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  EASTBIO An ancient transcription factor controlling cuticle development and water transport in the liverwort Marchantia polymorpha
  Research Group: Institute of Molecular Plant Sciences
  Dr W J Goodrich, Dr C A Kidner
Application Deadline: 5 January 2020

Funding Type

PhD Type

We identified a basic helix loop helix transcription factor (called ZOU) which is specifically expressed in the endosperm of seed in flowering plants.
  (MRC DTP) Regulatory chromatin and transcriptional networks impacting on embryonic stem cell differentiation
  Prof A Sharrocks, Prof M Rattray
Application Deadline: 15 November 2019

Funding Type

PhD Type

Embryonic stem cells (ESCs) can give rise to all of the cells in the body so a detailed understanding of how they commit to other cell fates is fundamentally important to understanding both normal human developmental processes and how developmental defects arise.
  Going across temporal scales: how are oscillatory dynamics of protein expression decoded in the bursty expression of downstream genes in neurogenesis?
  Prof N Papalopulu, Prof H Ashe
Applications accepted all year round

Funding Type

PhD Type

In recent years, our understanding of gene expression dynamics has been transformed by the application of single cell molecular and imaging technologies.
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
  BBSRC EASTBIO PhD Programme: Uncovering molecular details of regulation of the mRNA capping enzymes in gene expression
  Dr A Pisliakov, Prof V Cowling
Application Deadline: 5 January 2020

Funding Type

PhD Type

This 4 year PhD project is part of a competition funded by EASTBIO BBSRC Doctoral Training Partnership http://www.eastscotbiodtp.ac.uk/how-apply-0.
  Deciphering the impact of non-coding mutations in disease
  Dr N Owens
Application Deadline: 2 December 2019

Funding Type

PhD Type

Lead Supervisor. Dr Nick Owens, College of Medicine and Health, University of Exeter. Additional Supervisors. Dr Sarah Flanagan, College of Medicine and Health, University of Exeter.
  SWBio DTP PhD project: Amyloid Transcription Block Survival - Deriving Functionally Active Peptide Inhibitors of Amyloidosis and Toxicity
  Prof J Mason
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  New ways of terminating transcription in bacterial pathogens
  Dr C Brown
Applications accepted all year round

Funding Type

PhD Type

An excellent PhD candidate (’A’ grades) interested in researching the fundamental process of gene expression in bacteria is being recruited to join a multidisciplinary team led at University of Otago, Dunedin, New Zealand.
  Developmentally regulated expression of the transcription factor PRDM1 in the mouse
  Prof E Robertson
Application Deadline: 10 January 2020

Funding Type

PhD Type

The master transcriptional regulator Blimp-1/PRDM1 contains an N-terminal PR/SET domain and five C2H2 zinc fingers located near its C-terminus that mediate DNA binding, nuclear import, and recruitment of histone modifying enzymes.
  TurboID-charging discovery of plant pathogen virulence and host defense mechanisms (JONESS20DTP)
  Prof J Jones
Application Deadline: 25 November 2019

Funding Type

PhD Type

Plant pathogens cause disease and reduce crop yields, secreting "effector" proteins that target host. proteins and suppress immunity.
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