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"tyrosine" AND "kinases"×
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tyrosine kinases PhD Projects, Programs & Scholarships

We have 8 tyrosine kinases PhD Projects, Programs & Scholarships

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  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  The molecular mechanisms of thrombosis and haemostasis
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

A healthy cardiovascular system relies on the cells lining the blood vessels (endothelial cells) and heart cells (cardiomyocytes) to function normally.
  Targeting the Gas6-TAM receptor signalling pathway in cancer
  Dr S Hafizi
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for a self-funded 3 year full-time PhD project, to commence in October 2019 or February 2020. The PhD will be based in the School of Pharmacy and Biomedical Sciences and will be supervised by Dr Sassan Hafizi.
  Structural biology of the intrinsically disordered protein SH2B1
  Prof M P Williamson
Applications accepted all year round

Funding Type

PhD Type

Signalling between the outside of the cell and the inside uses a complicated network of interacting systems. One common signalling mechanism uses receptor tyrosine kinases.
  Exploring the role of the Protein Tyrosine Phosphatase Receptor- Type F (PTPRF) in focal adhesion dynamics
  Dr H Sharpe
Application Deadline: 3 December 2019

Funding Type

PhD Type

The dynamic and reversible phosphorylation of tyrosine residues is a key feature of intercellular communication. Through the regulated activities of kinases and phosphatases, cells are primed to respond to changes in their environment.
  Neuronal Src kinases: oncogenes in brain development?
  Dr G Evans, Dr S Chawla
Application Deadline: 30 June 2020

Funding Type

PhD Type

The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections.
  Modulation of platelet-mediated innate immune responses in chronic lymphocytic leukaemia
  Dr M Arman
Application Deadline: 31 March 2020

Funding Type

PhD Type

Chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia in the Western World. B-cell receptor-induced intracellular signals are critical for the survival of leukaemia cells and disruption of this pathway by the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib is a highly effective CLL therapy.
  Identifying inhibitors specific to the OPG-kinome: towards novel treatments for Pulmonary Arterial Hypertension (PAH).
  Prof A Lawrie, Dr R Thompson
Applications accepted all year round

Funding Type

PhD Type

Background. Pulmonary arterial hypertension (PAH) is a fatal progressive disease. Median life expectancy in untreated PAH patients is 2.8 years.
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