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toxicity PhD Projects, Programs & Scholarships

We have 63 toxicity PhD Projects, Programs & Scholarships

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  MRC DiMeN Doctoral Training Partnership: Antiretroviral-induced metabolic toxicity: Role of adipose- miRNAs as mechanistic regulators and toxicity biomarkers
  Dr S Pushpakom
Application Deadline: 21 January 2019
Supervisors. Dr S Pushpakom. Prof M Bushell. Prof Sir M Pirmohamed. Background. Diabetes, obesity and cardiovascular disease (collectively called cardiometabolic disease) remain a major public health problem worldwide.
  Assessment of nanomaterial toxicity using alternative, non-rodent models
  Dr H Johnston
Application Deadline: 8 February 2019
The PhD will employ complex 3D in vitro or zebrafish embryo models to assess the toxicity of nanomaterials of varied physico-chemical properties to investigate impacts on the lung, immune system or intestine.
  Chemical cocktails: understanding the combined effects of nanoparticles and pharmaceutical on microbial species and populations.
  Dr I Lynch
Applications accepted all year round
Given that pharmaceuticals and nanomaterials (NMs) used in consumer products such as sunscreens and cosmetics have the same discharge pathways (i.e.
  MRC DiMeN Doctoral Training Partnership: Investigating copper storage in Pseudomonas aeruginosa and its role in pathogenicity
  Prof C Dennison, Dr A De Soyza, Prof C Winstanley
Application Deadline: 21 January 2019
Background. This interdisciplinary project bridges world-leading labs with expertise in bacterial cell biology and infection. Novel therapies are needed to overcome increasing antibacterial resistance.
  Protein Misfolding and the Molecular Basis of Alzheimer’s Disease
  Dr J Viles
Applications accepted all year round
Background. World-wide one in three people over the age of 65 will die with Alzheimer’s Disease (AD). The disease is characterised by deposits of amyloid plaques and fibrils of amyloid-beta peptide (Ab) are their main constituent.
  Why do some DNA sequences poison cells?
  Research Group: BBSRC MIBTP
  Dr D Grainger
Applications accepted all year round
Life on our planet is permitted by an ancient set of instructions encoded by DNA. Consequently, the observation that a cell can be poisoned by its own DNA is completely counterintuitive.
  Surface functionalised nanodiamonds for antimicrobial resistance application
  Prof H Ye, Prof M Oggioni
Application Deadline: 28 January 2019
Antimicrobial resistance (AMR) has been identified as one of the main challenges facing the 21st century, and presents a spectrum of complex and multifaceted questions, ranging in scope from fundamental scientific research at the horizons of disciplines through to the behaviour of individuals and society.
  SiMPLeR: Single-sequence Multi-dimensional Prostate MRI with Deep Learning for enhanced image guided Radiotherapy Treatment
  Dr I Dregely
Applications accepted all year round
First Supervisor. Dr Isabel Dregely. Second Supervisor. Dr M. Jorge Cardoso. The aim of this project is to improve cancer treatment and cure rates through highly individualised radiotherapy by developing next generation image guidance for integration with radiotherapy planning.
  Carbon nanotubes in the boron neutron capture therapy of cancer
  Dr G Calabrese
Applications accepted all year round
The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes.
  Investigating the efficacy of novel antimicrobial mixes on microorganisms, surfaces and cells lines; an integrated study
  Dr A Kelly, Dr S Schwikkard, Prof D Wertheim
Applications accepted all year round
The projection that within 50 years there will be more deaths from antimicrobial resistance than through cancer highlights the continual need for mining new and novel antimicrobials with activity against planktonic microbes and biofilms alike1.
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