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Transcription replication coordination
University of Birmingham Institute of Cancer and Genomic Sciences
RNA Pol II (RNAPII) transcription and DNA replication are the two essential-for-life processes that use as a substrate the DNA in our cells, allowing them to express the content of their genetic information and to propagate these instructions to daughter cells. Read more
 Supervisor: Dr M Saponaro
 Year round applications PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

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Self-Funded PhD Students Only

Self-Funded PhD Students Only

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

More Details
Effect of Mediator on transcriptional bursting
Montreal Clinical Research Institute (IRCM) Experimental Medicine/McGill University
Mediator is a universal transcriptional coactivator (Jeronimo and Robert, 2017; Soutourina, 2018). It is recruited to enhancers by sequence-specific transcription factors and allows communication between the enhancers and their target promoters. Read more
 Supervisor: Dr F Robert
 Year round applications PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

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Funded PhD Project (Students Worldwide)

Funded PhD Project (Students Worldwide)

This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details
Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
University of Cambridge Department of Biochemistry
The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells. Read more
 Supervisor: Prof E D Laue
 Year round applications PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Self-Funded PhD Students Only

Self-Funded PhD Students Only

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

More Details
Prokaryotic transcription: a new direction?
University of Birmingham School of Biosciences
  Research Group: BBSRC MIBTP
In all lifeforms DNA is transcribed to create RNA templates for protein synthesis. This is known as the central dogma of molecular biology. Read more
 Supervisors: Prof DC Grainger, Dr P Grzechnik
 10 January 2021 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (Students Worldwide)

Competition Funded PhD Project (Students Worldwide)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details
Defining the mechanism and biological role of R-loop promoter activity in mammalian gene expression
University of Oxford Sir William Dunn School of Pathology
R-loops are triplex nucleic acids that form when RNA invades double stranded DNA, displacing single strand DNA by forming an RNA:DNA hybrid. Read more
 Supervisor: Prof N J Proudfoot
 8 January 2021 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (Students Worldwide)

Competition Funded PhD Project (Students Worldwide)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details
Prevention of DNA replication and transcription machinery conflict: how do helicases help?
University of York Department of Biology
DNA replication is a crucial process for life. Genomes need to be duplicated in order for cells to divide and organisms to grow. Though the replication process is vital it does not always proceed smoothly. Read more
 Supervisors: Dr M Hawkins, Dr D Barilla
 10 January 2021 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (Students Worldwide)

Competition Funded PhD Project (Students Worldwide)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details
(BBSRC DTP) Development of anti-cancer agents and biomarkers that target intrinsically disordered regions of transcription factors and protein kinases
The University of Manchester Department of Chemistry
The controlled manipulation of transcription factors, protein kinases and protein phosphatases is central to improving our understanding of cellular processes and, importantly, in the development of next-generation therapeutics for a variety of cancers. Read more
 Supervisors: Prof J Waltho, Dr A Almond, Prof A Munro
 31 January 2021 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (Students Worldwide)

Competition Funded PhD Project (Students Worldwide)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details
Effects of transcription on genome stability
University of Bristol School of Biochemistry
Transcription-coupled DNA repair (TCR) pathways prioritise the repair of certain lesions in "active" genes. These pathways help maintain genome integrity throughout the lifetime of multi-cellular organisms, and thus help prevent the occurrence of mutation that might cause cancer or other disorders. Read more
 Supervisor: Prof N J Savery
 Year round applications PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Self-Funded PhD Students Only

Self-Funded PhD Students Only

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

More Details
Transcription factors mediating light input to the Arabidopsis circadian clock
Royal Holloway, University of London School of Biological Sciences
The circadian clock is tightly tied to the light environment. Transcriptional feedback loops are able to generate a self-sustaining rhythm of approximately 24 hours which impinges on almost every aspect of physiology in higher organisms. Read more
 Supervisor: Dr P Devlin
 Year round applications PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Self-Funded PhD Students Only

Self-Funded PhD Students Only

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

More Details
(MRC DTP) Epigenetic regulation of chromatin remodelling driving metastasis in aggressive breast cancers
The University of Manchester Faculty of Biology, Medicine and Health
Breast cancer is the most common and deadliest cancer in women. To classify patients who might benefit from different treatments, pathologists look for the presence of specific proteins including Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal Growth Factor (HER2) receptor. Read more
 Supervisors: Dr S Nagarajan, Dr R Clarke, Prof A Sharrocks
 15 November 2020 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (Students Worldwide)

Competition Funded PhD Project (Students Worldwide)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details
Oncogenic mechanisms causing malignant transformation of lymphoid cells
University of Leeds Faculty of Medicine and Health
Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more
 Supervisor: Prof U Klein
 Year round applications PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Self-Funded PhD Students Only

Self-Funded PhD Students Only

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

More Details
SWBio DTP PhD project: Amyloid Transcription Block Survival - Deriving Functionally Active Peptide Inhibitors of Amyloidosis and Toxicity
University of Bath Department of Biology & Biochemistry
This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP) https://www.swbio.ac.uk/. Read more
 Supervisor: Prof J Mason
 23 November 2020 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (European/UK Students Only)

Competition Funded PhD Project (European/UK Students Only)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

More Details
Structural mechanism of multi-faceted roles of FANCJ in cellular DNA repair, replication and transcription.
University of Leeds Faculty of Biological Sciences
We study the repair mechanism of interstrand crosslinks (ICLs) and double-strand breaks (DSBs), which are highly toxic DNA damages in cells. Read more
 Supervisors: Dr Q. Wu, Prof R.W. Bayliss
 10 January 2021 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (Students Worldwide)

Competition Funded PhD Project (Students Worldwide)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details
NF-kB transcription factors in arterial disease
University of Sheffield Department of Infection, Immunity and Cardiovascular Disease
We are looking for an outstanding, enthusiastic and dynamic graduate scientist to join our laboratory as a PhD Student. We will study the role of the NF-kB transcription factor c-Rel in atherosclerosis, a disease of arteries where the build of fatty plaques causes angina, heart attack or stroke. Read more
 Supervisors: Prof P Evans, Prof S Francis
 23 October 2020 PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Funded PhD Project (European/UK Students Only)

Funded PhD Project (European/UK Students Only)

This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.

More Details
Transcription control and immune evasion in African trypanosomes
Imperial College London Department of Life Sciences
  Research Group: Division of Cell & Molecular Biology
Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify. Read more
 Supervisor: Prof G Rudenko
 Year round applications PhD Research Project

PhD Research Project

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

View All
Competition Funded PhD Project (Students Worldwide)

Competition Funded PhD Project (Students Worldwide)

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.

More Details

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