toxicity PhD Projects, Programmes & Scholarships

Chaperones and the response to protein misfolding stress

The University of Manchester Faculty of Biology, Medicine and Health

Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more

Supervisors: Prof C M Grant, Prof M Ashe

Year round applications PhD Research Project Self-Funded PhD Students Only

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Transcriptome biomarkers and mechanisms of chemoresistance

Queen Mary University of London Institute of Dentistry

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni

The University of Manchester Faculty of Biology, Medicine and Health

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year. Read more

Supervisors: Dr J Cavet, Dr D Linton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular characterisation of a novel transporter for the atypical antipsychotic clozapine

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Schizophrenia is a severe psychiatric illness affecting about 24 million people worldwide. Schizophrenia can have a devastating effect on a patient’s life and is associated with increased mortality, with life expectancy reduced on average by 15 years compared to that of the general population. Read more

Supervisors: Dr D Dickens, Prof M Pirmohamed

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring Myxobacteria as live antibiotics against pathogenic bacteria

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

Multi-drug resistant (MDR) bacteria have been identified as a global threat to humanity, limiting therapeutic options. The search for new antibiotics lags far behind the occurrence of MDR bacteria with no new antibiotics brought to the clinic for over 15 years. Read more

Supervisors: Dr P Livingstone, Dr S Maddocks

Year round applications PhD Research Project Self-Funded PhD Students Only

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Adverse Events to Methotrexate in Inflammatory Arthritis: Does Age Matter?

The University of Manchester Faculty of Biology, Medicine and Health

A consistent top-5 research priority for both children and adults with inflammatory arthritis is the tailoring of treatments to prevent or lessen adverse events. Read more

Supervisors: Dr S Shoop-Worrall, Prof K Hyrich, Dr S Verstappen

Year round applications PhD Research Project Self-Funded PhD Students Only

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Towards the development of a novel class of broad-spectrum anti-infective drugs

University of Strathclyde Department of Pure and Applied Chemistry

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Supervisor: Dr FS Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Saving the planet through carbon recycling: engineering bacterial capture of gasified waste for bioplastics production

University of Nottingham School of Life Sciences

Wider context. Climate change caused by the release of greenhouse gases from fossil fuels and through change of land use threatens life on our planet. Read more

Supervisors: Dr K Winzer, Prof N Minton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers

University of Reading School of Pharmacy

Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier. Read more

Supervisors: Dr F Greco, Prof H Osborn

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Greenwich School of Pharmacy (Medway Campus)

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Kent Medway School of Pharmacy

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD in Chemistry: Computer simulation of metal-amyloid interaction and its role in plaque formation

Cardiff University Cardiff School of Chemistry

Alzheimer’s disease is one of the greatest healthcare challenges facing 21st century society. AD is associated with formation of fibrils and plaques in brain tissue that impair proper functioning of neurons. Read more

Supervisor: Prof J Platts

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

University of Leeds Faculty of Medicine and Health

Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more

Supervisor: Prof U Klein

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Inhibiting cell metabolism to enhance tumour cell death

University of Leeds Faculty of Medicine and Health

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Supervisors: Dr S Papa, Dr R Tooze

Year round applications PhD Research Project Self-Funded PhD Students Only

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EPSRC Centre for Doctoral Training in Chemical Biology – Empowering UK BioTech Innovation

Imperial College London Institute of Chemical Biology

Applications to specific research projects are advertised on a rolling basis until the positions have been filled. Candidates will be interviewed by the project supervisors and the CDT directors. Read more

Funded PhD Programme (Students Worldwide) EPSRC Centre for Doctoral Training

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We have 60 toxicity PhD Projects, Programmes & Scholarships

toxicity PhD Projects, Programmes & Scholarships

We have 60 toxicity PhD Projects, Programmes & Scholarships

Chaperones and the response to protein misfolding stress

Transcriptome biomarkers and mechanisms of chemoresistance

Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni

Molecular characterisation of a novel transporter for the atypical antipsychotic clozapine

Exploring Myxobacteria as live antibiotics against pathogenic bacteria

Adverse Events to Methotrexate in Inflammatory Arthritis: Does Age Matter?

Towards the development of a novel class of broad-spectrum anti-infective drugs

Saving the planet through carbon recycling: engineering bacterial capture of gasified waste for bioplastics production

Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

PhD in Chemistry: Computer simulation of metal-amyloid interaction and its role in plaque formation

Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

Cancer: Inhibiting cell metabolism to enhance tumour cell death

EPSRC Centre for Doctoral Training in Chemical Biology – Empowering UK BioTech Innovation

We have 60 toxicity PhD Projects, Programmes & Scholarships

toxicity PhD Projects, Programmes & Scholarships

We have 60 toxicity PhD Projects, Programmes & Scholarships

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