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ubiquitin PhD Projects, Programs & Scholarships

We have 37 ubiquitin PhD Projects, Programs & Scholarships

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  Mechanisms controlling the biogenesis and functions of chloroplasts in plants: protein transport and the ubiquitin-proteasome system
  Prof P Jarvis
Applications accepted all year round
Our research is focused on the biogenesis of chloroplasts and other plastids in plants, particularly in relation to the import of nucleus-encoded proteins and the role of the ubiquitin-proteasome system.
  Elucidating the Mechanism of Muscle Wasting: The Role of Ubiquitin
  Dr YL Lai, Prof L Holm
Application Deadline: 6 January 2019
The loss of muscle mass and strength, known as muscle “wasting”, primarily results from excessive protein degradation.
  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
  Dr I Dreveny
Applications accepted all year round
Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
  4 Year Wellcome Trust PhD Programme: The role of protein ubiquitylation is controlling a novel innate immune signalling network.
  Prof Sir Philip Cohen
Application Deadline: 14 December 2018
Toll-Like Receptors are activated by substances produced by microbial pathogens, such as lipopolysaccharide (LPS), a component of the cell wall of gram-negative bacteria.
  Regulation of protein degradation and homeostasis by the ubiquitin system
  Dr Y Kulathu
Application Deadline: 31 December 2018
Protein degradation is a fundamental process that is important for timely elimination of damaged proteins. This process relies on modification of proteins with ubiquitin, a signal to target destruction of modified proteins.
  (BBSRC DTP CASE) Understanding how macrophages restore immune health after infection
  Dr G Lopez-Castejon, Dr D Brough
Application Deadline: 31 January 2019
Inflammation is the response of the body to tissue danger.
  Chemical profiling of ubiquitin conjugation enzymes
  Dr S Virdee
Application Deadline: 31 December 2018
A PhD project in the Virdee lab is available involving the development of chemical tools known as activity-based probes (ABPs). ABPs measure the activity of disease-relevant enzymes and the Virdee lab have developed these for the enzymes that conjugate ubiquitin to substrates (1-3).
  Discovery of ubiquitin-conjugation enzyme inhibitors from marine natural products.
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Prof M Auer, Dr N Carragher
Application Deadline: 13 December 2018
Ubiquitination is a key biochemical event which regulates most cell processes. Proteins are modified with ubiquitin, or ubiquitinated, through a series of reactions involving the E1, E2 and E3 enzymes.
  Ubiquitin chain recognition by deubiquitylating (DUB) enzyme complexes
  Research Group: BBSRC White Rose DTP
  Dr E Zeqiraj, Dr D Tomlinson
Application Deadline: 7 January 2019
A studentship to study Ub signalling is available in the laboratories of Dr Elton Zeqiraj and Dr Darren Tomlinson at the University of Leeds.
  The ubiquitin proteasome system and neurodegenerative disease
  Dr L Bedford
Applications accepted all year round
The mechanisms that cause neurones to die in neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases remain unclear.
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