toxicity PhD Projects, Programs & Scholarships

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Cryopreservation is the process of placing cells, organs or even whole organisms at low temperatures so that they remain in a state of suspended animation and function is preserved.

Silver ion-based antimicrobials: mechanisms of toxicity and resistance

University of Reading
School of Biological Sciences

Dr G Mulley, Prof S C Andrews

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

"The emergence and persistence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of silver ions.

Characterising human metalloproteome to disrupt metal toxicity induced neurodegeneration (Ref: SF20/APP/SOUNDARARAJAN)

Northumbria University
Faculty of Health and Life Sciences

Dr M Soundararajan

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Metal accumulation and biometal dyshomeostasis in the nervous system leads to loss of neuronal function.

Toxicological assessment of electronic cigarette flavours and flavour-derived e-liquid constituents.

Public Health England
Public Health

Dr T Marczylo

Application Deadline: 15 June 2020

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.

The initial aims of this project will be a literature review of the toxicity of e-cigarette flavours and then to screen a range of e-cigarette flavours for toxicity using high throughput screening techniques in a suitable in vitro lung model.

Nanoinjection: a single molecule technique to study amyloid toxicity in neurons

University of Leeds
Faculty of Biological Sciences

Research Group: Astbury Centre for Structural Molecular Biology

Dr E W Hewitt, Prof S E Radford, Dr P Actis

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.

Protein Misfolding and the Molecular Basis of Alzheimer’s Disease

Queen Mary University of London
School of Biological & Chemical Sciences

Dr J Viles

Applications accepted all year round

Funding Type

PhD Type

Awaiting Funding Decision/Possible External Funding

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This supervisor does not yet know if funding is available for this project, or they intend to apply for external funding once a suitable candidate is selected. Applications are welcome - please see project details for further information.

Background. World-wide one in three people over the age of 65 will die with Alzheimer’s Disease (AD). The disease is characterised by deposits of amyloid plaques and fibrils of amyloid-beta peptide (Ab) are their main constituent.

Effect of nanoparticles on cellular conditions in lymphocytes and germ cells in vitro

University of Bradford
Faculty of Life Sciences

Research Group: Chemistry and Biosciences

Prof D Anderson, Dr M Najafzadeh

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

The use of metals such as silver (Ag), gold (Au) and copper (Cu) as nanoparticles (NPs) and other chemicals such as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (Najafzadeh et al., 2016) in medical and lifestyle applications has exponentially increased in recent years, yet little is still known about their impact on DNA and RNA in somatic as well as in germ cells (Habas et al 2018).

Surface functionalized nanodiamonds for antimicrobial applications

University of Leicester
School of Engineering

Prof H Ye, Prof MR Oggioni

Application Deadline: 7 June 2020

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

Objective. The project is to develop novel surface functionalized nanodiamonds for antimicrobial applications against antibiotic resistant bacteria.

Carbon nanotubes in the boron neutron capture therapy of cancer

Kingston University
Faculty of Science, Engineering and Computing

Dr G Calabrese

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes.

MRC Integrative-Toxicology Training Partnership (ITTP) PhD Studentship Identification of molecular mechanisms of late-occurring cardiotoxicity induced by oncology therapeutics

Newcastle University
Translational and Clinical Research Institute

Dr J Gill, Dr G Richardson

Application Deadline: 10 July 2020

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.

Number of awards. 1. Start date and duration. October 2020 for 4 years. Overview. Cardiotoxicity is a major complication of cancer chemotherapy, both an acute and frequently late-onset toxicity, occurring months/years after chemotherapy.

Synthesis and Evaluation of Novel Catechol O-Methyl Transferase Inhibitors (Ref: SF20/APP/TETARD1)

Northumbria University
Faculty of Health and Life Sciences

Dr D Tetard

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Catechol O-Methyl Transferase (COMT) Inhibitors are used as a treatment for Parkinson’s Disease and other neurological disorders but they suffer from significant drawbacks, including toxicity(1,2).

Development of novel antibody-nanoparticles conjugates (part of the ETN Targeted Anti-Cancer Therapies “TACT”)

Queen’s University Belfast
School of Medicine, Dentistry & Biomedical Sciences

Research Group: Centre for Cancer Research and Cell Biology

Prof C Scott, Dr K McCloskey

Application Deadline: 1 June 2020

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.

Kadcyla® is an ADC that has been given FDA approval in early 2013 for the treatment of metastatic breast cancer. However, issues with the toxicity of the highly potent payload (e.g.

Development of a novel therapeutic for the treatment of sickle cell anaemia

Royal College of Surgeons in Ireland
RCSI StAR International PhD Programme Research Projects

Dr M Brennan, Prof M Devocelle

Applications accepted all year round

Funding Type

PhD Type

Competition Funded PhD Project (Students Worldwide)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

Sickle cell anaemia is a chronic condition that is expensive to treat and requires significant clinical intervention and management.

Role of metal resistance in foodborne bacterial disease

University of Leicester
Department of Genetics and Genome Biology

Dr J Morrissey, Prof J M Ketley

Application Deadline: 7 June 2020

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.

Foodborne infectious diseases are frequent and growing public health problems worldwide (World Health Organisation).

Chemical pollution and biodiversity: assessing risk to ecosystem services.

University of Sheffield
Department of Animal and Plant Sciences

Prof L L Maltby

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Chemicals are a critical part of modern life and a cornerstone of any modern industrial strategy. However, chemicals released into the environment can have adverse effects on biodiversity and the benefits it provide to people (i.e.