Continue with FacebookLooking to list your PhD opportunities? Log in here.
ubiquitin PhD Projects, Programmes & Scholarships
We have 21 ubiquitin PhD Projects, Programmes & Scholarships
PhD saved successfully
MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation
Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more
Ubiquitin and ubiquitin-like proteins in the DNA damage response and cancer
A self-funded PhD studentship is available in the laboratories of Christine Schmidt, Stefan Meyer and Anthony Whetton. Read more
Ubiquitin signals in Parkinson’s disease
Ubiquitin signalling controls almost every cellular process in humans, including targeting poorly folded proteins for destruction to prevent them harming the cell. Read more
Understanding the regulation of inflammation by the ubiquitin system.
Inflammatory responses rely on an intricate network of signalling events, which ensure that cells respond appropriately to insults, such as infections, toxic compounds, or cell damage. Read more
Ubiquitin-like modifications underlying Cell Differentiation and Biology in Trypanosomes
Post-translational protein modifications are major regulators of eukaryotic cell functions and include modifications by attachment of polypeptides such as ubiquitin and ubiquitin-like proteins (UBLs). Read more
Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation
Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more
Institute of Molecular, Cell and Systems Biology
Our institute houses a multi-disciplinary centre of excellence conducting fundamental and translational life science research underpinning health and food security. Read more
MSc by Research: Investigating mitochondrial autophagy mechanisms in Parkinson’s
Our lab has contributed to how two Parkinson’s disease-linked genes encoding the protein kinase, PINK1 and ubiquitin E3 ligase, Parkin, orchestrate a mitochondrial quality control pathway found in nearly every cell type including neurons. Read more
Last chance to apply
(EPSRC DTP) Mapping SUMO interactions in DNA repair using EPR, NMR and molecular modelling
Understanding the process by which DNA double-strand breaks are repaired via non-homologous end joining (NHEJ) is vital for the design and precision of future anti-cancer medicines and the optimisation of CRISPR/Cas9-based gene editing. Read more
MSc by Research: Signalling pathways controlling protein degradation upon stress
Increasing evidence shows that alterations and mutations in the UPS give rise to various human diseases, such as cancer and neurodegenerative disorders. Read more
MSc by Research: Regulation of the stability of the Notch intracellular domain in iPS derived presomitic mesoderm cells
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life. Read more
MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells
The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. . Read more
MSc by Research: Does CDK1 regulate NICD turnover in a cell cycle dependant manner in Drosophila Melanogaster?
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life, including cell fate specification within progenitors. . Read more
Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein
Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more
- 1
- 2