PhD Programme Research Projects
Cancer stem cells (CSCs) are a special type of cell found within tumours that are able to undergo unlimited self-renewal and are highly resistant to therapy. Read more
 Supervisors: Prof T Robson, Prof D O'Connor
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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RET a novel therapeutic target to treat breast cancer brain metastasis
Royal College of Surgeons in Ireland RCSI StAR International PhD Programme Research Projects
Metastatic disease recurrence occurs in up to 30% of breast cancer patients with approximately 20% of these tumours metastasising to the brain. Read more
 Supervisors: Prof L Young, Dr A Hill
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Diagnostic and therapeutic biomarkers in lung cancer
University of Hong Kong Department of Medicine
The aim of my research laboratory is to develop and implement new ways to improve the prevention, early detection, diagnosis and treatment of lung cancer through multi-disciplinary research that translates results between the laboratory and the clinic. Read more
 Supervisor: Dr D CL Lam
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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