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toxicity PhD Projects, Programs & Scholarships

We have 65 toxicity PhD Projects, Programs & Scholarships

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  Uncovering the mechanisms of cryoprotectant toxicity and improving cryopreservation protocols
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Cryopreservation is the process of placing cells, organs or even whole organisms at low temperatures so that they remain in a state of suspended animation and function is preserved.
  Silver ion-based antimicrobials: mechanisms of toxicity and resistance
  Dr G Mulley, Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"The emergence and persistence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of silver ions.
  Characterising human metalloproteome to disrupt metal toxicity induced neurodegeneration (Ref: SF20/APP/SOUNDARARAJAN)
  Dr M Soundararajan
Applications accepted all year round

Funding Type

PhD Type

Metal accumulation and biometal dyshomeostasis in the nervous system leads to loss of neuronal function.
  Toxicological assessment of electronic cigarette flavours and flavour-derived e-liquid constituents.
  Dr T Marczylo
Application Deadline: 15 June 2020

Funding Type

PhD Type

The initial aims of this project will be a literature review of the toxicity of e-cigarette flavours and then to screen a range of e-cigarette flavours for toxicity using high throughput screening techniques in a suitable in vitro lung model.
  Nanoinjection: a single molecule technique to study amyloid toxicity in neurons
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford, Dr P Actis
Applications accepted all year round

Funding Type

PhD Type

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.
  Protein Misfolding and the Molecular Basis of Alzheimer’s Disease
  Dr J Viles
Applications accepted all year round

Funding Type

PhD Type

Background. World-wide one in three people over the age of 65 will die with Alzheimer’s Disease (AD). The disease is characterised by deposits of amyloid plaques and fibrils of amyloid-beta peptide (Ab) are their main constituent.
  Effect of nanoparticles on cellular conditions in lymphocytes and germ cells in vitro
  Research Group: Chemistry and Biosciences
  Prof D Anderson, Dr M Najafzadeh
Applications accepted all year round

Funding Type

PhD Type

The use of metals such as silver (Ag), gold (Au) and copper (Cu) as nanoparticles (NPs) and other chemicals such as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (Najafzadeh et al., 2016) in medical and lifestyle applications has exponentially increased in recent years, yet little is still known about their impact on DNA and RNA in somatic as well as in germ cells (Habas et al 2018).
  Surface functionalized nanodiamonds for antimicrobial applications
  Prof H Ye, Prof MR Oggioni
Application Deadline: 7 June 2020

Funding Type

PhD Type

Objective. The project is to develop novel surface functionalized nanodiamonds for antimicrobial applications against antibiotic resistant bacteria.
  Carbon nanotubes in the boron neutron capture therapy of cancer
  Dr G Calabrese
Applications accepted all year round

Funding Type

PhD Type

The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes.
  MRC Integrative-Toxicology Training Partnership (ITTP) PhD Studentship Identification of molecular mechanisms of late-occurring cardiotoxicity induced by oncology therapeutics
  Dr J Gill, Dr G Richardson
Application Deadline: 10 July 2020

Funding Type

PhD Type

Number of awards. 1. Start date and duration. October 2020 for 4 years. Overview. Cardiotoxicity is a major complication of cancer chemotherapy, both an acute and frequently late-onset toxicity, occurring months/years after chemotherapy.
  Synthesis and Evaluation of Novel Catechol O-Methyl Transferase Inhibitors (Ref: SF20/APP/TETARD1)
  Dr D Tetard
Applications accepted all year round

Funding Type

PhD Type

Catechol O-Methyl Transferase (COMT) Inhibitors are used as a treatment for Parkinson’s Disease and other neurological disorders but they suffer from significant drawbacks, including toxicity(1,2).
  Development of novel antibody-nanoparticles conjugates (part of the ETN Targeted Anti-Cancer Therapies “TACT”)
  Research Group: Centre for Cancer Research and Cell Biology
  Prof C Scott, Dr K McCloskey
Application Deadline: 1 June 2020

Funding Type

PhD Type

Kadcyla® is an ADC that has been given FDA approval in early 2013 for the treatment of metastatic breast cancer. However, issues with the toxicity of the highly potent payload (e.g.
  Development of a novel therapeutic for the treatment of sickle cell anaemia
  Dr M Brennan, Prof M Devocelle
Applications accepted all year round

Funding Type

PhD Type

Sickle cell anaemia is a chronic condition that is expensive to treat and requires significant clinical intervention and management.
  Role of metal resistance in foodborne bacterial disease
  Dr J Morrissey, Prof J M Ketley
Application Deadline: 7 June 2020

Funding Type

PhD Type

Foodborne infectious diseases are frequent and growing public health problems worldwide (World Health Organisation).
  Chemical pollution and biodiversity: assessing risk to ecosystem services.
  Prof L L Maltby
Applications accepted all year round

Funding Type

PhD Type

Chemicals are a critical part of modern life and a cornerstone of any modern industrial strategy. However, chemicals released into the environment can have adverse effects on biodiversity and the benefits it provide to people (i.e.
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