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We have 56 toxicity PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
toxicity PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 56 toxicity PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Uncovering the mechanisms of cryoprotectant toxicity and improving cryopreservation protocols
Cryopreservation is the process of placing cells, organs or even whole organisms at low temperatures so that they remain in a state of suspended animation and function is preserved. Read more
Investigating the interplay between the immune consequences of pelvic radiotherapy, the gut microbiome and long-term side-effects (3 year studentship)
The North West has a higher prevalence of pelvic cancers compared to the rest of England. People often present with more locally advanced cancers necessitating treatment which may lead to more long term morbidity. Read more
Investigating the interplay between the immune consequences of pelvic radiotherapy, the gut microbiome and long-term side-effects
The North West has a higher prevalence of pelvic cancers compared to the rest of England. Around 40% of all people with cancer have curative-intent radiotherapy (RT) with 1 in 3 people having pelvic radiotherapy as an important component of their anti-cancer treatment. Read more
Estimating chemical toxicity to wildlife – helping to dispose of our radioactive wastes
We are seeking a highly motivated individual to carry out a 4-year PhD project to develop an approach for estimating chemical toxicity to wildlife in support of the UK’s radioactive waste disposal activities by empowering decision making and building confidence around our ability to deal with radioactive and non-radioactive wastes in the long-term. Read more
Award details iCASE: Looking for an Achilles Heel in the deadly fungi that cause Mucormycosis Ref
Project Summary: Invasive infections by Mucorales fungi are life-threatening complications of severe blast trauma. Mucorales are resistant to most antifungals and cause devastating infections, yet are poorly understood. Read more
PhD opportunities in Pollution Research and Policy
Help shape new policies and regulatory priorities for pollution control and protect human health and the environment from harmful chemical pollution. Read more
Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons
Intraneuronal inclusions known as Lewy bodies are a hallmark of Parkinson’s disease. Amyloid fibrils formed by the misfolding of alpha-synuclein are the principal component of Lewy Bodies. Read more
Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery
Lipid nanocapsules (LNCs) are very interesting nanoformulations as they can be made by phase inversion technique (PIT), a scalable method with predictable particle size at the beginning of the preparation process. Read more
Development of antifungal nanotherapeutics containing AmB+ drug combinations using an advanced continuous manufacturing technology
Each year there are more than 150 million severe cases of fungal infection that occur globally, resulting in significant mortality. Read more
The development of metal-based antibiotics
Background. Due to the widespread rise in microbial resistance, new classes of antimicrobial agents are urgently needed. However, only very few of the compounds in clinical development represent new structural classes. Read more
Investigating the role of SOD1 in sporadic Motor Neuron Disease patients using structural proteomics
Background. Motor Neuron Disease/Amyotrophic lateral sclerosis (ALS) is a complex neurological disorder characterised by the progressive degeneration of motor neurons that is thought to be caused by mitochondrial dysfunction leading to oxidative stress and neuroinflammation. Read more
Modification of antibiotics to improve efficacy / safety
With increasing concern over antibiotic resistance, antibacterial agents such as chloramphenicol and colistin, which have frequently been passed over in the past because of concerns over toxicity, are now becoming more important to tackle resistant bacterial strains. Read more
Carbon nanotubes in the boron neutron capture therapy of cancer
The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes. Read more
Understanding the mechanisms of controlled release systems based on pristine graphene and tripeptides
Graphene has received considerable interest especially in electronics and recently increased attention in the biomedical sciences, with potential applications from gene and drug delivery. Read more
New materials for solar cells
We have a vacancy for a PhD student to work on the synthesis and characterisation of new materials for solar cells. Hybrid lead halide perovskites are attracting considerable interest due to their potential as photovoltaic materials for solar cells with very high efficiencies. Read more