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We have 18 ubiquitin PhD Projects, Programmes & Scholarships

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ubiquitin PhD Projects, Programmes & Scholarships

We have 18 ubiquitin PhD Projects, Programmes & Scholarships

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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more
 Supervisor: Dr K Tanaka
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding gene regulation by HDAC1 complexes in development and cancer

University of Leicester Molecular and Cell Biology
Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
 Supervisor: Prof S Cowley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

University of Sheffield School of Biosciences
Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more
 Supervisor: Dr C Guo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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