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ubiquitin PhD Projects, Programs & Scholarships

We have 37 ubiquitin PhD Projects, Programs & Scholarships

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  Mechanisms controlling the biogenesis and functions of chloroplasts in plants: protein transport and the ubiquitin-proteasome system
University of Oxford Department of Plant Sciences
  Prof P Jarvis
Applications accepted all year round
Our research is focused on the biogenesis of chloroplasts and other plastids in plants, particularly in relation to the import of nucleus-encoded proteins and the role of the ubiquitin-proteasome system.
Details
Type/Funding
  Elucidating the Mechanism of Muscle Wasting: The Role of Ubiquitin
University of Birmingham School of Sport, Exercise and Rehabilitation Sciences
  Dr YL Lai, Prof L Holm
Application Deadline: 6 January 2019
The loss of muscle mass and strength, known as muscle “wasting”, primarily results from excessive protein degradation.
Details
Type/Funding
  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
University of Nottingham School of Pharmacy
  Dr I Dreveny
Applications accepted all year round
Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
Details
Type/Funding
  4 Year Wellcome Trust PhD Programme: The role of protein ubiquitylation is controlling a novel innate immune signalling network.
University of Dundee School of Life Sciences
  Prof Sir Philip Cohen
Application Deadline: 14 December 2018
Toll-Like Receptors are activated by substances produced by microbial pathogens, such as lipopolysaccharide (LPS), a component of the cell wall of gram-negative bacteria.
Details
Type/Funding
  Regulation of protein degradation and homeostasis by the ubiquitin system
University of Dundee MRC Protein Phosphorylation and Ubiquitylation Unit
  Dr Y Kulathu
Application Deadline: 31 December 2018
Protein degradation is a fundamental process that is important for timely elimination of damaged proteins. This process relies on modification of proteins with ubiquitin, a signal to target destruction of modified proteins.
Details
Type/Funding
  (BBSRC DTP CASE) Understanding how macrophages restore immune health after infection
University of Manchester Faculty of Biology, Medicine and Health
  Dr G Lopez-Castejon, Dr D Brough
Application Deadline: 31 January 2019
Inflammation is the response of the body to tissue danger.
Details
Type/Funding
  Chemical profiling of ubiquitin conjugation enzymes
University of Dundee MRC Protein Phosphorylation and Ubiquitylation Unit
  Dr S Virdee
Application Deadline: 31 December 2018
A PhD project in the Virdee lab is available involving the development of chemical tools known as activity-based probes (ABPs). ABPs measure the activity of disease-relevant enzymes and the Virdee lab have developed these for the enzymes that conjugate ubiquitin to substrates (1-3).
Details
Type/Funding
  Discovery of ubiquitin-conjugation enzyme inhibitors from marine natural products.
University of Edinburgh School of Biological Sciences
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Prof M Auer, Dr N Carragher
Application Deadline: 13 December 2018
Ubiquitination is a key biochemical event which regulates most cell processes. Proteins are modified with ubiquitin, or ubiquitinated, through a series of reactions involving the E1, E2 and E3 enzymes.
Details
Type/Funding
  Ubiquitin chain recognition by deubiquitylating (DUB) enzyme complexes
University of Leeds Faculty of Biological Sciences
  Research Group: BBSRC White Rose DTP
  Dr E Zeqiraj, Dr D Tomlinson
Application Deadline: 7 January 2019
A studentship to study Ub signalling is available in the laboratories of Dr Elton Zeqiraj and Dr Darren Tomlinson at the University of Leeds.
Details
Type/Funding
  The ubiquitin proteasome system and neurodegenerative disease
University of Nottingham School of Life Sciences
  Dr L Bedford
Applications accepted all year round
The mechanisms that cause neurones to die in neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases remain unclear.
Details
Type/Funding
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