University of East Anglia Featured PhD Programmes
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transplantation PhD Projects, Programs & Scholarships

We have 17 transplantation PhD Projects, Programs & Scholarships

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  The Development of an Artificial Heart
  Prof AW Khir
Applications accepted all year round

Funding Type

PhD Type

Background. Heart failure is defined as the inability of the heart to pump and circulate blood around the body to provide nutrients to the various organs.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Expanded potential stem cells for regenerative medicine, immunotherapy, and biotechnology
  Prof P Liu
Applications accepted all year round

Funding Type

PhD Type

Embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells) are pluripotent and thus hold great promise in regenerative medicine, studying disease mechanisms and drug discovery.
  Anaemia of Chronic Kidney Disease: An All-Wales primary and secondary care prevalence and incidence study
  Prof M Gumbleton
Applications accepted all year round

Funding Type

PhD Type

Aim. The project will investigate the prevalence of ACKD in Wales across primary and secondary care. It will follow patients with CKD G3-5 to explore the association between ACKD and hospitalisation and mortality.
  Novel approaches for the treatment of dry eye disease
  Dr J Gabhann, Prof C Murphy
Applications accepted all year round

Funding Type

PhD Type

Inflammation is a key unifying factor for a range of ocular surface inflammatory diseases including autoimmune mediated dry eye disease (DED) and complications with corneal transplantation (CT).
  Generation of universal donor transplant tissue by genomic engineering of induced pluripotent stem cells
  Dr F Manson, Dr T Wang
Applications accepted all year round

Funding Type

PhD Type

Project Description. Blindness can be caused by mutations in genes expressed in the retinal pigment epithelium (RPE), the tissue adjacent to the rod and cone photoreceptor cells that is essential for their normal function.
  Structure based design of novel warheads for use in peptide-drug conjugates
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round

Funding Type

PhD Type

Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
  The effects of Interleukin-1 primed mesenchymal stem cells on hypoxic-ischemic brain damage
  Dr E Pinteaux, Prof S Allan
Applications accepted all year round

Funding Type

PhD Type

Hypoxic-ischemic brain damage is one of the main causes of death and neurological disability after stroke worldwide.
  Polymeric Hydrogels for Regenerative Medicine Applications
  Dr P De Bank
Applications accepted all year round

Funding Type

PhD Type

Regenerative medicine aims to repair injured or diseased tissues using a multidisciplinary approach to stimulate natural repair mechanisms or promote healing through the transplantation of cells, often the patient’s own stem cells.
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  Genetic studies of corneal endothelial dystrophies and development of alternative treatment options
  Dr M Ali
Applications accepted all year round

Funding Type

PhD Type

The cornea is the protective front part of the eye that provides most of the eyes focusing power. The endothelium is a single-cell layer on the inside of the cornea that maintains fluid balance and is required for corneal transparency.
  Bioengineering of patient-derived explants (PDEs) and 3D organoid culture systems for tissue regeneration, cancer and drug discovery
  Dr A Shams Nateri
Applications accepted all year round

Funding Type

PhD Type

The intestine provides an attractive route to model biologically important intestinal processes and a unique opportunity for the direct identification and analysis of factors that contribute to development and maintenance of both normal as well as the development of neoplasia.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Single Cell Biology of Hematopoietic Stem- and Progenitor Cells in Blood Cancer and Ageing
  Prof Claus Nerlov, Prof P Vyas
Application Deadline: 24 July 2020

Funding Type

PhD Type

The focus of the Nerlov laboratory is to use single cell genomics and functional analysis, combined with advanced mouse genetics, to study the function of hematopoietic stem– and progenitor cells in normal development and during ageing.
  Impact of Inflammatory Signals on the Regenerative, Anti-inflammatory and Immunomodulatory Potential of Human Mesenchymal Stem Cells and their Secretome
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Adult multipotent stem cells can be easily isolated from a variety of adult human tissues and organs including bone marrow and adipose tissue.
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