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We have 49 trafficking PhD Projects, Programmes & Scholarships

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trafficking PhD Projects, Programmes & Scholarships

We have 49 trafficking PhD Projects, Programmes & Scholarships

Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease

Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway. Read more

MSc by Research: Regulation and mechanics in polarized trafficking

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Exosome biogenesis and organelle trafficking in neurodegeneration.

Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more

MSc by Research: Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus

Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more

Regulation and mechanics in polarity

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Exploring the form and function of vitamin B12

We are seeking a highly motivated individual to join our team as a fully funded PhD student who will investigate the trafficking, delivery, and utilisation of vitamin B12 in both bacteria and eukaryotes. Read more

Regulation of CaaX protein processing

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types, as well as the migration of a range of cancer cells (NSCLC, breast, ovarian, osteosarcoma).    . Read more

Size regulation of intracellular nanovesicles

Eukaryotic cells are compartmentalized. they contain organelles and membrane-bound domains that each have distinct identities. For example, the endoplasmic reticulum is different to the Golgi apparatus. Read more

Cancer cells ‘feed’ on extracellular matrix components under starvation conditions: how can they do it?

Background. The tumour microenvironment (TME) has a key role in promoting tumour formation and progression. In breast and pancreatic cancers, this accompanied by the accumulation of extracellular matrix (ECM) in the TME. Read more

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