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transcription PhD Projects, Programmes & Scholarships

We have 69 transcription PhD Projects, Programmes & Scholarships

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We have 69 transcription PhD Projects, Programmes & Scholarships

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Transcription: molecular mechanisms & dynamics

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. For further details. Read more

Coordination between RNAPII transcription and DNA replication

RNA Pol II (RNAPII) transcription and DNA replication are the two essential-for-life processes that use as a substrate the DNA in our cells, allowing the¬¬m to express the content of their genetic information and to propagate these instructions to daughter cells. Read more

Effects of transcription on genome stability

Transcription-coupled DNA repair (TCR) pathways prioritise the repair of certain lesions in "active" genes. These pathways help maintain genome integrity throughout the lifetime of multi-cellular organisms, and thus help prevent the occurrence of mutation that might cause cancer or other disorders. Read more

Understanding the gene regulatory landscape of embryonic stem cells and cancer cells

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity. Read more

Going across temporal scales: how are oscillatory dynamics of protein expression decoded in the expression of downstream genes in neurogenesis?

In recent years, our understanding of gene expression dynamics has been transformed by single-cell, molecular and imaging technologies. It was thought that genes are simply “on” or “off”, but we now appreciate that the dynamics are more complex. Read more

How do individual histone modifications help cells make decisions?

We are looking for a highly-motivated, independent-thinking candidate to undertake a PhD project exploring the role of individual histone modifications in nuclear organisation, regulation of transcription, and the process of stem cell fate decisions. Read more

Laboratory of Gene Regulation

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more

Laboratory of Gene Regulation

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more

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