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trafficking PhD Projects, Programmes & Scholarships
We have 31 trafficking PhD Projects, Programmes & Scholarships
MSc by Research: Regulation and mechanics in polarized trafficking
Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more
MScR: Endosomal Trafficking Dysfunction in Astrocytes: A Roadmap to Alzheimer’s disease?
Previously thought of as only a support cell for neurons, astrocytes have now been shown to play an essential role in regulating synaptic activity and regulating transmitter uptake and release. Read more
MSc by Research: Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus
Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more
Exosome biogenesis and organelle trafficking in neurodegeneration.
Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more
MSc by Research: Characterization of the molecular and cellular function of the schizophrenia risk factor CUL9
We invite applications for an exciting MSc Research Project investigating the function of risk factors for neurodevelopmental conditions in membrane trafficking in neurons. Read more
Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury
Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more
Investigating the cellular functions of Trappc9 in brain development and microcephaly
This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more
Regulation of CaaX protein processing
USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types, as well as the migration of a range of cancer cells (NSCLC, breast, ovarian, osteosarcoma). . Read more
Cancer cells ‘feed’ on extracellular matrix components under starvation conditions: how can they do it?
Background. The tumour microenvironment (TME) has a key role in promoting tumour formation and progression. In breast and pancreatic cancers, this accompanied by the accumulation of extracellular matrix (ECM) in the TME. Read more
Cell biology underlying tuberculosis pathogenesis and drug resistance
TB remains the world’s greatest infectious killer despite a vaccine (BCG) for a century and effective antibiotics for 60 years. TB’s persistence over millennia in the face of major medical advances underscores the ability of Mycobacterium tuberculosis to evade and exploit host defences and antibiotics. Read more
Translational Studies into Molecular mechanisms underlying Parkinson's disease
Parkinson’s disease (PD) is a devastating neurodegenerative condition that affects up to 10 million people worldwide and there is no cure. Read more
Optimising Opportunities for Victim Identification in Complex Mass Fatality Incidents
This PhD Scholarship is offered by the newly established Forensic Research Institute (FORRI) at Liverpool John Moores University. Read more
‘Vulnerabilities’ and ‘Capabilities’ within the Context of Protracted Displacement Crises
Whilst the 'vulnerabilities' of refugees and internally displaced persons have been often highlighted and documented over several decades, less is known about the 'capabilities' of displaced people themselves to respond to contexts of exile/displacement. Read more
Developing an advanced microscopy platform to characterise neuronal internalisation and spreading of pathological protein aggregates
Department of Brain Sciences at Imperial. PhD studentship in advanced fluorescence microscopy to study Parkinson’s disease and dementia with Lewy bodies, Imperial College London. Read more
Supply chain digitalisation: building a sustainable supply chain
Supply chain digitalisation has garnered increasing attention in both industry and academia (Wang and Prajogo, 2024, Seyedghorban et al., 2020, Holmström et al., 2019). Read more