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translation PhD Projects, Programs & Scholarships

We have 96 translation PhD Projects, Programs & Scholarships

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  PhD Translation

Funding Type

PhD Type

OVERVIEW. Translation is part of the Modern Languages research cluster, which provides a vibrant environment for both disciplinary and interdisciplinary scholarship.
  Adaptation to oxidative stress in hepatitis C virus persistence: the role of IRES-dependent translation.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

Hepatitis C virus (HCV) causes a clinically important disease affecting 3% of the world population (Chan 2014). About 75% of the infection will develop into chronic hepatitis, which can then progress into fibrosis, cirrhosis and hepatocellular carcinoma.
  mRNA translation reprogramming and metabolic re-wiring in response to ribosome-targeted therapies
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Increased synthesis and activity of ribosomes are associated with oncogenesis downstream of the major oncogenes including MYC, RAS and PI3K.
  Interplay between the translation of upstream open reading frames and ribosome nascent chain-associated factors to control gene expression in eukaryotic cells
  Dr M Pool, Prof G D Pavitt
Applications accepted all year round

Funding Type

PhD Type

Eukaryotic mRNAs typically contain one open reading frame that is translated into protein. However many mRNAs contain additional upstream ORFs (uORFs) that regulate protein expression by controlling the flow of ribosomes to the main ORF, often by regulated reinitiation.
  Noisy translation: modelling of stochastic effects on protein production
  Prof C Romano, Prof I Stansfield
Applications accepted all year round

Funding Type

PhD Type

This project will focus on the mathematical modelling of a fundamental process in the cell. translation of the messenger RNA into a protein.
  The role mRNA-specific translation during chronological aging
  Prof C M Grant, Prof M Ashe, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Biological ageing can be thought of as a progressive decline in the ability of an organism to survive stress and disease. It is a complex process which is influenced by both genetic and environmental factors.
  Roles of RNA-binding proteins in subcellular RNA localization and translation in neurons
  Dr M Chekulaeva
Applications accepted all year round

Funding Type

PhD Type

The subcellular localization and translation of mRNAs are fundamental biological processes. They underlie establishment of body axis, cell growth, cell migration, and synaptic plasticity, which serves as a foundations of learning and memory.
  Stress regulation of protein translation: role in cancer and neurodegeneration
  Dr A J Whitmarsh, Prof M Ashe
Applications accepted all year round

Funding Type

PhD Type

Cells are subjected to a range of stresses that include physical injury, changes in oxygen levels or temperature, nutrient deprivation, radiation and infection.
  Scalable big data analytics for healthcare translation
  Dr J Ho
Applications accepted all year round

Funding Type

PhD Type

A range of specific PhD projects can be developed within the broad theme of scalable big data analytics for healthcare translation, including.
  Regulatory roles for ribosome-associated proteins in protein synthesis
  Prof G D Pavitt, Dr M Pool
Applications accepted all year round

Funding Type

PhD Type

Protein synthesis is a highly-conserved, dynamic and tightly controlled process that is central to the activity of all cells. All phases of translation can be controlled.
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